AO Spine Knowledge Forum Trauma
AO Spine KF Trauma addresses the growing health care issue of spinal trauma with a goal to:
- improve the care of all patients with (suspected) spinal column injury;
- advance knowledge about patterns of spinal injury and their consequences;
- develop reliable classification systems based on the systematic study of all available knowledge;
- develop simple, clinically useful, diagnostic and therapeutic algorithms.
Ongoing research projects
AO Spine Infection Classification System
Alexander R. Vaccaro
To develop and validate a simple and comprehensive scheme for the classification of primary spinal infections
Phase 1: Develop a classification system for primary spinal infections incorporating clinical factors relevant for surgical decision-making.
Phase 2: Internal Validation - assess the classification's reliability and accuracy and identify areas of disagreement which required further refinement.
Phase 3: International Validation - assess the classification's reliability and accuracy globally
Phase 4: Develop a global treatment algorithm
‘All for All’ radiology protocol in spine trauma - STIR
Pushpa Bhari Thippeswamy Rishi Kanna
To investigate the efficacy of a single Short Tau Inversion Recovery (STIR) MRI sequence in providing sufficient information for the spine surgeon to a) classify the fracture, b) assess the presence of instability, and c) decide on the nature of treatment in patients with a thoracolumbar fracture and without neurological deficit.
Erector Spinae Plane Block and Analgesia
Does erector spinae plane block decrease the amount of analgesia needed after mini-invasive posterior transpedicular stabilization in patients with vertebral body fracture. Are there any peri or postoperative complications?
Aims to evaluate if the use of an erector spinae plane block (ESP) leads to reduction of analgesic demands in the perioperative period in patients undergoing Mini-invasive spinal surgery after fracture of the vertebral body in thoracic or lumbar spine.
AO Spine-DGOU Osteoporotic Fracture Classification System
To develop an easy and reliable classification system to support therapeutic decision making in Osteoporotic Vertebral-Fractures
AO Spine Post-traumatic Deformity (PTDEF)
AO Spine post-traumatic deformity and its relation to health-related quality of life outcomes in spine trauma (AOSpine PTDEF)
Lorin M. Benneker
- Aims to establish a definition for post-traumatic deformity through systematic review of the literature.
- Aims to find consensus among experts on factors clinically significant to post-traumatic deformity.
- Aims to understand the relationship between post-traumatic deformity and the long-term health-related quality of life outcomes measured with the ODI in patients who have undergone a traumatic injury of their spine.
* Thoracolumbar Burst Fractures (AOSpine TLA3-A4) in Neurologically Intact Patients
An observational, multicenter cohort study comparing surgical versus non-surgical treatment
Aims to establish and quantify the difference in the patients’ clinical outcomes after surgical treatment as compared to non-surgical treatment of thoracolumbar burst fractures within the first year after treatment with the Oswestry Disability Index (ODI)
ClinicalTrials.gov Identifier: NCT02827214
* This AO Spine-sponsored study is executed with support from the AO Innovation Translation Center (AO ITC).
** Award-winning project
Completed research projects
AO Spine Trauma Focus Issue 2017
The Spine Trauma Focus Issue aimed to synthesize the latest available knowledge regarding spine trauma and spinal cord injury controversies, AO Spine outcome instruments, AO Spine Classification systems and presentation of cases.
Effect of Riluzole on Osteogenic Differentiation
Effect of riluzole on osteogenetic differentiation of human mesenchymal stem cells and human osteoblasts
Aimed to understand the effects of Riluzole on mesenchymal stem cells' ability to convert to osteoblasts, on osteogenic differentiation, and possible toxicity of the drug on these cells
Value of CT and MRI
The additional value of computed tomography (CT) and magnetic resonance imaging (MRI) in determining the fracture severity and management in spinal column injuries
Aimed to define and determine the value of a CT scan and an MRI in addition to plain radiographs in a cohort of spinal fractures of various severities
KF Trauma Steering Committee
St. Marien, Erlangen, Germany
University Medical Centers
Utrecht, the Netherlands
Alexander R. Vaccaro
Thomas Jefferson University
Vancouver General Hospital
University of Bern
Cajuru Hospital, Catholic University of Paraná
Gregory D. Schroeder
Rothman Orthopaedic Institute,
Thomas Jefferson University
Assiut University Medical School
Harborview Medical Center
University of Washington
KF Trauma Advisory Board
Swedish Neuroscience Institute
KF Trauma Associate Members
Sebastian Bigdon, Inselspital - University Hospital Bern, Bern, Switzerland
Joseph Butler, Mater Misericordiae University Hospital, Dublin, Ireland
Jose A. Canseco, The Rothman Orthopaedic Institute, Thomas Jefferson University, Philadelphia, USA
Gaurav Dhakal, National Trauma Center, National Academy of Medical Sciences, Kathmandu, Nepal
Andrei Fernandes Joaquim, University of Campinas, Campinas, Brazil
Martin Holas, Teaching Hospital F. D. Roosevelt, Banská Bystrica, Slovakia
Rishi Kanna, Ganga Hospital, Coimbatore, India
Sander Muijs, University Medical Center Utrecht, Utrecht, the Netherlands
Marko Neva, Tampere University Hospital, Tampere, Finland
Eugen Cezar Popescu, “Prof. Dr. N. Oblu” Emergency Hospital, Iasi, Romania
Philipp Schleicher, BG Unfallklinik am Main, Frankfurt, Germany
Ulrich Spiegl, Universitätsklinikum Leipzig, Leipzig, Germany
Masahiko Takahata, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Hokkaido, Japan
Jin W. Tee, The Alfred Hospital, Melbourne, VA, Australia
Pushpa Bhari Thippeswamy, Ganga Hospital, Coimbatore, India
Gaston Camino Willhuber, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
Ratko Yurac, Clínica Alemana de Santiago, Santiago, Chile
“Facing new challenges in spinal trauma deserves up to date recommendations for diagnostics and treatment. We are closing the gap between beliefs and evidence.”
Klaus Schnake, Chairperson KF Trauma