AO Research Institute Davos publications and activity reports
eCM Journal
Published by AO Research Institute Davos (ARI), Impact Factor 4.325.
eCM is the number one world-wide in trauma research journal and is the official research journal of AO CMF, AO Trauma, Biometal, European Orthopedic Research Society (EORS), Scandinavian Society for Biomaterials (ScSB), Swiss Society for Biomaterials & Regenerative Medicine (SSB+RM), and Tissue & Cell Engineering Society (TCES).
AO Research Institute Davos activity reports
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2021
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2020
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2019
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2018
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2017
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2016
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2015
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2014
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2013
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2012
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2011
AO Research Institute Davos publications and dissertations
2022
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Abstracts published in journals
Anatomical analysis of different helical plate designs for distal femoral fracture fixation.
Br J Surg. 2022;109(Suppl 3):iii15-6 (Swiss Congress of Surgery / oral)Pastor T, Beeres FJP, Kastner P, Gehweiler D, Migliorini F, Nebelung S, Scaglioni MF, Souleiman F, Link B-C, Babst R, Gueorguiev B, Knobe M.
Anatomical analysis of different helical plate designs for proximal humeral shaft fracture fixation.
Br J Surg. 2022;109(Suppl 3):iii31 (Swiss Congress of Surgery / oral)Pastor T, Kastner P, Souleiman F, Gehweiler D, Migliorini F, Link B-C, Beeres FJP, Babst R, Nebelung S, Ganse B, Schoeneberg C, Gueorguiev B, Knobe M.
Low-profile dual mini-fragment plating of diaphyseal clavicle fractures. A biomechanical comparative analysis.
Br J Surg. 2022;109(Suppl 3):iii30-1 (Swiss Congress of Surgery / oral)Pastor T, Knobe M, van de Wall BJM, Rompen IF, Zderic I, Visscher L, Link B-C, Babst R, Gueorguiev B, Beeres FJP.
Biomechanical properties of a novel AC and CC stabilization tech-nique using a novel cadaveric system with integration of the deltoideotrapezoideal fascia.
Swiss Med Wkly. 2022;152(Suppl 259):10 S (swiss orthopaedics / oral)Bless N, Sailer J, Dalcanale F, De Wild M, Gueorguiev B, Zderic I, Knecht M, Müller A.
A reliable predictor of secondary lateral wall fracture following tro-chanteric fractures – an update.
Swiss Med Wkly. 2022;152(Suppl 259):33 S (swiss orthopaedics / oral)van Knegsel KP, Hsu C-E, Huang K-C, Benca E, Ganse B, Pastor T, Gueorguiev B, Varga P, Knobe M.
Anatomical analysis of different helical plate designs for distal femoral fracture fixation.
Swiss Med Wkly. 2022;152(Suppl 259):54 S (swiss orthopaedics / poster)Pastor T, Kastner P, Beeres F, Link B-C, Babst R, Gueorguiev B, Knobe M.
Anatomical analysis of different helical plate designs for proximal humeral shaft fracture fixation.
Swiss Med Wkly. 2022;152(Suppl 259):45 S (swiss orthopaedics / poster)Pastor T, Kastner P, Link B-C, Beeres F, Babst R, Gueorguiev B, Knobe M.
Training of rodent surgeons – current practice and available guidelines.
Lab Anim. 2022;56(1 Suppl):105 (FELASA / oral)Gantenbein F, Hartnack S, Buchholz T, Wever K, Ritskes-Hoitinga M, Zeiter S, Seebeck P.
Poster for guidance on aseptic technique during rodent surgery.
Lab Anim. 2022;56(1 Suppl):158 (FELASA / poster)Gantenbein F, Buchholz T, Zeiter S, Seebeck P.
Survey on current training practices of rodent surgeons.
Lab Anim. 2022;56(1 Suppl):159 (FELASA / poster)Gantenbein F, Hartnack S, Zeiter S, Seebeck P.
Systematic review on guidelines for good surgical practice in experimental rodent surgery.
Lab Anim. 2022;56(1 Suppl):158 (FELASA / poster)Gantenbein F, Buchholz T, Wever KE, Ritskes-Hoitinga M, Zeiter S, Seebeck P.
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Books and book chapters
Maxillary sinusitis.
In: Orsini JA, Grenager NS, De Lahunta A (eds). Comparative Veterinary Anatomy: A Clinical Approach.
Elsevier / Academic Press; 2022:1002-12Constant C. Cranial Cruciate Ligament Tear.
In: Orsini JA, Grenager NS, De Lahunta A (eds). Comparative Veterinary Anatomy: A Clinical Approach.
Elsevier / Academic Press; 2022:1205-1210Marchionatti E, Constant C. -
Conference presentations
Schol J, Warita T, Sako K, Grad S, Alini M, Sakai D, Watanabe M.
Effect of therapeutic IL1Ra and IL10 mRNA vehiculated by polymeric nanoparticles in osteochondral ex-vivo model: a new approach for osteoarthritis treatment.
ORS 2022 (poster)Basoli V, Traweger A, Plank C, Rip J, Alini M, Grad S. Comparison and optimization of sheep in vivo intervertebral disc injury model.
ORS 2022 (poster)Constant C, Hom W, Nehrbass D, Carmel E-N, Albers C, Deml MC, Gehweiler D, Lee Y, Hecht A, Grad S, Iatridis JC, Zeiter S. Strain induces hypertrophic differentiation of naïve human MSCs in a 3D in vitro model.
ORS 2022 (poster)Jörimann T, Füllemann P, Matthys R, Stoddart M, Verrier S. Porcine notochordal cell injected into a bovine organ culture model of intervertebral disc degeneration.
ORS 2022 (poster)Vernengo A, Bumman H, Kluser N, Jansen JA, Neidlinger-Wilke C, Wilke H-J, Alini M, Li Z, Grad S. MSC secretome as potential immunomodulatory and regenerative treatment strategy for IVD degeneration.
ORS 2022 (poster)Wangler S, Nüesch A, Chen Z, Häckel S, Albers CE, Bigdon S, Li Z, Alini M, Grad S. Cell micro-pellets: An alternative to single cell embedding in biomaterials to evaluate the effect of material properties on chondrogenic differentiation.
2022 OARSI (hybrid / poster)Schwab A, Staubli F, Stoddart MJ, D'Este M. Bioinks with controlled fiber architecture modulating cell behavior.
2022 ICRS (oral)Schwab A, Staubli F, Alini M, D'Este M. Cell therapy for cartilage repair-modelling – Increasing complexity of cartilage models.
2022 ICRS (oral)Stoddart M. Programming vasculature morphogenesis by using sound.
2022 ISBF Twitter poster conferenceDi Marzio N, Alini M, Serra T. From tuneable peptide self-assembly to biologically instructive materials.
2022 MRS spring meeting (oral)Wychowaniec JK, D'Este M, Elsawy M, Saiani A, Miller A, Crean J, Brougham DF. Intensively loaded intervertebral disc enhances the spontaneous calcium oscillation in CGRP-negative dorsal root ganglion neurons.
2022 ISSLS (oral)Grad S, Gewiess J, Eglauf J, Soubrier A, Alini M, Peroglio M, Ma J. Vertebral mesenchymal stromal cell transplantation for intervertebral disc repair; a preliminary rat tail disc degeneration study.
2022 ISSLS (oral)Sakai D, Schol J, Warita T, Sako K, Grad S, Alini M, Watanabe M. Shorter resting period between cycles induces stronger MSC response to mechanical stimuli.
2022 SVGO / SBMS (oral)Enzmann S, Matthys R, Stoddart M, Verrier S. Effect of strain on naïve human MSC differentiation, an in vitro bioreactor study.
2022 SVGO / SBMS (oral)Jörimann T, Füllemann P, Matthys R, Stoddart M, Verrier S. Advanced CT visualization improves the accuracy of orthopaedic trauma surgeons and residents in classifying proximal humeral fractures: a feasibility study.
2022 Orthopaedica Belgica (poster)Dauwe J, Mys K, Putzeys G, Schader JF, Richards RG, Gueorguiev B, Varga P, Nijs S. A porous media flow model for simulating flow of non-Newtoninan bone cement inside a deformable vertebra in the context of vertebroplasty.
2022 InterPore (oral)Trivedi Z, Gehweiler D, Wagner A, Gueorguiev B, Ricken T, Röhrle O. An in vitro large animal model to investigate the effect of celecoxib on discogenic pain-associated sensory neuronal sensitization.
2022 Global Spine Congress (oral)Häckel S, Ma J, Häne S, Eglauf J, Soubrier A, Peroglio M, Li Z, Hoppe S, Benneker L, Wangler S, Alini M, Grad S. Is cement augmentation of the sacroiliac screw biomechanically superior for fixation of B2 fractures of the sacrum?
2022 Global Spine Congress (oral)Lodde MF, Katthagen JC, Schopper C, Zderic I, Richards RG, Gueorguiev B, Raschke MJ, Hartensuer R. Validation of a novel device for digitally enhanced hands-on surgical training of intramedullary nail distal interlocking.
2022 Swiss Congress of Surgery (poster)Pastor T, Knobe M, Kastner P, Souleiman F, Pastor T, Gueorguiev B, Windolf M, Buschbaum J. Sound-based cell assembly to recreate complex tissue architectures for regenerative medicine.
2022 SSB+RM (oral)Guex AG, Krattiger LA, Carrara BM, Alini M, Ehrbar M, Serra T. Delivery of mesenchymal stromal cells using collagen membranes embedded in LEGO®-inspired multicomponent scaffolds for personalised mandibular defect repair.
2022 SSB+RM (oral)Hatt LP, Wirth S, Armiento AR, Ristaniemi A, Thompson K, Gehweiler D, Eglin D, Stoddart MJ. The influence of stiffness and protein coating on the neutrophil activation.
2022 SSB+RM (poster)Bektas EI, Wychowaniec JK, Miklosic G, Wesdorp MA, D'Este M. Differentially expressed microRNAs during early endochondral differentiation of human mesenchymal stromal cells as biomarkers for non-union fractures.
2022 SSB+RM (poster)Breulmann FL, Ramasamy S, Herzog M, Pandian GN, Della Bella E, Stoddart MJ. A multi-well bioreactor for cartilage tissue engineering.
2022 SSB+RM (poster)Ladner YD, Armiento AR, Stoddart MJ. Hyaluronan-collagen composite bioink for the printing of nucleus pulposus-like structures.
