Clinical Evidence Completed Studies

Browse our completed studies

Completed studies

  • AO Trauma

    Short title

    Project title

    		 Principal Coordinating Investigator

    Clin.Trial.gov
    NCT number

    FFOB Hum

    The influence of local bone status on complications after surgical treatment of proximal humerus fractures

    		 Franz Kralinger, MD

    NCT01143675
    NonRandHum Comparison of conservative versus operative treatment of humerus shaft fractures. Prospective Cohort Study   NCT00205972
    PH Cons Documentation of the results of conservative treatment of proximal humeral fractures
    		    

    FFOB Rad

    The Influence of Local Bone Status on Complications After Surgical Treatment of Distal Radius Fractures

    		 Daniel A Rikli, PD

    NCT01144208
    CEA Chile Cost effectiveness analysis of scaphoid fractures in Chile
    		    

    Scaphold

    Operative Versus Conservative Treatment of Scaphoid Fractures

    		 Markus Schaedel-Hoepfner, Prof. MD

    NCT00205985
    LAMOS Latin America Hip Fracture Mortality Study Wiliam Belangero, Dr. med NCT01650064

    SI Screw

    Accuracy of Navigation in Placement of Accuracy of Navigation in Placement of Sacroiliac Screw

    		Ulrich C. Stöckle, Prof. MD

    NCT00955565
    LFN Treatment of femoral fractures with the Expert™ Lateral Femoral Nail
    		    
    LISS-DF Minimal invasive Frakturstabilisierung von distalen Femurfrakturen mit dem LIS-System: Eine prospektive Multizenterstudie
    		    
    HTO Navi Prospective Study comparing the deviation from the leg-axis in navigated vs. non-navigated open-wedge high tibial osteotomies, receiving TomoFix®
    		   

    TEFTOM

    The role of patient expectations in traumatic orthopedic outcomes: the development of the trauma expectation factor trauma outcome measure

    		Michael Suk, Professor

    NCT01126398
    UTN Protect Randomized controlled trial to evaluate the operative stabilization of closed and open diaphyseal fractures of the tibia using gentamicin-coated titanium nails (UTN/Expert TN + antibiotic coating®)
    		    
    MOXFQ TMT Fusion Plate vs. Two Crossed Screws (TMT)
     
    		 Ian Winson, MB ChB, FRCS
    		 NCT02096146
    TEFTOM
    		 The role of patient expectations in traumatic orthopedic outcomes (TEFTOM Eurasia) TEFTOM: The trauma expectation factor trauma outcomes measure
    		 Reto Babst
    		 NCT01134354
    CPP Bone Infection Registry
    		 Implementation of a registry on bone infection to improve patient outcomes and research efforts
    		 Stephen Kates
    		 NCT01677000
    GFC
    		 A prospective multicenter cohort study to evaluate the benefit of the geriatric fracture center concept
    		 Michael Blauth
    		 NCT02297581
    MobiChina
    		 A prospective multicenter cohort study to evaluate the effect of early mobilization of patients after hip fracture fixation on functional outcomes in the Chinese population
    		 Frankie Leung
    		 NCT02296086
    MobiChina
    		 MobiChina survey
    		 Frankie Leung
    		 n/a
    CPP III pre-project
    		 Clinical Priority Program (CPP III pre-project prox humerus)
    		 Laurent Audigé
    		 n/a
  • AO Spine

    Short title

    Project title

    		 Principal Coordinating Investigator

    Clin.Trial.gov
    NCT number

    CSM-I

    An Assessment of Surgical Techniques for Treating Cervical Spondylotic Myelopathy. International Multicenter Study

    		 Michael Fehlings, MD, PhD

    NCT00565734

    CSM

    An Assessment of Surgical Techniques for Treating Cervical Spondylotic Myelopathy. Retrospective Study

    		 Michael Fehlings, MD, PhD

    NCT00285337

    GOF

    Comparing Surgical to Conservative Management in the Treatment of Type II Odontoid Fractures Among the Elderly

    		 Alexander R Vaccaro, MD

    NCT00266929

    ScoliRisk 1

    Neurologic Complications in Spinal Deformity Surgery

    		 Lawrence Lenke, MD

    NCT01305343

    PAM

    Posterior ligament complex assessment without magnetic resonance image in thoracolumbar fractures (T11-L2): A diagnostic test study to analyze sensitivity and specificity (PAM) .

    		Shanmuganathan Rajasekaran 

    NCT02950532

     

    Systematic literature research and review on biomaterials (allograft including DMB) used in cervical and lumbar fusion.

    Jim Youssef; Hans Jörg Meisel

    n/a

    Scoli-RISK-1

    Evaluation of neurologic complications associated with surgical correction of adult spinal deformity

    		 Lawrence Lenke

    NCT01305343

    Scoli-RISK-1-extension

    Evaluation of neurologic complications associated with surgical correction of adult spinal deformity: 5-year follow-up extension

    		 Lawrence Lenke

    NCT02949245

     

    C-Classification

    		 Alexander R Vaccaro, MD

    n/a
  • AO CMF

    Short title

    Project title

    		 Principal Coordinating Investigator

    Clin.Trial.gov
    NCT number

    Orbita1

    Evaluation of orbital volume differences

    		    

    Orbita 3

    Prospective Multicenter Trial to Compare Preformed vs Non Preformed Orbital Implants (Orbita 3)

