Biomedical Materials

Developing advanced biomaterials and biomanufacturing technologies for the next generation of repair and regenerative therapies in orthopaedics


Dr Matteo D' Este

Focus Area Leader:
Biomedical Materials

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The Biomedical Materials focus area is committed to the design of advanced biomaterials and the development of manufacturing technologies to achieve improved patient care and outcome in musculoskeletal disorders.

We create biomaterials that react to environmental stimuli, that interact with cells and tissues and that are amenable to cutting-edge 3D printing and biofabrication technologies. We develop bio-processing technologies for cost-efficient tissue engineering approaches to regenerative, patient-tailored precision medicine. We design biomaterial surfaces and antibacterial delivery systems for prevention and treatment of infections.

By enhancing our knowledge of the biomaterials design, additive manufacturing and bioprocessing, we aim to advance patient care.

Selected collaborative projects

  • 2020-2023- Precision medicine for musculoskeletal regeneration, prosthetics and active ageing. (PREMUROSA Innovative Training Networks, partner, H2020 funded project, nber: 860462).
  • 2020-2024- Engineered full-organ 3D intervertebral disc as standardized model for studying disc degeneration and disease. (INDEED, coordinator SNF-ANR Bilateral project, nber: 310030E_189310).
  • 2020-2024- 3D Printed-Matrix Assisted Chemically Modified RNAs Bone Regenerative Therapy for Trauma and Osteoporotic Patients. (cmRNAbone, coordinator H2020 funded project, nber: 874790).
  • 2020-2026- Establishment of the Baltic Biomaterials Centre of Excellence. (partner, H2020 funded project, number 857287).


Selected scientific publications

Other focus areas

Progenitor Cell Biology and Mechanoregulation

Disc and Cartilage Biology

Sound Guided Tissue Regeneration

Bone Biology

Infection Biology

Meet the team

See more about the team on the Regenerative Orthopaedics research program