2022 SSB+RM (poster)Miklosic G, De Oliveira S, Grastilleur S, Hélary C, Ferguson SJ, D'Este M. Bone resembling composite biomaterial-ink consisting of hyaluronan, collagen and calcium phosphate particles for bone regeneration.
2022 SSB+RM (poster)van der Heide D, Della Bella E, Yuan H, de Groot-Barrère F, Stoddart MJ, D'Este M. Tyramine position dictates properties of 3D printable supramolecular self-assembling β-sheet peptide and tyramine-modified hyaluronan hydrogels.
2022 SSB+RM (poster)Wychowaniec JK, Edwards-Gayle CJC, Bektas EI, Eglin D, D'Este M. Extracellular matrix polymer-based cryogels mimicking the arcade-like structure of articular cartilage fabricated by directional freezing.
2022 SSB+RM (poster)Yamamoto T, Randriantsilefisoa R, Sprecher CM, D'Este M. Optimized collagen/hyaluronan formulations to develop a novel biomimetic ink to synthesize composite hydrogels for tissue engineering.
2022 PNG (poster)De Oliveira S, Miklosic G, D'Este M, Hélary C. Sound assembly of dorsal root ganglion multicellular system.
2022 ScSB (oral)Marani E, Ma J, Alini M, Serra T. Biocompatible Gallium doped hydroxyapatite.
2022 ScSB (oral)Mosina M, Siverino C, Stipniece L, Moriarty F, Locs J. Statistical analysis of complex proximal humeral fractures.
2022 QMSKI & ISUCBGehweiler D, Mys K, van Knegsel K, Pastor T, Visscher L, Dauwe J, Bashardoust A, Knill A, Gueorguiev B, Windolf M, Nijs S, Lambert S, Varga P. Automated Cobb angle measurement in adolescent idiopathic scoliosis: Validation of a previously-published deep learning method.
2022 IEEE ICHI (poster)Yan S, Constant C, Ramazanian T, Kremers HM, Larson N. Microextrusion-based anisotropic cell patterning within temperature-sensitive hydrogel matrices for annulus fibrosus regeneration.
2022 eCM (oral)Egger S, Alig G, D'Este M, Wychowaniec JK, Weiser JR, Grad S, Vernengo AJ. How to create artificial disc degeneration by enzyme digestion for biomechanical testing of biomaterials.
2022 eCM (oral)Jansen JU, Teixeira GQ, Vernengo A, Grad S, Benz K, Neidlinger-Wilke C, Wilke H-J. Anti-inflammatory and pro-anabolic effects of 5-aminosalicylic acid on inflammatory human osteoarthritic chondrocytes in vitro.
2022 eCM (oral)Li KH, Zhu Y, Zhang P, Alini M, Grad S, Li Z. Extracellular Vesicles (MSC-EV) - influence on cartilage regeneration in osteoarthritic surroundings.
2022 eCM (oral)Ossendorff R, Börger V, Wirtz DC, Grad S, Giebel B, Schildberg FA. A novel viscoelastic bovine intervertebral disc finite element model.
2022 eCM (oral)Ristaniemi A, Šećerović A, Grad S, Ferguson SJ. Development of electrochemical nitric oxide microsensors for the real time monitoring of inflammation in chondrocytes.
2022 eCM (poster)Antonacci P, Belcastro L, Rocchitta G, Arduini F, Serra PA, Alini M, Grad S, Basoli V. Effect of therapeutic IL1Ra and IL10 mRNA vehiculated by polymeric nanoparticles in osteochondral ex-vivo model: a new approach for osteoarthritis treatment.
2022 eCM (poster)Basoli V, Traweger A, Plank C, Rip J, Alini M, Grad S. Notochordal cells encapsulated within hydrogel in an enzymatic bovine IVD degeneration model.
2022 eCM (poster)Bumann H, Kluser N, Soubrier A, Secerovic A, Zuncheddu D, Williams R, Snuggs J, Janani R, Sammon C, Jansen JU, Neidlinger-Wilke C, Wilke H-J, Le Maitre c, Vernengo A, Grad S. Cortical microarchitecture impacts distal clavicle fracture morphology.
2022 eCM (poster)Gewieß J, Sprecher CM, Milz S, Gleich J, Helfen T. Influence of mechanical loading regimes on spontaneous response of dorsal root ganglion neurons.
2022 eCM (poster)Gewiess J, Eglauf J, Soubrier A, Grad S, Alini M, Peroglio M, Ma J. In vitro evaluation of ovine IVD cells interactions with a collagen/hyaluronic acid biomaterial ink: On the way to a bio-printed IVD model.
2022 eCM (poster)Grastilleur S, Humbert P, Miklosic G, de Oliveira S, Halgand B, Loll F, Delplace V, D'Este M, Hélary C, Clouet J, Fusellier M, Guicheux J, Le Visage C. Hyaluronan-collagen composite bioink for the printing of nucleus pulposus-like structures.
2022 eCM (poster)Miklosic G, De Oliveira S, Grastilleur S, Hélary C, Ferguson SJ, D'Este M. A new generation of multiaxial spine bioreactor for advanced studies of intervertebral disc degeneration and repair.
2022 eCM (poster)Secerovic A, Ristaniemi A, Li Z, Crivelli F, Heub S, Ledroit D, Alini M, Weder G, Ferguson S, Grad S. Development of a bone remodelling in vitro model.
2022 e CM (poster)Sieberath A, Eglin D, Della Bella E, Sprecher C, Ferreira AM, Gentile P, Dalgarno K. Influence of traction on intervertebral disc mechanobiology: preliminary results in a bovine organ culture.
2022 eCM (poster)Soubrier A, Kasper H, Alini M, Jonkers I, Grad S. Enzyme-induced bovine explant models of intervertebral disc degeneration.
2022 eCM (poster)Vernengo A, Bumann H, Kluser N, Soubrier A, Gewiess J, Jansen JU, Neidlinger-Wilke C, Wilke H-J, Grad S. The role of Noggin in TGF-β1 or TGF-β3 driven chondrogenesis of BMMSCs.
2022 eCM (poster)Wen L, Armiento A, Creemers L, Stoddart MJ. Effects of different glucose supplementation on bovine intervertebral disc organ cultures under physiological loading.
2022 eCM (poster)Zuncheddu D, Kluser N, Bumann H, Creemers LB, Grad S. Anatomical analysis of different helical plate designs for distal femoral fracture fixation.
2022 EFORT (oral)Gueorguiev B, Pastor T, Beeres FJP, Kastner P, Gehweiler D, Migliorini F, Nebelung S, Scaglioni MF, Souleiman F, Link B-C, Babst R, Knobe M. Anatomical analysis of different helical plate designs for proximal third humeral shaft fracture fixation.
2022 EFORT (oral)Gueorguiev B, Pastor T, Kastner P, Souleiman F, Gehweiler D, Link B-C, Peeres FJP, Babst R, Nebelung S, Ganse B, Richards G, Knobe M. Is anterior variable angle locked plating of simple and complex patella fractures advantageous over tension band wiring? A biomechanical cadaveric study.
2022 EFORT (oral)Gueorguiev B, Stoffel K, Zderic I, Sanchez E, Woodburn W, Castle R, Penman J, Sommer C. Low-profile dual mini-fragment plating of diaphyseal clavicle fractures. A biomechanical comparative analysis.
2022 EFORT (oral)Zderic I, Pastor T, Beeres F, van de Wall B, Rompen I, Visscher L, Link B-C, Babst R, Gueorguiev B, Knobe M. In vitro methodology for systematic CT investigation of the periclavicular space. 2022 EFORT (poster)
Gehweiler D, Pastor T, Gueorguiev B, Jaeger M, Lambert S. Effect of weightbearing and foot position on 3D distal tibiofibular joint parameters. 2022 EFORT (poster)
Gueorguiev B, Souleiman F, Heilemann M, Hennings R, Hepp P, Richards G, Osterhoff G, Gehweiler D. Biomechanical analysis of helical versus straight plating of proximal third humeral shaft fractures.
2022 EFORT (poster)Zderic I, Pastor T, van Knegsel K, Richards G, Gueorguiev B, Knobe M. Helical plating of proximal third humeral shaft fractures. A biomechanical comparative study.
2022 EFORT (poster)Zderic I, Pastor T, van Knegsel K, Richards G, Gueorguiev B, Knobe M. Influence of cartilage loss on shoulder instability - a biomechanical study.
2022 EFORT (poster)Zderic I, Souleiman F, Pastor T, Varga P, Helfen T, Richards G, Gueorguiev B, Theopold J, Osterhoff G, Hepp P. Osteoarthritic knees can be quantified with in vivo scanners.
2022 ESB (Biomechanics / oral)Antonacci P, Dauwe J, Varga P, Ciric D, Gehweiler D, Gueorguiev B, Mys K. Effect of instrumentation inaccuracies on biomechancial and computational failure risk of fracture fixations.
2022 ESB (Biomechanics / oral)Mischler D, Tenisch L, Schader JF, Dauwe J, Gueorguiev B, Windolf M, Varga P. Systematic validation of finite element simulations of locking plate fixations.
2022 ESB (Biomechanics / oral)Mischler D, Knecht M, Varga P. Advances in fixation strength of reorienting rectangular triple pelvic innominate osteotomy.
2022 ESB (Biomechanics / oral)Richter J, Ciric D, Kalchschmidt K, D'Aurelio C, Pommer A, Dauwe J, Gueorguiev B. Light-curable fixation comparable with plates in torsion.
2022 ESB (Biomechanics / oral)Schwarzenberg P, Colding-Rasmussen T, Hutchison DJ, Mischler D, Horstmann P, Petersen MM, Malkoch M, Wong C, Varga P. Validated finite element simulation of porous titanium samples under fatigue loading for design optimization.
2022 ESB (Biomechanics / oral)Vautrin A, Aw J, Attenborough E, Varga P. Biomechanical analysis of helical versus straight plating of proximal third humeral shaft fractures.
2022 ESB (Biomechanics / oral)Zderic I, Pastor T, van Knegsel K, Link BC, Beeres FJP, Migliorini F, Babst R, Nebelung S, Ganse B, Schoeneberg C, Gueorguiev B, Knobe M. On measuring implant fixation stability in ACL reconstruction.
2022 ESB (Biomechanics / poster)Benca E, Zderic I, Caspar J, van Knegsel K, Hirtler L, Gueorguiev B, Windhager R, Widhalm H, Varga P. In vitro testing of bone biomaterials - opportunities and challenges.
2022 TERMIS EU (oral / invited Keynote)Stoddart MJ. Differentially expressed microRNAs during endochondral differentiation of human bone marrow derived mesenchymal stromal cells to identify possible biomarkers for non-union fractures.