    		 Niels Gellrich

    NCT01121159

    DMFx

    A Multicenter Randomized Controlled Clinical Investigation to Investigate the Treatment of Double (Bilateral) Mandibular Fractures

    		 Risto Kontio and Edward Ellis 3rd

    NCT02341443

    Orbita 3

    Orbita 3 - Additional publication

    		   n/a
  • AO Technical Commission

    Short title

    Project title

    		 Principal Coordinating Investigator

    Clin.Trial.gov
    NCT number

      Comparison of open surgery versus endoscopic approach in condylar neck fractures - functional outcome, cosmetic outcome, patient satisfaction (CMF Condylar Neck - nonrandomized)
    		 Prof Dr Rainer Schmelzeisen
    		 NCT00206011

    PHILOS+

    A Multicenter Randomized Controlled Trial to Investigate the Treatment Outcome of PHILOS Screw Augmentation Compared to PHILOS Without Augmentation in Older Adult Patients With Proximal Humerus Fractures

    		 Franz Kralinger

    NCT01847508

    LCP DR 2.4mm

    Surgical Plate Osteosynthesis of Distal Radius Fractures: Prospective study of the Locking Compression Plate (LCP DR 2.4mm)

    		    

    LCP DR 3.5mm

    Surgical Plate Osteosynthesis of Distal Radius Fractures: Prospective study of the Locking Compression Plate (LCP DR 3.5mm)

    		  

     

    LCP DR Cons

    Conservative treatment with or without reduction of distal radius fractures

    		    

    LCP DR Retro

    Distal radius fracture treatment. A retrospective study

    		  

    LCP-FU Series

    Evaluation of the safety of the LCP design on the outcome of fracture treatment

    		    

    VA LCP DR

    2.4 mm Variable Angle LCP Two-Column Volar Distal Radius

    		Jesse B Jupiter, MD
    Andreas Schierz, MD

    NCT01103297
    ACIS A Focused Registry on Anterior Cervical Interbody Spacer ACIS
    		 Robert Hes, MD
    		 NCT02016794

    FR TFNA

    A Focused Registry on the Titanium Trochanter Fixation Nail Advanced (TFNAdvanced™) - TFNA System in Patients With Proximal Inter-, Per- or Subtrochanteric Fractures

    		 Prof Michael Blauth

    NCT02305121

    ProFHER

    ProFHER Trial critical appraisal

    		Simon Lambert
    		 n/a

    FR QSP

    A prospective and retrospective, multicenter registry for surgeon-based evaluation of the "Quadrilateral Surface Plate" used for acetabular fractures 

    		 Tim Pohlemann

    NCT01839565
    INFINITI (Infection India)
    		 (Infection India) Infection rates following internal fixation of open and closed tibia fractures in india (INFINITI): a prospective multi-center observational study 
    		 Prakash J Doshi, MD
    		 NCT01691599
    CIOS
    		 Incidence of complications after instrumentatiom of the opsteoporotic spine: a systematic review
     
    		 Prof Frank Kandziora
    		 n/a
    FR SmartFix
    		 Data collection with a novel biofeedback technology for continuous monitoring of bone healing (FR SmartFix)
     
    		 Dankward Hoentzsch
    		 NCT02094209
    FR TFNA A focused registry on the Titanium Trochanter Fixation Nail Advanced (TFNAdvanced™)– TFNA system in patients with proximal inter-, per- or subtrochanteric fractures Michael Blauth NCT02305121
    PFNA Augmentation
    		 Comparison of Proximal Femoral Nail Antirotation (PFNA) versus PFNA Augmentation for the treatment of closed unstable trochanteric fractures – A randomized-controlled trial (PFNA Augmentation)
    		 Christian Kammerlander
    		 NCT01473082
    Pilon
    		 Quality of fracture reduction and its influence on functional results in patients with pilon fractures
    		 Christoph Sommer, MD
    		 NCT01316289
    SmartFix II - Moticon A prospective case series study to monitor healing progression and real life weight bearing after tibial fracture using smart biofeedback systems Stefan Döbele NCT03166267
    TFNA weight bearing A prospective study to investigate postoperative real life weight bearing measured in patients treated with a Trochanter Fixation Nail Advanced Michael Blauth, Karl Stoffel NCT03160508
  • AO Education Institute

    Short title

    Project title

    		 Principal Coordinating Investigator

    Clin.Trial.gov
    NCT number

    PI-Program

    Optimizing intraoperative imaging during proximal femur fracture fixation- a performance improvement program for surgeons

    		 Andreas Platz
    		 NCT02272972
  • AO Research Institute

    Short title

    Project title

    		 Principal Coordinating Investigator

    Clin.Trial.gov
    NCT number

    SmartFix I

    Clinical data collection with a novel biofeedback technology
    for continuous monitoring of bone healing

    		Dankward Höntzsch

    NCT02094209

    Moticon SmartFix II

    A prospective case series study to monitor healing progression
    and real life weight bearing after tibial fracture using smart
    biofeedback systems

    		 Stefan Döbele

    NCT03166267

Find out more

Clinical Evidence

AO ITC clinical research to global standards (ISO 14155 and ICH GCP), drawing on in-house medical and scientific expertise.

Find out more

Clinical Research Fellowship

Apply now to take part in a clinical research fellowship at the AO's Innovation Translation Center.

Find out more

Clinical Science

Clinical evidence generated through AO clinical studies can be accessed in the form of journal articles, presentations at scientific meetings, final study reports, guidelines, classifications, and/or news on the AO website.

Find out more