Clinical Evidence Current Studies

Find out more about the 45 studies we are currently running in 40 countries.

Current studies in 2021

Short title	Project title	Principal coordinating investigator	Project ending	Current phase
MRONJ registry	An international, multicenter, prospective registry to collect data of treatment patterns of patients with Medication-Related OsteoNecrosis of the Jaw (MRONJ) and their outcome	Risto Kontio (University of Helsinki) and Sven Otto (Ludwig-Maximilian University, Munich)	2024	Monitoring
BCFx registry	International, multicenter, prospective registry to collect data of treatment patterns in patients with bilateral condylar fracture (BCFx) of the mandible	Risto Kontio (University of Helsinki) and Edward Ellis 3rd (University of Texas Health Science Center at San Antonio)	2024	Monitoring
OFx	International, multicenter, prospective registry to collect data on orbital fractures (OFx), their treatment and outcome	Eppo B Wolvius	2026	Monitoring
MFx 60+	International, multicenter, prospective registry to collect data in patients > 60 years suffering from mandibular fractures	Risto Kontio	2025	Monitoring
TMJ replacements	International, multicenter, prospective registry to collect data of patients treated with alloplastic temporomandibular joint (TMJ) replacements	Andreas Thor	2028	Monitoring

Short title	Project title	Principal coordinating investigator	Project ending	Current phase
EPOSO	The epidemiology, process and outcomes of spine oncology	Charles Fisher	2022	Publication
SDIM	Spinal deformity intraoperative monitoring: understanding and managing intraoperative neuromonitoring changes during spinal deformity surgery	Stephen Lewis	2022	Monitoring
PEEDS	Prospective evaluation of elderly deformity surgery	Stephen Lewis	2022	Analysis
MTRON	Metastatic tumor research and outcomes network: a multicenter prospective registry for the management of metastatic spine tumors	Charles Fisher	2024	Monitoring
PTRON	Primary tumor research and outcomes network: A multicenter prospective registry for the management of primary tumors of the spine	Jeremy Reynolds	2024	Monitoring
DegenPRO	Spine registry to collect outcome measures related to the disease status of patients with dpine disorders	Tim Yoon	2024	Monitoring
Spine_TL-A3-A4	Thoracolumbar burst fractures (AOSpine A3, A4) in neurologically intact patients: an observational, multicenter cohort study comparing surgical versus non-surgical treatment	Marcel Dvorak	2022	Monitoring
SCI POEM	Prognostic factors and therapeutic effects of surgical treatment for traumatic spinal column iInjury with spinal cord injury	Allard Hosman	2022	Publication
INTWIN	Traumatic incomplete tetraplegia without instability: a prospective multicenter feasibility study of outcomes and prognosis	Jefferson R Wilson	2026	Planning

Short title	Project title	Principal coordinating investigator	Project ending	Current phase
PPFx Registry	Multicenter prospective registry for periprosthetic fractures after hip or knee arthroplasty	Karl Stoffel	2023	Monitoring
CPP Patient Outcome Project I	Clinical Priority Program (CPP) Patient Outcome Project I: Translation, Cultural Adaptation and Cognitive Debriefing of Extension Items of PROMIS Physical Function item bank V2.0 in German and Spanish	Marilyn Heng, Claudia Hartmann	2024	Planning
CPP Patient Outcome Project II	Clinical Priority Program (CPP Patient Outcome Project II: GO FIT FAST - Gait Observation for Fully Individualized Treatment and Aftercare following Surgery and Trauma	Tim Pohlemann, Benedikt Braun	2024	Monitoring
CPP Patient Outcome Project III	Clinical Priority Program (CPP) Patient Outcome Project III: Development of interpretation guidance for clinicians to better understand meaning of PROMIS scores	Prakash Jayakumar, Marilyn Heng, Stephen Gwilym	2024	Monitoring
CPP Patient Outcome Project IV	Clinical Priority Program (CPP) Patient Outcome Project IV: Linking of PROMIS Physical Function to Legacy Measures in an Orthopaedic Patient Population	Marilyn Heng (center 1), Tim Pohlemann, Benedikt Braun (Center 2), Prakash Jayakumar (Center 3)	2024	Monitoring
CPP Patient Outcome Project V	Clinical Priority Program (CPP) Patient Outcome Project V: Norm Data - Collection of international Age-based Norm Data for interpretation of scores obtained from the newly extended PROMIS® Physical Function item bank version 2.0	Matthias Rose	2024	Monitoring
CPP Patient Outcome Project VI	Clinical Priority Program (CPP) Patient Outcome Project VI: Standard setting to develop PROMIS score severity threshold categories	Marilyn Heng	2024	Monitoring
AOFFP	Fragility Fractures of the Pelvis: Observational Outcome Study	Pol Maria Rommens	2024	Monitoring
PedOrtho	A prospective multicenter observational registry of pediatric orthopedic trauma and health outcomes in skeletally immature children	Kishore Mulpuri	2026	Monitoring