2022 TERMIS EU (oral)Breulmann F, Herzog M, Stoddart M, Della Bella E. Improving chondrogenic potential of mesenchymal stromal cells by siRNA delivery in hydrogels.
2022 TERMIS EU (oral)Chen G, Basoli V, Guex AG, Stoddart M, Della Bella E. Controlling the shape of microcapillary networks in 3D in vitro models through sound patterning.
2022 TERMIS EU (oral)Di Marzio N, Guex AG, Alini M, Serra T. Cell density matters: Local cell density enhancement by sound to increase the therapeutic efficacy in regenerative medicine
2022 TERMIS EU (oral)Guex AG, Krattiger LA, Carrara BM, Alini M, Ehrbar M, Serra T. Delivery of mesenchymal stromal cells using collagen membranes embedded in LEGO®‐inspired multicompontent scaffolds for personalised mandibular defect repair.
2022 TERMIS EU (oral)Hatt LP, Wirth S, Armiento AR, Ristaniemi A, Thompson K, Gehweiler D, Eglin D, Stoddart MJ. Development of bioprinted osteochondral tissue: an in-vitro model for drug discovery.
2022 TERMIS EU (oral)Jahangir S, Vecstaudza J, Canciani E, Locs J, Alini M, Serra T. Engineering dorsal root ganglion multicellular system towards in vivo cross excitation function.
2022 TERMIS EU (oral)Ma J, Marani E, Alini M, Serra T. Towards the development of multiaxial loading bioreactor for intervertebral disc studies: validation of an ex vivo organ model and customized sample holder.
2022 TERMIS EU (oral)Šećerović A, Ristaniemi A, Cui S, Li Z, Alini M, Weder G, Heub S, Ledroit D, Grad S. Influence of dexamethasone on the interaction between glucocorticoid receptor and SOX9: A molecular dynamics study.
2022 TERMIS EU (oral)Stojceski F, Grasso G, Buetti-Dinh A, Stoddart M, Della Bella E. Composite biomaterial-ink with hyaluronan, collagen and calcium phosphate particles for delivery of chemically modified RNA to promote bone regeneration.
2022 TERMIS EU (oral)van der Heide D, Della Bella E, Yuan H, De Groot-Barrère F, Stoddart MJ, D'Este M. Design of 3D printable supramolecular selfassembling β-sheet peptide-hyaluronic acid hydrogels with immunomodulatory properties.
2022 TERMIS EU (oral)Wychowaniec JK, Bektas EI, Devantay N, Eglin D, D'Este M. A multi-well bioreactor for cartilage tissue engineering.
2022 TERMIS EU (poster)Ladner Y, Armiento A, Stoddart M. Mechano-induced chondrogenesis of human MSCs in a biomaterial: A factorial design of experiment approach.
2022 TERMIS EU (poster)Ladner Y, Armiento A, Stoddart M. Controlled release of bacteriophages for the treatment of multidrug-resistant Pseudomonas aeruginosa bone infection in vitro and in vivo.
2022 VoM (poster)Chittò M, Chen B, Kunisch F, Wychowaniec J, Post V, Zeiter S, Wagemans J, Trampuz A, Gonzales Moreno M, Lavigne R, Moriarty TF. Outcome und inflammatorische Gewebereaktion nach Entfernung winkelstabiler Platten aus PEEK und Titan am proximalen Humerus.
2022 DVSE (oral)Fleischhacker E, Helfen T, Milz S, Saller M, Sprecher C, Siebenbürger G, Gleich J, Böcker W, Ockert B. Einfluss der Knochenmatrix auf die Frakturmorphologie der lateralen Klavikula.
2022 DVSE (oral)Gewiess J, Sprecher C, Milz S, Gleich J, Helfen T. Simulating vertebroplasty using a continuum model based on the Theory of Porous Media and its validation.
2022 GAMM (oral)Trivedi Z, Gehweiler D, Wychowaniec J, Wagner A, Gueorguiev B, Ricken T, Röhrle O. cmRNAbone project: 3D printed-matrix assisted chemically modified RNAs bone regenerative therapy for trauma and osteoporotic patients. 2022 ESB (Biomaterials) (oral) D'Este M, van der Heide D, Amédée J, Stoddart MJ.
Physico-chemical and immunoregulatory characterization of polyelectrolytes coatings from a bacterial exopolysaccharide.
2022 ESB (Biomaterials) (poster)Bagnol R, O'Mahony L, Moriarty TF, Eglin D. Influence of biomaterials surface composition and topography on the activation of neutrophils.
2022 ESB (Biomaterials) (poster)Bektas EI, Wesdorp MA, Wychowaniec JK, Miklosic G, D'Este M. polyionic complexes as a new building block to develop a novel bioink to model the intervertebral disc.
2022 ESB (Biomaterials) (poster)De Oliveira S, Miklosic G, D'Este M, Grastilleur S, Véziers J, Hélary C. Collagen/hyaluronan Hyaluronan-collagen composite bioink for the printing of nucleus pulposus-like structures.
2022 ESB (Biomaterials) (poster)Miklosic G, De Oliveira S, Grastilleur S, Hélary C, Ferguson SJ, D'Este M. 3D printable supramolecular self-assembling β-sheet peptide and tyramine-modified hyaluronan hydrogels with immunomodulatory properties.
2022 ESB (Biomaterials) (poster)Wychowaniec JK, Edwards-Gayle CJC, Bektas EI, Eglin D, D'Este M. Dual application of bacteriophages and meropenem using microbead-loaded hydrogel for treatment of multidrug-resistant Pseudomonas aeruginosa in a mouse model of bone infection.
2022 ICORS (oral)Chittò M, Chen B, Kunisch F, Wychowaniec J, Onsea J, Post V, Richards RG, Zeiter S, Wagemans J, Trampuz A, D'Este M, Gonzales Moreno M, Lavigne R, Moriarty TF. Anatomical analysis of different helical plate designs for distal femoral fracture fixation.
2022 ICORS (oral)Gehweiler D, Pastor T, Beeres FJP, Kastner P, Migliorini F, Nebelung S, Scaglioni MF, Souleiman F, Link B-C, Babst R, Gueorguiev B, Knobe M. In vitro methodology for systematic CT investigation of the periclavicular space.
2022 ICORS (oral)Gehweiler D, Pastor T, Gueorguiev B, Jaeger M, Lambert S. Increasing local cell density by sound to engineer vascularized bone constructs.
2022 ICORS (oral)Guex AG, Krattiger LA, Carrara BM, Alini M, Ehrbar M, Serra T. Validation of a novel device for digitally enhanced hands-on surgical training of intramedullary nail distal interlocking.
2022 ICORS (oral)Pastor T, Knobe M, Kastner P, Souleiman F, Pastor T, Gueorguiev B, Windolf M, Buschbaum J.
Light-curable fracture fixation solution comparable with metal plates in torsion.
2022 ICORS (oral)Schwarzenberg P, Colding-Rasmussen T, Hutchison DJ, Mischler D, Horstmann P,
Petersen MM, Malkoch M, Wong C, Varga P.Ex vivo organ model and sample holder for intervertebral disc studies in a new generation of multiaxial bioreactors.
2022 ICORS (oral)Šećerović A, Ristaniemi A, Cui S, Li Z, Alini M, Weder G, Heub S, Ledroit D, Grad S. Bone defect healing using the induced-membrane technique after chronically infected non-union in a novel rabbit model.
2022 ICORS (oral)Siverino C, Arens D, Zeiter S, Richards RG, Moriarty TF.
Better anteroposterior translation and axial tibiofibular joint stability provided by novel dynamic screw-suture stabilization system for syndesmotic repair.
2022 ICORS (oral)Souleiman F, Zderic I, Pastor T, Gehweiler D, Gueorguiev B, Galie J, Kent T, Tomlinson M, Schepers T, Swords M. Cartilage and subchondral bone changes in osteoarthritis can be detected quantitatively using in vivo imaging.
2022 ICORS (poster)Antonacci P, Dauwe J, Varga P, Ciric D, Gehweiler D, Gueorguiev B, Mys K. Biomechanical evaluation of an allograft fixation system for ACL reconstruction in comparison to the interference screw.
2022 ICORS (poster)Benca E, van Knegsel K, Zderic I, Caspar J, Strassl A, Hirtler L, Fuchssteiner C, Gueorguiev B,
Windhager R, Widhalm H, Varga P.Biomechanical investigation of fracture loads and patterns of the odontoid process.
2022 ICORS (poster)Benca E, van Knegsel K, Zderic I, Caspar J, Strassl A, Hirtler L, Fuchssteiner C, Gueorguiev B,
Windhager R, Widhalm H, Varga P.Peri anesthetic hypothermia in rodents: a factor to consider for accurate and reproducible outcomes in orthopedic device-related infection studies.
2022 ICORS (poster)Constant C, Moriarty TF, Arens D, Pugliese B, Zeiter S. Anatomical analysis of different helical plate designs for proximal humeral shaft fracture fixation.
2022 ICORS (poster)
Pastor T, Kastner P, Souleiman F, Gehweiler D, Link B-C, Beeres F, Babst R, Gueorguiev B,
Knobe M.
Anterior variable-angle locked plating versus tension band wiring of simple and complex patella fractures – a biomechanical study.
2022 ICORS (poster)Stoffel K, Zderic I, Pastor T, Woodburn W, Castle R, Penman J, Sanchez ES, Gueorguiev B,
Sommer C.Influence of knot number on holding capacity of two high strength sutures in different media - a biomechanical analysis.
2022 ICORS (poster)van Knegsel K, Hsu C-E, Huang K-C, Benca E, Pastor T, Gueorguiev B, Varga P, Knobe M. Artificially induced peri-implant inflammation around mechanically loaded Zirconia and Titanium implants.
2022 MTE Implants (oral)Wolf S, Sprecher CM, Milz S, Woelfler H, Gahlert M, Janner S, Meng B, Cochran DL,
Roehling S.Comparative study of particle loads in peri-implant soft tissue over osteosynthesis plates made of CFR-PEEK and titanium.
2022 MTE Implants (poster)Fleischhacker E, Sprecher CM, Milz S, Wirz R, Zobray R, Parrilli A, Saller MM, Helfen T,
Ockert B.Novel dynamic screw-suture stabilization system for syndesmotic repair provides better anteroposterior translation and axial tibiofibular joint stability – a human cadaveric study.
