Total hip arthroplasty for treating childhood infection sequelae

Childhood hip infection may lead to a broad spectrum of residual deformities in the hip. Although total hip arthroplasty (THA) is the treatment of choice to eliminate pain and improve functions for end-stage osteoarthritis, THA in adult patients with childhood hip infection sequelae can be technically challenging because of the extensive and complex deformities. In addition, many surgeons hesitate to offer THA to patients with a history of childhood septic arthritis (SA) for fear of reactivating or recurrent infections. In this article, Youn-Soo Park from the Department of Orthopedic Surgery, Samsung Medical Center, Seoul, South Korea, updates us on the status of THA in patients with childhood infection sequelae in the hip joint—the surgical challenges, prognostic factors, and outcome.


Youn-Soo Park

AO Recon Education Forum
Department of Orthopedic Surgery
Samsung Medical Center
Seoul, South Korea


Childhood septic arthritis

Septic arthritis can occur in patients of all ages, but because of the anatomical and physiological characteristics of joints in children, it is mostly found in young children [1]. It is a rare but serious, potentially devastating disease. In a prospective study, it was estimated at an incidence of 1:20,000 among the pediatric population in a region in South Africa [2], and others have estimated it at 1–5 cases per 100,000 in children in developed countries [1]. Correct diagnosis and timely treatment are important for good outcomes but can still result in residual deformities. Childhood hip infection sequelae are more common in poorer, less developed countries [1–3].

The onset of symptoms of SA can be joint swelling and/or sudden joint pain, malaise, a mild limp, inability to bear weight, or the recognition that a leg was not actively moving in an infant; there may or may not be fever at presentation [1, 2, 4, 5]. Staphylococcus aureus (S aureus) is the most frequently encountered pathogen, other organisms such as Streptococcus pneumoniae and Kingella kingae are also frequently found. The frequency of the pathogen can differ depending on the child's age and geographic location [1, 2, 4–6].

Read the full article with your AO login


  • What to do with the long turnaround time of a microbiological culture test?
  • Adult patients with hip infection sequelae
  • Is there a good classification system for infection sequelae of the hip?
  • Challenges of total hip arthroplasty in treating infection sequelae
  • THA in infection sequelae: Which approach is better?
  • What is a suitable quiescent period to avoid reactivation of a previous infection?
  • Childhood infection sequelae vs developmental dysplasia of the hip: a matched-pair study
  • Prognostic factors influencing outcomes of total hip arthroplasty in infection sequelae
  • Conclusion

Part 1 | Dysplastic high-riding hips

Part 3 | Patients with skeletal dysplasia

Additional AO resources

Access videos, tools, and other assets.

Contributing experts

This series of articles was created with the support of the following specialists (in alphabetical order):

Seung Beom Han

Department of Orthopedics
Korea University Medical Center
Seoul, South Korea

Seung-Jae Lim

Department of Orthopedic Surgery
Samsung Medical Center
Seoul, South Korea

Youn-Soo Park

AO Recon Education Forum
Department of Orthopedic Surgery
Samsung Medical Center
Seoul, South Korea

This issue was written by Maio Chen, AO Innovation Translation Center, Clinical Science, Switzerland.

References

  1. Erkilinc M, Gilmore A, Weber M, et al. Current Concepts in Pediatric Septic Arthritis. J Am Acad Orthop Surg. 2021 Mar 1;29(5):196–206.
  2. Nunn TR, Cheung WY, Rollinson PD. A prospective study of pyogenic sepsis of the hip in childhood. J Bone Joint Surg Br. 2007 Jan;89(1):100–106.
  3. Park YS, Moon YW, Lim SJ, et al. Prognostic factors influencing the functional outcome of total hip arthroplasty for hip infection sequelae. J Arthroplasty. 2005 Aug;20(5):608–613.
  4. Jeyanthi JC, Yi KM, Allen JC, Jr., et al. Epidemiology and outcome of septic arthritis in childhood: a 16-year experience and review of literature. Singapore Med J. 2022 May;63(5):256–262.
  5. Wang CL, Wang SM, Yang YJ, et al. Septic arthritis in children: relationship of causative pathogens, complications, and outcome. J Microbiol Immunol Infect. 2003 Mar;36(1):41–46.
  6. Ilharreborde B. Sequelae of pediatric osteoarticular infection. Orthop Traumatol Surg Res. 2015 Feb;101(1 Suppl):S129–137.
  7. Lim SJ, Park YS. Modular cementless total hip arthroplasty for hip infection sequelae. Orthopedics. 2005 Sep;28(9 Suppl):s1063–1068.
  8. D'Apolito R, Bandettini G, Rossi G, et al. Low Reinfection Rates But a High Rate of Complications in THA for Infection Sequelae in Childhood: A Systematic Review. Clin Orthop Relat Res. 2021 May 1;479(5):1094–1108.
  9. Malhotra R, Batra S, Sugumar PA, et al. Clinical outcome in total hip arthroplasty for septic sequelae in childhood : a retrospective study. Bone Jt Open. 2022 Apr;3(4):314–320.
  10. Luo Y, Yang Z, Yeersheng R, et al. Clinical outcomes and quality of life after total hip arthroplasty in adult patients with a history of infection of the hip in childhood: a mid-term follow-up study. J Orthop Surg Res. 2019 Feb 1;14(1):38.
  11. Park C-W, Lim S-J, Park Y-S. Modular Stems: Advantages and Current Role in Primary Total Hip Arthroplasty. Hip Pelvis. 2018 9/;30(3):147–155.
  12. Choi IH, Pizzutillo PD, Bowen JR, et al. Sequelae and reconstruction after septic arthritis of the hip in infants. J Bone Joint Surg Am. 1990 Sep;72(8):1150–1165.
  13. Park CW, Lim SJ, Cha YT, et al. Total Hip Arthroplasty With Subtrochanteric Shortening Osteotomy in Patients With High Hip Dislocation Secondary to Childhood Septic Arthritis: A Matched Comparative Study With Crowe IV Developmental Dysplasia. J Arthroplasty. 2020 Jan;35(1):204–211.
  14. Zhang L, Chu Y, Shao H, et al. Cementless Total Hip Arthroplasty for Adult Patients With Sequelae From Childhood Hip Infection: A Medium-Term Follow-Up Study. J Arthroplasty. 2020 Jul;35(7):1885–1890.
  15. Deirmengian CA. CORR Insights®: Low Reinfection Rates but a High Rate of Complications in THA for Infection Sequelae in Childhood: A Systematic Review. Clin Orthop Relat Res. 2021 May 1;479(5):1109–1111.
  16. Kim YH. Total arthroplasty of the hip after childhood sepsis. J Bone Joint Surg Br. 1991 Sep;73(5):783–786.
  17. Kim YH, Oh SH, Kim JS. Total hip arthroplasty in adult patients who had childhood infection of the hip. J Bone Joint Surg Am. 2003 Feb;85(2):198–204.
  18. Yang Y, Yu QP, Wang SL, et al. Outcomes after Total Hip Arthroplasty Using a Cementless S-ROM Modular Stem for Patients with High Hip Dislocation Secondary to Hip Pyogenic Arthritis. Orthop Surg. 2019 Jun;11(3):460–466.