Field-Assisted Biofabrication

Sound patterns of Calcium phosphate particles in hydrogel

Tiziano Serra, Assoc Prof

Focus Area Leader:
Field-Assisted Biofabrication

Profile page

Field-Assisted Biofabrication (FAB) team, focuses on advancing the engineering of living systems using extrinsic fields-based biofabrication technologies, such as hydrodynamic waves, magnetic fields, light, and stimuli-responsive materials for modelling and regeneration. 

Our team leverages FAB approaches to spatially pattern and assemble cells, aggregates, organoids, and extracellular matrices in a controlled and programmed manner, with the goal of creating advanced human in vitro models, in alignment with the 3Rs philosophy. 

One of the key innovations developed by our team is Sound Induced Morphogenesis (SIM), a novel technology that enables contactless bioassembly, under fast and mild culture conditions, by hydrodynamic waves, opening new frontiers for functional and morphologically relevant tissue generation. In 2020, SIM technology was licensed to mimiX Biotherapeutics, a successful Swiss startup that is now advancing in clinical translation. SIM was selected as part of the “Technology Outlook 2023” by the Swiss Academy of Engineering Sciences, SATW. Implants from a loudspeaker: Technology Outlook  

Selected collaborative projects

  • PREMUROSA, H2020 MSCA – ITN 2019 "Precision medicine for musculoskeletal regeneration, prosthetics, and active ageing"
  • FLAMIN-GO, H2020-NMBP-TR-IND, "From pathobiology to synovia on chip: driving rheumatoid arthritis to the precision medicine goal"
  • E - RegenMed2.0, Eurostar, EU
  • STRATAGEM New diagnostic and therapeutic tools against multidrug resistant tumours. Cost Action1710

Selected scientific publications

A multifunctional nanocomposite hydrogel for endoscopic tracking and manipulation
A stimuli-responsive nanocomposite for 3D anisotropic cell-guidance and magnetic soft robotics

Other focus areas

Progenitor Cell Biology and Mechanoregulation

Disc and Cartilage Biology

Biomedical Materials

Bone Biology

Infection Biology

Meet the team

See more about the team on the Regenerative Orthopaedics research program