2022 AOFAS (oral)Swords M, Souleiman F, Zderic I, Pastor T, Gehweiler D, Galie J, Kent TJ, Gueorguiev B,
Tomlinson M, Schepers T.Transforming electronic health records (EHR) of scoliosis patients into clinical registries using natural language processing (NLP) and computer vision methods.
2022 SRS (poster)Yan S, Sagheb E, Constant C, Ramazanian T, Aubin C-E, Sohn S, Kremers HM, Larson AN. Influence of knot number on holding capacity of two high strength sutures in different media - a biomechanical analysis.
2022 AGA (poster)van Knegsel K, Zderic I, Kastner P, Varga P, Gueorguiev B, Knobe M, Pastor T. Physico-chemical characterization of polyelectrolyte coatings composed of a bacterial exopolysaccharide and chitosan.
2022 GR forscht (oral)Bagnol R, O'Mahony L, Moriarty TF, Eglin D. Development of electrochemical nitric oxide microsensors for the real time monitoring of inflammation in chondrocytes.
2022 GR forscht (oral)Belcastro L, Antonacci P, Rocchitta G, Arduini F, Serra PA, Alini M, Grad S, Basoli V. A new strategy for the treatment of staphylococcus aureus fracture-related infections using bacteriophage-derived enzymes and antibiotics.
2022 GR forscht (oral)Chittò M, De Maesschalck V, Wagemans J, Lavigne R, Moriarty TF. Anti-inflammatory and regenerative effects of liraglutide on inflammatory human osteoarthritic chondrocytes in vitro.
2022 GR forscht (oral)
Ciftci Dede E, Li K, Grad S, Alini M, Li Z.
LEGO®-inspired multicomponent 3D-printed bone substitute for personalised facial bone repair.
Wie wir das LEGO®-Prinzip in die Herstellung eines Knochen-Ersatzes eingefügt haben. 2022 GR forscht (oral)Hatt LP, Wirth S, Armiento AR, Pirera ME, Ristaniemi A, Thompson K, Gehweiler D, Eglin D,
Stoddart MJ.
Development of bioprinted osteochondral tissue: an in-vitro model for drug discovery.
2022 GR forscht (oral)Jahangir S, Vecstaudža J, Canciani E, Locs J, Alini M, Serra T.
Developing materials for cartilage regeneration under mechanical load.
2022 GR forscht (oral)Mecchi L, Guex AG, Stoddart M.
Hyaluronan-collagen bioink for the printing of intervertebral disc models.
2022 GR forscht (oral)Miklosic G, De Oliveira S, Grastilleur S, Hélary C, Ferguson SJ, D'Este M.
Combination of the collagen membranes within the LEGO® inspired interlocking system, a new therapeutic alternative for bone regeneration in maxillary defects.
2022 GR forscht (oral)Pirera ME, Hatt LP, Wirth S, Stoddart MJ.
Natural bone inspired 3D printed composite biomaterial-ink composed of hyaluronan, collagen and calcium phosphate particles to promote bone regeneration
2022 GR forscht (oral)van der Heide D, Della Bella E, Huipin Y, de Groot-Barrère F, Stoddart M, D'Este M.
Instability after reverse shoulder prosthesis treatment.
2022 BOTA (oral)Hadzhinikolova M, Enchev D, Baltov A, Gueorguiev B, Rusimov L, Rashkov M.
Shear wave elastography for assessment of m.deltoideus in patients after reverse shoulder prosthesis treatment.
2022 BOTA (oral)Hadzhinikolova M, Enchev D, Baltov A, Gueorguiev B, Rusimov L, Rashkov M.
Benefit of PMMA augmentation of locked plating of unstable proximal humerus fractures – a biomechanical investigation.
2022 BOTA (oral)Zhelev D, Hristov S, Zderic I, Ivanov S, Baltov A, Gueorguiev B. Biomechanical investigation of two configurations for screw fixation of capitellum humeri. 2022 BOTA (poster) Zhelev D, Hristov S, Zderic I, Ivanov S, Baltov A, Gueorguiev B.> Hyaluronan-collagen composite bioink for the printing of nucleus pulposus-like structures.
2022 Biofabrication (oral)Miklosic G, De Oliveira S, Grastilleur S, Hélary C, Ferguson SJ, D'Este M. Fractographic analysis of two different plate designs used for orthopaedic trauma surgery.
2022 ICMCC (oral)Zderic I, Dimitrova R, Petkov V, Sprecher CM, Mischler D, Richards G, Gueorguiev B,
Drenchev L.
Sound programmable vasculature morphogenesis.
2022 TERMIS AP (oral)Serra T, Alini M, Di Marzio N. Reproducing kinematic load in vitro for chondrogenesis studies.
2022 TERMIS AP (oral)Stoddart M.
On the way to a bio-printed intervertebral disc (IVD) model: In vitro evaluation of the interactions of ovine IVD cells with a collagen/hyaluronic acid bio-ink.
2022 TERMIS AP (poster)Le Visage C, Grastilleur S, Humbert P, Miklosic G, Halgand B, Loll F, D'Este M, Hélary C,
Fusellier M, Guicheux J.Cutting edge advancements in septic arthritis in ruminants.
2022 ACVS Surgery Summit (oral)Constant C. Lactate measurement in long bone fractures in cattle. Capillary lactate concentration predicts 30-day post-admission mortality and complications in cattle with long bone fractures.
2022 ACVS Surgery Summit (oral)Constant C, Marchionatti E, Desrochers A, Babkine M, Nichols S.
A sound assembly platform to control tissue organization.
2022 BioMaH (oral)Serra T.
Towards deciphering neutrophils role in the immune response to biomaterials.
2022 BioMaH (oral)Wesdorp MA, Bektas EI, Schwab A, Narcisi R, Eglin D, Stoddart MJ, van Osch GJVM,
D'Este M.
Vergleichende Untersuchung von hoch- und niedrigvirulenten Staphylococcus aureus Isolaten bei frakturassoziierten Infektionen im Mausmodell.
2022 DKOU (oral)
Bärtl S, Gens L, Zeiter S, Rupp M, Moriarty F, Alt V.
Cementless femoral stem revision in total hip arthroplasty- the periprosthetic clamshell fracture. A biomechanical investigation.
2022 DKOU (oral)
Kastner P, Zderic I, Gueorguiev B, Richards G, Schauer B, Hipmaier G, Gotterbarm T,
Schopper C.
Low-profile dual mini-fragment plating of diaphyseal clavicle fractures. A biomechanical comparative analysis.
2022 DKOU (oral)
Pastor T, Knobe M, van de Wall B, Zderic I, Rompen I, Link B, Babst R, Gueorguiev B,
Beeres F.
Die aussagekräftigste Fußposition zur nichtinvasiven Detektion einer Verletzung der Syndesmose: Eine 3D-Analyse.
2022 DKOU (oral)
Souleiman F, Heilemann M, Hennings R, Hepp P, Gueorguiev B, Richards G, Gehweiler D,
Osterhoff G.
Ein neues dynamisches Implantatsystem zur Stabilisation des distalen Tibiofibulargelenkes: verbesserte anteroposteriore und axiale Translation bei der längeninstabilen Verletzung der Syndesmose.
2022 DKOU (oral)Souleiman F, Zderic I, Pastor T, Gehweiler D, Gueorguiev B, Galie J, Kent T, Tomlinson M,
Schepers T, Swords M.
Einfluss der belasteten und unbelasteten Fußstellung auf die Stellung des distalen Tibiofibulargelenks - eine dreidimensionale Analyse.
2022 DKOU (oral)
Souleiman F, Heilemann M, Hennings R, Hepp P, Richards G, Gueorguiev B, Gehweiler D,
Osterhoff G.
Helical plating of proximal third humeral shaft fractures - a biomechanical comparative study. 2022 DKOU (oral) Zderic I, Pastor T, van Knegsel K, Richards RG, Gueorguiev B, Knobe M.
Anatomical analysis of different helical plate designs for proximal humeral shaft fracture fixation. 2022 DKOU (poster)
Pastor T, Kastner P, Souleiman F, Gehweiler D, Link B, Beeres F, Babst R, Gueorguiev B,
Knobe M.
Glenoidaler Knorpel-Knochenverlust bei Schulterinstabilitäten: Der Verlust der glenoidalen Tiefe und der Konkavität sind relevantere Vorhersagewerte als die Defektgröße.
2022 DKOU (poster)
Souleiman F, Zderic I, Pastor T, Varga P, Richards G, Gueorguiev B, Osterhoff G, Hepp P,
Theopold J.
A reliable predictor of secondary lateral wall fracture following trochanteric fractures - an update.
2022 DKOU (poster)
van Knegsel K, Hsu C-E, Huang K-C, Benca E, Ganse B, Pastor T, Gueorguiev B, Varga P,
Knobe M.
Biomechanical analysis of helical versus straight plating of proximal third humeral shaft fractures.
2022 DKOU (poster)Zderic I, Pastor T, van Knegsel K, Link B, Beeres F, Babst R, Gueorguiev B, Knobe M. -
Peer-reviewed publications
Non-linear explicit micro-FE models accurately predict axial pull-out force of cortical screws in human tibial cortical bone.
J Mech Behav Biomed Mater. 2022;126:105002Ovesy M, Silva-Henao JD, Fletcher JWA, Gueorguiev B, Zysset PK, Varga P. Adaptive local thresholding can enhance the accuracy of HR-pQCT-based trabecular bone morphology assessment.
Bone. 2022;154:116225 (epub 2021; Oct 9)Mys K, Stockmans F, Gueorguiev B, Wyers CE, van den Bergh JPW, van Lenthe GH, Varga P. One size may not fit all: patient-specific computational optimization of locking plates for improved proximal humerus fracture fixation.
J Shoulder Elbow Surg. 2022;31:192-200 (epub 2021; Jul 20)Schader JF, Mischler D, Dauwe J, Richards RG, Gueorguiev B, Varga P. Hyaluronic acid-based interpenetrating network hydrogel as a cell carrier for nucleus pulposus repair.
Carbohydr Polym. 2022:277:118828Guo W, Douma L, Hu MH, Eglin D, Alini M, Secerovic A, Grad S, Peng X, Zou X, D'Este M, Peroglio M. Editorial - Disc Biology Special Issue.
Eur Cell Mater. 2022;43:1-3Vernengo A, Li Z, Grad S.
Volar versus combined dorsal and volar plate fixation of complex intraarticular distal radius fractures with small dorsoulnar fragment - a biomechanical study.
BMC Musculoskelet Disord. 2022;23(1):35Hadzhinikolova M, Zderic I, Ciric D, Barcik JP, Enchev D, Baltov A, Rusimov L, Varga P, Stoffel K, Richards RG, Gueorguiev B, Rashkov M.
Timing of postoperative weightbearing in the treatment of traumatic chondral injuries of the knee in athletes - A systematic review of current concepts in clinical practice. Asia Pac J Sports Med Arthrosc Rehabil Technol. 2022;27:1-8
Rolf S, Kwan C-K, Stoddart M, Li Y, Fu S-C.
RIA versus iliac crest bone graft harvesting: A meta-analysis and systematic review. Injury. 2022;53:286-293 (epub 2021;Oct 15)
van de Wall BJM, Beeres FJP, Rompen IF, Link BC, Babst R, Schoeneberg C, Michelitsch C, Nebelung S, Pape HC, Gueorguiev B, Knobe M.
Functional outcomes before and after implant removal in patients with posttraumatic shoulder stiffness and healed proximal humerus fractures: does implant material (PEEK vs. titanium) have an impact? - a pilot study.
BMC Musculoskelet Disord. 2022;23(1):95Fleischhacker E, Sprecher CM, Milz S, Saller MM, Gleich J, Siebenbürger G, Helfen T, Böcker W, Ockert B.
Skeletal infections: microbial pathogenesis, immunity and clinical management.
Nat Rev Microbiol. 2022;20:385-400Masters EA, Ricciardi BF, de Mesy Bentley KL, Moriarty TF, Schwarz EM, Muthukrishnan G. Angular stable locking in a novel intramedullary nail improves construct stability in a distal tibia fracture model.
Injury. 2022;53:878-884 (epub 2021; Nov 6)Zderic I, Gueorguiev B, Blauth M, Weber A, Koch R, Dauwe J, Schader JF, Stoffel K, Finkemeier C, Hessmann M.
Is intrathoracic rib plate fixation advantageous over extrathoracic plating? A biomechanical cadaver study.
J Trauma Acute Care Surg. 2022;93:574-580 (epub 2021; Oct 22)Mischler D, Schopper C, Gasparri M, Schulz-Drost S, Brace M, Gueorguiev B.
Medial talar resection: how much remains stable?
Eur J Trauma Emerg Surg. 2022;48:3961-3967Hagen JE, Sands AK, Swords M, Rammelt S, Schmitz N, Richards RG, Gueorguiev B, Souleiman F.
Biomechanical comparison of acetabular fracture fixation with stand-alone THA or in combination with plating.
Eur J Trauma Emerg Surg. 2022;48:3185-3192Wenzel L, Sandriesser S, Glowalla C, Gueorguiev B, Perl M, Stuby FM, Augat P, Hungerer S. Percutaneous fixation of intraarticular joint-depression calcaneal fractures with different screw configurations - a biomechanical human cadaveric analysis.
Eur J Trauma Emerg Surg. 2022;48:3305-3315Ivanov S, Stefanov A, Zderic I, Rodemund C, Schepers T, Gehweiler D, Dauwe J, Pastor T, Makelov B, Raykov D, Richards RG, Gueorguiev B. Work intensity and quality of life can be restored following double-level osteotomy in varus knee osteoarthritis.
Knee Surg Sports Traumatol Arthrosc. 2022;epub Mar 10Ihle C, Dorn J, Ateschrang A, Baumgartner H, Herbst M, Döbele S, Histing T, Schröter S, Ahrend MD. Influence of screw head diameter on ex vivo fixation of equine lateral condylar fractures with 5.5 mm cortical screws.
Vet Surg. 2022;51:576-591Constant C, Zderic I, Arens D, Pugliese B, Gehweiler D, Gueorguiev-Rüegg B, Zeiter S. Anatomical analysis of different helical plate designs for distal femoral fracture fixation.
Injury. 2022;53:2636-2641Pastor T, Beeres FJP, Kastner P, Gehweiler D, Migliorini F, Nebelung S, Scaglioni MF, Souleiman F, Link B-C, Babst R, Gueorguiev B, Knobe M. Development and characterization of a predictive microCT-based non-union model in Fischer F344 rats.
Arch Orthop Trauma Surg. 2022;142(4):579-90 (epub 2020; Nov 10)Hildebrand M, Herrmann M, Gieling F, Gehweiler D, Mischler D, Verrier S, Alini M, Zeiter S, Thompson K. Overweight patients benefit from high tibial osteotomy to the same extent as patients with normal weights but show inferior mid-term results.
Knee Surg Sports Traumatol Arthrosc. 2022;30(3):907-17 (epub 2021; Feb 11)Herbst M, Ahrend MD, Grunwald L, Fischer C, Schroter S, Ihle C. Pre-culture of human mesenchymal stromal cells in spheroids facilitates chondrogenesis at a low total cell count upon embedding in biomaterials to generate cartilage microtissues.
Acta Biomater. 2022;143:253-265Staubli F, Stoddart MJ, D'Este M, Schwab A. Engineering strategies for customizing extracellular vesicle uptake in a therapeutic context.
Stem Cell Res Ther. 2022;13(1):129Esmaeili A, Alini M, Eslaminejad MB, Hosseini S. Low-profile dual mini-fragment plating of diaphyseal clavicle fractures. A biomechanical comparative testing.
Clin Biomech. 2022;94:105634Pastor T, Knobe M, van de Wall BJM, Rompen IF, Zderic I, Visscher L, Link B-J, Babst R, Gueorguiev B, Beeres FJP. Optimization of loading protocols for tissue engineering experiments.
Sci Rep. 2022;12(1):5094Ladner YD, Armiento AR, Kubosch EJ, Snedeker JG, Stoddart MJ. Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions.
Pharmacol Ther. 2022;243: 108043Walsh CM, Wychowaniec JK, Brougham DF, Dooley D. Effect of crosslinking strategy on the biological, antibacterial and physicochemical performance of hyaluronic acid and varepsilon-polylysine based hydrogels.
Int J Biol Macromol. 2022;208:995-1008Salma-Ancane K, Sceglovs A, Tracuma E, Wychowaniec JK, Aunina K, Ramata-Stunda A, Nikolajeva V, Loca D. Cartilage decisively shapes the glenoid concavity and contributes significantly to shoulder stability.
Knee Surg Sports Traumatol Arthrosc. 2022;30:3626-3633Souleiman F, Zderic I, Pastor T, Varga P, Helfen T, Richards G, Gueorguiev B, Theopold J, Osterhoff G, Hepp P. Preexisting and treated concomitant ankle instability does not compromise patient-reported outcomes of solitary osteochondral lesions of the talus treated with matrix-induced bone marrow stimulation in the first postoperative year: data from the German Cartilage Registry (KnorpelRegister DGOU).
Knee Surg Sports Traumatol Arthrosc. 2022;30(4):1187-96 (epub 2020; July 31)Ahrend MD, Aurich M, Becher C, Ateschrang A, Schroter S, Walther M, Gottschalk O, Plaass C, Ettinger S, Zinser W, Korner D. Increased tibial tubercle-trochlear groove and patellar height indicate a higher risk of recurrent patellar dislocation following medial reefing.
Knee Surg Sports Traumatol Arthrosc. 2022;30(4):1404-13 (epub 2021; May 25)Ahrend MD, Eisenmann T, Herbst M, Gueorguiev B, Keller G, Schmidutz F, Döbele S, Schröter S, Ihle C. Preoperative skin asepsis protocols using chlorhexidine versus povidone-iodine in veterinary surgery: A systematic review and meta-analysis.
Vet Surg. 2022;51(5):744-752Marchionatti E, Constant C, Steiner A. Translation and emerging functions of non-coding RNAs in inflammation and immunity.
Allergy.
2022;77:2025-2037Della Bella E, Koch J, Baerenfaller K. Tips and tricks to avoid implant failure in proximal femur fractures treated with cephalomedullary nails: a review of the literature.
OTA International. 2022;5(2S):e191Petfield JL, Visscher LE, Gueorguiev B, Stoffel K, Pape H-C. An antibiotic-loaded hydrogel demonstrates efficacy as prophylaxis and treatment in a large animal model of orthopaedic device-related infection.
Front Cell Infect Microbiol. 2022;12Boot W, Foster AL, Guillaume O, Eglin D, Schmid T, D’Este M, Zeiter S, Richards RG, Moriarty TF. Zementaugmentation und Knochenersatz - Materialien und Biomechanik [Cement augmentation and bone graft substitutes-Materials and biomechanics].
Unfallchirurgie. 2022;125:430-435Gueorguiev B, Lenz M. Comparison and optimization of sheep in vivo intervertebral disc injury model.
JOR SPINE. 2022;5:e1198Constant C, Hom WW, Nehrbass D, Carmel E-N, Albers CE, Deml MC, Gehweiler D, Lee Y, Hecht A, Grad S, Iatridis JC, Zeiter S. Der Einfluss von plättchenreichem Plasma auf die simulierte ACT im kniegelenkstypischen Bioreaktor [Influence of platelet-rich plasma, platelet lysate and mechanical loading on chondrogenesis in vitro]
Knie Journal. 2022;4:145-147Pötter N, Westbrock F, Grad S, Alini M, Stoddart MJ, Schmal H, Kubosch D, Salzmann G, Kubosch EJ. Zhang P, Li K, Kamali A, Ziadlou R, Ahmad P, Wang X, Richards RG, Alini M, Basoli V, Li Z, Grad S. The production and application of bacterial exopolysaccharides as biomaterials for bone regeneration.
Carbohydr Polym. 2022;291:119550Bagnol R, Grijpma D, Eglin D, Moriarty TF. Leave it or fix it? How fixation of a small posterior malleolar fragment neutralizes rotational forces in trimalleolar fractures.
Arch Orthop Trauma Surg. 2022;142(6):1031-7 (epub 2021; Jan 28)Evers J, Fischer M, Raschke M, Riesenbeck O, Milstrey A, Gehweiler D, Gueorguiev B, Ochman S. Local bone quality measure and construct failure prediction: a biomechanical study on distal femur fractures.
Arch Orthop Trauma Surg. 2022;142(6):1055-61 (epub 2021; Feb 15)Gehweiler D, Styger U, Gueorguiev B, Colcuc C, Vordemvenne T, Wähnert D. Orthopedic screws insertion simulation with immediate feedback enhances surgical skill.
Clin Biomech. 2022;94:105367 (epub 2021; Apr 27)Keltz E, Fletcher J, Mora AJ, Yavnai N, Gueorguiev-Rüegg B, Keren Y. Unified validation of a refined second-generation HR-pQCT based homogenized finite element method to predict strength of the distal segments in radius and tibia.
J Mech Behav Biomed Mater. 2022;131:105235Schenk D, Indermaur M, Simon M, Voumard B, Varga P, Pretterklieber M, Lippuner K, Zysset P. Functionalized hydrogels for articular cartilage tissue engineering.
Engineering. 2022;13:71-90Zhou L, Guo P, D'Este M, Tong W, Xu J, Yao H, Stoddart MJ, van Osch GJVM, Ki-Wai Ho K, Li Z, Qin L. Fractographic analysis of two different plate designs used for orthopaedic trauma surgery.
Eng Fail Anal. 2022;139:106440Zderic I, Dimitrova R, Petkov V, Sprecher CM, Mischler D, Richards RG, Gueorguiev B, Drenchev L. Is there a correlation between pelvic incidence and orientation of the acetabulum? An analysis based on a three-dimensional statistical model of the pelvic ring.
J Anat. 2022;241:756-764Arand C, Noser H, Kamer L, Gehweiler D, Handrich K, Rommens PM, Wagner D. Effect of weightbearing and foot positioning on 3D distal tibiofibular joint parameters.
Sci Rep. 2022;12(1):9357Souleiman F, Heilemann M, Hennings R, Hepp P, Gueorguiev B, Richards G, Osterhoff G, Gehweiler D. Computed tomography-based investigation on the effects of intravenous bisphosphonate administration on tooth growth in a minipig animal model.
Medicina. 2022;58(6):778Poxleitner P, Voss PJ, Steybe D, Seibert L-M, Zeiter S, Stoddart MJ, Schmelzeisen R, Otto S. Temporomandibular joint osteoarthritis: A review of animal models induced by surgical interventions.
Oral Dis. 2022;epub May 25Zhou J, Ren R, Li Z, Zhu S, Jiang N. Mischler D, Schader JF, Dauwe J, Tenisch L, Gueorguiev B, Windolf M, Varga P. Validity of a novel digitally enhanced skills training station for freehand distal interlocking.
Medicina. 2022;58(6):773Pastor T, Pastor T, Kastner P, Souleiman F, Knobe M, Gueorguiev B, Windolf M, Buschbaum J. The function of CD146 in human annulus fibrosus cells and mechanism of the regulation by TGF-beta.
J Orthop Res. 2022;40(7):1661-71 (epub 2021; Oct 18)Du J, Guo W, Hackel S, Hoppe S, Garcia JP, Alini M, Tryfonidou MA, Creemers LB, Grad S, Li Z. Distance from the magnification device contributes to differences in lower leg length measured in patients with TSF correction.
Arch Orthop Trauma Surg. 2022;142(7):1511-22 (epub 2021; Mar6)Ahrend MD, Rühle M, Springer F, Baumgartner H. Continuous implant load monitoring to assess bone healing status - evidence from animal testing.
Medicina. 2022;58(7):858Windolf M, Varjas V, Gehweiler D, Schwyn R, Arens D, Constant C, Zeiter S, Richards RG, Ernst M. Continuous rod load monitoring to assess spinal fusion status - pilot in vivo data in sheep.
Medicina. 2022;58(7):899Windolf M, Heumann M, Varjas V, Constant C, Ernst M, Richards RG, Wilke H-J, Benneker LM. Cementless femoral stem revision in total hip arthroplasty: The periprosthetic clamshell fracture. A biomechanical investigation.
J Orthop Res. 2022;epub Jun 23Kastner P, Zderic I, Gueorguiev B, Richards G, Schauer B, Hipmair G, Gotterbarm T, Schopper C. Mineralizing coating on 3D printed scaffolds for the promotion of osseointegration.
Front Bioeng Biotechnol. 2022;10Hasan A, Bagnol R, Owen R, Latif A, Rostam HM, Elsharkawy S, Rose FRAJ, Rodríguez-Cabello JC, Ghaemmaghami AM, Eglin D, Mata A. A culture model to analyze the acute biomaterial-dependent reaction of human primary neutrophils in vitro.
Bioact Mater. 2023;20:627-37Wesdorp MA, Schwab A, Bektas EI, Narcisi R, Eglin D, Stoddart MJ, Van Osch GJVM, D'Este M. Neoepitope fragments as biomarkers for different phenotypes of intervertebral disc degeneration.
JOR Spine. 2022;5:e1215Cui S, Li W, Teixeira GQ, Neidlinger-Wilke C, Wilke H-J, Haglund L, Ouyang H, Richards RG, Grad S, Alini M, Li Z. Comminuted intraarticular calcaneal fractures: Multiplanar VA locked plating and interlocked nailing incorporate longitudinal strut and provide superior stability – a biomechanical cadaveric study.
Injury. 2022;53:3543-3552Stefanov A, Ivanov S, Zderic I, Baltov A, Rashkov M, Gehweiler D, Richards G, Gueorguiev B, Enchev D. Sound-based assembly of a microcapillary network in a saturn-like tumor model for drug testing.
Mater Today Bio. 2022;16:100357Di Marzio N, Ananthanarayanan P, Guex AG, Alini M, Riganti C, Serra T Peri-anesthetic hypothermia in rodents: A factor to consider for accurate and reproducible outcomes in orthopedic device-related infection studies.
J Orthop Res. 2022;epub Jun 18Constant C, Moriarty TF, Arens D, Pugliese B, Zeiter S. Interleukin-1 receptor antagonist enhances the therapeutic efficacy of a low dose of rhBMP-2 in a weight-bearing rat femoral defect model.
Acta Biomater. 2022;149:189-197Lackington WA, Gehweiler D, Zhao E, Zderic I, Nehrbass D, Zeiter S, Gonzalez-Vazquez A, O'Brien FJ, Stoddart MJ, Thompson K. Artificial intelligence accurately detects traumatic thoracolumbar fractures on sagittal radiographs.
Medicina (Kaunas). 2022;58(8):998Sánchez Rosenberg G, Cina A, Schiró GR, Giorgi PD, Gueorguiev B, Alini M, Varga P, Galbusera F, Gallazzi E. Biomechanical determination of fracture loads and patterns of the odontoid process.
Spine (Phila Pa 1976). 2022;47:1212-1220Benca E, Zderic I, van Knegsel KP, Caspar J, Hirtler L, Fuchssteiner C, Strassl A, Gueorguiev B, Widhalm H, Windhager R, Varga P. Ankle joint pressure in supination-external rotation injuries: a biomechanical study in an unrestrained cadaver model.
Foot Ankle Spec. 2022;15(4):330-7 (epub 2020; Sept 2)Fösel AC, Seidel A, Attinger MC, Zderic I, Gueorguiev B, Krause FG. Surgical technique and comparison of autologous cancellous bone grafts from various donor sites in rats.
J Orthop Res. 2022;epub Aug 11Gens L, Marchionatti E, Steiner A, Stoddart MJ, Thompson K, Mys K, Zeiter S, Constant C. Toward the Next Generation of Spine Bioreactors: Validation of an Ex Vivo Intervertebral Disc Organ Model and Customized Specimen Holder for Multiaxial Loading.
ACS Biomater Sci Eng. 2022;8:3969-3976Šećerović A, Ristaniemi A, Cui S, Li Z, Soubrier A, Alini M, Ferguson SJ, Weder G, Heub S, Ledroit D, Grad S. Venous injection of a triphasic calcium-based implant in a sheep model of pulmonary embolism demonstrates minimal acute systemic effects.
Eur Spine J. 2022;31:2812-2821Constant C, Stroncek JD, Zeiter S, Arens D, Nehrbass D, Gehweiler D, Menzel U, Benneker LM, Hill RS, Albers CE. Standard in vitro evaluations of engineered bone substitutes are not sufficient to predict in vivo preclinical model outcomes.
Acta Biomater. 2022;epub Aug 18Hatt LP, Armiento AR, Mys K, Thompson K, Hildebrand M, Nehrbass D, Müller WEG, Zeiter S,
Eglin D, Stoddart MJ.
Species variation in the cartilaginous endplate of the lumbar intervertebral disc.
JOR Spine. 2022;5:e1218Li Y-H, Wu H-L, Li Z, Li B-B, Zhu M, Chen D, Ye F-H, Yu B-S, Huang Y-C.
3D printing of inorganic-biopolymer composites for bone regeneration.
Biofabrication. 2022;14:042003van der Heide D, Cidonio G, Stoddart M, D'Este M.
Protocol for a systematic review of good surgical practice guidelines for experimental rodent surgery.
BMJ Open Science. 2022;6(1):e100280Gantenbein F, Buchholz T, Wever KE, Ritskes Hoitinga M, Zeiter S, Seebeck P.
Intradiscal injection of human recombinant BMP-4 does not reverse intervertebral disc degeneration induced by nuclectomy in sheep.
J Orthop Translat. 2022;37:23-36
Du J, Garcia JP, Bach FC, Tellegen AR, Grad S, Li Z, Castelein RM, Meij BP, Tryfonidou MA,
Creemers LB.
Osteochondral explants for diarthrodial joint diseases: bridging the gap between bench and bedside.
Eur Cell Mater. 2022;44:74-98
Li KH, Zhu Y, Zhang PH, Alini M, Grad S, Li Z.
Influence of axial limb rotation on radiographic lower limb alignment: a systematic review.
Arch Orthop Trauma Surg. 2022;142(11):3349-66 (epub 2021; Oct 1)Ahrend MD, Baumgartner H, Ihle C, Histing T, Schröter S, Finger F.
Emerging magnetic fabrication technologies provide controllable hierarchically-structured biomaterials and stimulus response for biomedical applications.
Adv Sci (Weinh). 2022;epub Oct 13:e2202278
Wychowaniec JK, Brougham DF.
Hierarchical porous metal-organic gels and derived materials: from fundamentals to potential applications.
Chem Soc Rev. 2022;epub Oct 21Wychowaniec JK, Saini H, Scheibe B, Dubal DP, Schneemann A, Jayaramulu K.
A novel technique for treatment of metaphyseal voids in proximal humerus fractures in elderly patients.
Medicina (Kaunas). 2022;58(10):1424
Hristov S, Visscher L, Winkler J, Zhelev D, Ivanov S, Veselinov D, Baltov A, Varga P, Berk T, Stoffel K, Kralinger F, Gueorguiev B.
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Theses and Dissertations
In vitro response of deep zone chondrocytes to hypertrophic stimuli.
2022 ETH Zürich (S. Grad, A. Schwab, S. Schürle-Finke) – MSc ETH HSTMeyer A. One-staged locked externalized plating for the treatment of unstable proximal metadiaphyseal tibial fractures
2022 Medical University – Varna (I. Raykov, B. Gueorguiev) - PhDMakelov B. Effect of resting period and number of deformations in mechanically driven mesenchymal progenitor cell differentiation.
2022 ETH Zürich (S. Verrier, K. Maniura) – MSc ETH HSTEnzmann S. Effect of short time of stimulation on endochondral MSC differentiation.
2022 ZHAW (S. Verrier, R. Eibl-Schindler) – Master ZHAWKeller J.
2021
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Abstracts published in journals
Simulating vertebroplasty: A biomechanical challenge.
Proc Appl Math Mech. 2021;20(1):e202000313 (conference paper GAMM 2020 virtual / oral)Trivedi Z, Bleiler C, Gehweiler D, Gueorguiev-Rüegg B, Ricken T, Wagner A, Röhrle O.
Evidence-based generic asian pelvic bone models for research, development, and teaching using CT-based 3D statistical modelling.
Orthopaedic Proceedings. 2021;103-B(Suppl 4):12 (EORS 2019 / oral)Ahrend MD, Noser H, Shanmugam R, Kamer L, Burr F, Hügli H, Zaman TK, Richards RG,
Gueorguiev B.
Automated electromechanical system designed to investigate the effect of local mechanical conditions on fracture healing progression.
Orthopaedic Proceedings. 2021;103-B(Suppl 4):7 (EORS 2019 / oral)Barcik J, Ernst M, Freitag L, Dlaska CE, Drenchev L, Todorov S, Gueorguiev B, Skulev H,
Zeiter S, Epari D, Windolf M.
Continuous monitoring of fracture healing to analyze short-term response of bone repair tissue to mechanical stimulation.
Orthopaedic Proceedings. 2021;103-B(Suppl 4):11 (EORS 2019 / oral)Barcik J, Ernst M, Balligand M, Dlaska CE, Drenchev L, Todorov S, Gueorguiev B, Skulev H, Zeiter S, Epari D, Windolf M.
Local non-viral gene delivery to immunomodulate and enhance fracture healing.
Orthopaedic Proceedings. 2021;103-B(Suppl 4):13 (EORS 2019 / oral)Gomez-Sierra MA, Lackington WA, Alini M, Thompson K. Biphasic plating: In vivo study on a novel fixation concept to enhance mechanobiological fracture healing.
Orthopaedic Proceedings. 2021;103-B(Suppl 4):14 (EORS 2019 / oral)Hofmann-Fliri L, Epari D, Schwyn R, Zeiter S, Windolf M. A novel 3D in vitro model for osteomyelitis-associated staphylococcal abscess communities.
Orthopaedic Proceedings. 2021;103-B(Suppl 4):20 (EORS 2019 / oral)Hofstee MI, Riool M, Thompson K, Stoddart MJ, Zaat SAJ, Moriarty TF. Externalized locked plating of unstable proximal tibial fractures can provide sufficient stability under partial weightbearing: A finite element study.
Orthopaedic Proceedings. 2021;103-B(Suppl 4):22 (EORS 2019 / oral)Makelov B, Silva JD, Apivatthakakul T, Gueorguiev B, Varga P. Improving fixation techniques of proximal humerus fractures by means of finite element analysis.
Orthopaedic Proceedings. 2021;103-B(Suppl 4):19 (EORS 2019 / oral)Mischler D, Schader JF, Windolf M, Varga P. Influence of different Lisfranc ligament injuries on CT findings.
Orthopaedic Proceedings. 2021;103-B(Suppl 4):6 (EORS 2019 / oral)Penev P, Zderic I, Qawasmi F, Mosheiff R, Knobe M, Krause F, Richards RG, Raykov D, Better stability and more predictive fixation of the femoral neck system versus two Hansson pins in Pauwels II femoral neck fractures: A biomechanical study.
Orthopaedic Proceedings. 2021;103-B(Suppl 4):23 (EORS 2019 / oral)Schopper C, Zderic I, Menze J, Muller D, Rocci M, Knobe M, Shoda E, Richards RG, Gueorguiev B, Stoffel K.
Artificial intelligence can accurately and reliably detect traumatic thoracolumbar fractures on sagittal radiographs.
Brain and Spine. 2021;1(Suppl 1):100046 (2021 EuroSpine / oral)Gallazzi E, Sanchez Rosenberg G, Galbusera F, Varga P, Gueorguiev B, Alini M, Schirò GR, Giorgi PD, Cina A.
Chondroitinase versus papain digestion leads to different outcome for in vitro simulation of degenerated discs.
Brain and Spine. 2021;1(Suppl 1):100008 (2021 EuroSpine / oral)Jansen JU, Teixeira GQ, Vernengo A, Grad S, Neidlinger-Wilke C, Wilke H-J. Biomechanical comparison of two fixation techniques for B2 fractures of the sacrum according to the AO Spine Sacral classification system.
Global Spine J. 2021;11(2 Suppl):145S (Global Spine Congress / oral)Lodde M, Katthagen C, Schopper C, Zderic I, Richards RG, Gueorguiev B, Riesenbeck O, Raschke M, Hartensuer R. Mesenchymal stem cell secretome: a potential anabolic and immunomodulatory therapy for early intervertebral disc degeneration.
Global Spine J. 2021;11(2 Suppl):102S-3S (Global Spine Congress / oral)Wangler S, Kamali A, Wapp C, Wuertz-Kozak K, Häckel S, Fortes C, Benneker LM, Haglund L, Richards RG, Alini M, Peroglio M, Grad S.
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Books and book chapters
Preclinical models of infection in bone and joint surgery.
In: Zimmerli W, editor. Bone and joint infections: From microbiology to diagnostics and treatment. Second Edition.
Wiley; 2021. p. 99-115Constant C, Calabro L, Metsemakers W-J, Richards RG, Moriarty TF. -
Conference presentations
Digitalized aftercare in orthopaedics.
DDF 2021 virtual (oral)Richards RG, Ernst M.
3D printed annulus fibrosus tissue engineering scaffolds with multiscale, uniaxial surface topographies that promote the spatial control of cell density and alignment.
2021 ORS virtual (oral)Kluser N, Sprecher C, Häckel S, Albers C, Li Z, Alini M, Grad S, Eglin D, Vernengo A.
Neoepitope peptides biomarker for different types of intervertebral disc degeneration.
2021 ORS virtual (oral)Cui S, Li W, Teixeira G, Neidlinger-Wilke C, Wilke H-J, Richards RG, Alini M, Grad S, Li Z.
Anti-inflammatory and regenerative effects of small molecules for osteoarthritis – in vitro and ex vivo evaluation.
2021 ORS virtual (oral)Zhang P, Basoli V, Wang X, Alini M, Grad S, Li Z.
Can the COX-2 inhibitor Celecoxib influence discogenic pain signals? An in vitro study with inflamed annulus fibrosus cells.
2021 ORS virtual (oral)Häckel S, Häne S, Eglauf J, Ma J, Li Z, Pfannkuche JJ, Peroglio M, Hoppe S, Benneker LM, Lang GM, Alini M, Grad S.
Emerging methods for 3-dimensional volume interrogation of Staphylococcus aureus pathogenesis in the osteocyte canalicular network.
2021 ORS virtual (oral)de Mesy Bentley KL, Galloway CA, Muthukrishnan G, Echternacht SR, Masters EA, Zeiter S, Leckenby JI, Schwarz EM.
Mesenchymal stem cell secretome: A potential anabolic and immunomodulatory therapy for modulation of early intervertebral disc degeneration.
2021 ORS virtual (oral)Wangler S, Kamali A, Wapp C, Wuertz-Kozak K, Häckel S, Fortes C, Benneker LM, Haglund L, Richards RG, Alini M, Peroglio M, Grad S.
A 3-dimensional in vitro Staphylococcus aureus abscess community model.
2021 KNVM & NVMM virtual (oral)Hofstee MI, Riool M, Terjajevs I, Thompson K, Stoddart MJ, Zaat SAJ, Moriarty T.F.
Angular stable locking in a novel intramedullary nail improves construct stability in a distal tibia fracture model.
2021 GOMTS virtual (poster)Gueorguiev B, Zderic I, Blauth M, Weber A, Koch R, Dauwe J, Schader J, Stoffel K, Finkemeier C, Hessmann M.
Biomechanical human cadaveric investigation of intrathoracic versus extrathoracic rib fracture plating.
2021 GOMTS virtual (poster)Mischler D, Schopper C, Gasparri M, Schulz-Drost S, Brace M, Gueorguiev B.
Biomechanical analysis of recently released cephalomedullary nails for trochanteric femoral fracture fixation in a human cadaveric model.
2021 GOMTS virtual (poster)Pastor T, Zderic I, Gehweiler D, Knobe M, Gueorguiev B.
Improved construct stability after angular stable intramedullary nailing of distal tibia fractures – a biomechanical study.
2021 GOMTS virtual (poster)Zderic I, Caspar J, Blauth M, Weber A, Koch R, Stoffel K, Finkemeier C, Hessmann M, Gueorguiev B.
Effect of nanoparticle-based mRNA delivery on modulation of inflammation in an osteochondral inflammation model.
2021 OARSI Connect virtual (poster)Basoli V, Li Z, Traweger A, Sanchez J, Plank C, Rip J, Alini M, Grad S.
Can the COX-2 inhibitor Celecoxib influence discogenic pain signals? An in vitro study with inflamed annulus fibrosus cells.
2021 ISSLS virtual (poster)Häckel S, Häne S, Eglauf J, Ma J, Li Z, Pfannkuche JJ, Peroglio M, Hoppe S, Benneker LM, Lang GM, Alini M, Grad S.
Staphylococcus aureus abscess communities and myeloid-derived suppressor cells: in vivo and in vitro studies.
2021 WIRM digital (oral)Hofstee MI, Riool M, Gieling F, Stenger V, Constant C, Nehrbass D, Heider A, Zeiter S,
Richards RG, Zaat SAJ, Moriarty TF.Titanium wear particles exacerbate implant-related osteolysis and decrease efficacy of antibiotic therapy.
2021 WIRM digital (poster)Siverino C, Freitag L, Arens D, Eberli U, Stadelmann V, Richards RG, Stoddart MJ, Moriarty TF, Thompson K.
Mechanisms of bone regeneration.
2021 WIRM digital (oral)Stoddart M.
Butyrate and antibiotics affect local and systemic processes relevant for bone healing.
2021 WIRM digital (poster)Wallimann A, Magrath W, Thompson K, Pugliese B, Akdis CA, Richards RG, Hernandez CJ, O'Mahony L, Moriarty TF.
Biomechanical analysis of recently released cephalomedullary nails for trochanteric femoral fracture fixation in a human cadaveric model.
2021 EFORT virtual (poster)Pastor T, Zderic I, Gehweiler D, Knobe M, Gueorguiev B.
Improved construct stability after angular stable intramedullary nailing of distal tibia fractures. A biomechanical study.
2021 EFORT virtual (oral)Zderic I, Caspar J, Blauth M, Weber A, Koch R, Stoffel K, Finkemeier C, Hessmann M, Gueorguiev B, editors.
Mechanical evaluation of two hybrid locking plate designs for canine pancarpal arthrodesis.
2021 ECVS online (oral)Zderic I, Varga P, Styger U, Drenchev L, Gueorguiev B, Asimus E, Saunders B, Kowaleski M, Boudrieau RJ, Dejardin L.
Mechanical evaluation of two hybrid locking plate designs for canine pancarpal arthrodesis under fatigue loading.
2021 ECVS online (oral)Zderic I, Varga P, Styger U, Drenchev L, Gueorguiev B, Asimus E, Saunders B, Kowaleski M, Boudrieau RJ, Dejardin L.
Computationally optimized implants improve biomechanical fixation stability of complex proximal humerus fractures.
2021 ES Biomech online (oral)Mischler D, Schader J, Dauwe J, Gueorguiev B, Varga P.
Trabecular microstructure can be quantified with Xtremect more accurately using adaptive thresholding.
2021 ES Biomech online (oral)Mys K, Stockmans F, Gueorguiev B, Neumann V, Wyers CE, van den Bergh JPW,
van Lenthe GH, Varga P.Prediction of screw perforation in the proximal humerus using micro finite element analyses.
2021 ES Biomech online (oral)Panagiotopoulou V, Ovesy M, Gueorguiev B, Richards RG, Zysset P, Varga P.
Biomechanical analysis of cephalomedullary nails for trochanteric femoral fracture fixation.
2021 ES Biomech online (oral)Pastor T, Zderic I, Gehweiler D, Knobe M, Gueorguiev B.
Could patient-specific locking plates improve primary stability of proximal humerus fracture fixation?
2021 ES Biomech online (oral)Schader JF, Mischler D, Dauwe J, Gueorguiev B, Varga P.
Improved stability of distal tibia fractures after angular stable intramedullary nailing – a biomechanical study.
2021 ES Biomech online (oral)Zderic I, Caspar J, Blauth M, Weber A, Koch R, Stoffel K, Finkemeier C, Hessmann M,
Gueorguiev B.In-silico and experimental deformation analysis of two hybrid plate designs for canine pancarpal arthrodesis.
2021 ES Biomech online (oral)Zderic I, Varga P, Styger U, Gueorguiev B, Drenchev L, Asimus E, Saunders B, Kowaleski M, Boudrieau RJ, Déjardin L.
Pilot hole overdrilling increases screw perforation risk in locked plating of complex proximal humerus fractures.
2021 ES Biomech online (posterBurkhard B, Schopper C, Ciric D, Mischler D, Gueorguiev B, Varga P.
Fatigue life assessment of two hybrid plate designs for canine pancarpal arthrodesis.
2021 ES Biomech online (poster)Zderic I, Varga P, Styger U, Gueorguiev B, Drenchev L, Asimus E, Saunders B, Kowaleski M, Boudrieau RJ, Déjardin L.
Short-chain fatty acids and antibiotics affect local and systemic processes relevant for bone healing.
2021 World Microbe Forum online (poster)Wallimann A, Magrath W, Thompson K, Pugliese B, Akdis CA, Richards RG, Hernandez CJ, O'Mahony L, Moriarty TF.
Short-chain fatty acids and antibiotics affect local and systemic processes relevant for bone healing.
2021 Gut-Bone Axis Meeting virtual (oral)Wallimann A, Magrath W, Thompson K, Pugliese B, Akdis CA, Richards RG, Hernandez CJ, O'Mahony L, Moriarty TF.
Impact of Rifampicin levofloxacin on gut microbiome and Short-Chain Fatty Acid production in mice with bone fracture: consequences for bone health.
2021 ECCMID online (poster)Wallimann A, Magrath W, Thompson K, Pugliese B, Akdis CA, Richards RG, Hernandez CJ, O'Mahony L, Moriarty TF.
Impact of UV, Ethylene oxide and X-ray sterilization on implantable glucose biosensors.
2021 Biosensors online (poster)Zuncheddu D, Siverino C, Rocchitta G, Generelli S, Kurth F, Serra PA, Moriarty TF, Alini M, Grad S, Basoli V.
Micro-extrusion induced orientation of collagen fibrils embedded in hyaluronan and bioinks chondrogenic property.
2021 ES Biomat virtual (oral)D'Este M, Schwab A, Eglin DO, Staubli F.
IL-1 receptor antagonist enhances rhBMP-2-induced new bone formation during femoral fracture healing in rats.
2021 ES Biomat virtual (oral)Lackington WA, Gehweiler D, Zderic I, Nehrbass D, Zeiter S, González-Vázquez A, O'Brien F, Stoddart M, Thompson K.
Composite biomaterial-ink based on hyaluronan and nano hydroxyapatite for biofabrication of bone graft substitutes delivering chemically modified RNAs.
2021 ES Biomat virtual (oral)van der Heide D, Della Bella E, Yuan H, De Groot-Barrère F, Stoddart MJ, D'Este M.
Coaxial micro-extrusion of a calcium phosphate ink with aqueous solvents improves printing stability, structure fidelity and mechanical properties.
2021 ES Biomat virtual (poster)Bagnol R, Sprecher C, Peroglio M, Chevalier J, Ligier O, Mahou R, Büchler P, Richards RG, Eglin D.
Toward core-shell 3D printed photonic strain sensing medical device.
2021 ES Biomat virtual (poster)Eglin D, Sprecher C, Marquette C, Courtial EJ.
Dense extracellular matrix derivatives for the bioprinting of nucleus pulposuslike structures.
2021 ES Biomat virtual (poster)Miklosic G, Hélary C, Ferguson SJ, D'Este M.
An improved 2-aminoimidazole based anti-biofilm coating for orthopedic implants: activity, stability, and in vivo biocompatibility.
2021 ES Biomat virtual (poster)Coppola GA, Onsea J, Moriarty TF, Nehrbass D, Constant C, Zeiter S, Aktan MK, Braem A, Van der Eycken EV, Steenackers HP, Metsemakers W-J.
Fabrication of hyaluronan-based matrices functionalized with laminin derived peptides, to sustain cellular adherence and axonal growth in bone regeneration applications.
2021 ES Biomat virtual (poster)Muller Q, Josseline R, van der Heide D, Le-Meins J-F, Garbay B, Stoddart MJ, D'Este M, Amédée J, Oliveira H.
3D Bioprinting of a tissue mimetic hyaluronan bioink containing collagen fibers with controlled orientation.
2021 EuroMat virtual (oral)Schwab A, Staubli F, Eglin D, D'Este M.
Nonunions - just a biomechanical problem?
2021 EORS (oral)Gueorguiev B.
Novel antimicrobial approaches to prevent orthopedic devicerelated infection.
2021 EORS (oral)Richards RG, Moriarty TF, D'Este M.
In vivo preclinical application of an active fixator system for the systematic investigation of the influence of the mechanical environment on fracture healing.
2021 EORS (oral)Barcik J, Ernst M, Buchholz T, Constant C, Zeiter S, Gueorguiev B, Windolf M.
Double plating of unstable distal femoral fractures: Is augmented lateral plating with a helically shaped medial plate biomechanically advantageous over a straight medial plate?
2021 EORS (oral)Gueorguiev B, Zderic I, Pastor T, Gehweiler D, Richards RG, Knobe M.
Biomechanical analysis of recently released cephalomedullary nails for trochanteric femoral fracture fixation in a human cadaveric model.
2021 EORS (oral)Pastor T, Zderic I, Gehweiler D, Richards RG, Knobe M, Gueorguiev B.
Medial helical versus lateral straight plating of distal femoral fractures. A biomechanical comparative study.
2021 EORS (oral)Pastor T, Zderic I, Richards RG, Gueorguiev B, Knobe M.
Traction to optimize intervertebral disc mechanobiology: A bovine organ model feasibility study.
2021 EORS (oral)Soubrier A, Kasper H, Alini M, Jonkers I, Grad S.
Mesenchymal stromal cell spheroids – effect of cell packing and biomaterial composition on chondrogenic differentiation in vitro.
2021 EORS (oral)Staubli F, Stoddart M, D'Este M, Schwab A.
Angular stable intramedullary nailing improves construct stability in a distal tibia fracture model - a biomechanical study.
2021 EORS (oral)Zderic I, Caspar J, Blauth M, Weber A, Koch R, Stoffel K, Finkemeier C, Hessmann M,
Gueorguiev B.Artificial intelligence accurately detects traumatic thoracolumbar fractures on sagittal radiographs.
2021 EORS (oral)Sanchez Rosenberg G, Cina A, Giorgi P, Schiro G, Gueorguiev B, Alini M, Varga P,
Galbusera F, Gallazzi E.Chondrogenic hyaluronan bio-ink containing collagen fibers with controlled orientation modulating cell orientation and morphology.
2021 BIOFAB online (oral)Schwab A, Eglin D, Helary C, Alini M, D'Este M.
Saturn-like vascularized tumor model: combining spheroid with a ring-shaped microvasculature by using sound.
2021 BIOFAB online (oral)Di Marzio N, Ananthanarayanan P, Guex AG, Alini M, Riganti C, Serra T.
Spatial orchestration of large animal DRG multicellular system using sound.
2021 BIOFAB online (oral)Ma J, Eglauf J, Alini M, Serra T.
Biofabrication of bone graft substitutes using a composite biomaterialink based on hyaluronan and nano hydroxyapatite for delivering chemically modified RNAs.
2021 BIOFAB online (oral)van der Heide D, Della Bella E, Yuan H, De Groot-Barrère F, Stoddart MJ, D'Este M.
Temperature-responsive engineered matrices for the spatial positioning and long-term culture of bioprinted cells.
2021 BIOFAB online (poster)Alig G, D'Este M, Grad S, Alini M, Vernengo A.
Extracellular matrix-based bioink for the printing of nucleus pulposus analogues.
2021 BIOFAB online (poster)Miklosic G, Hélary C, Ferguson SJ, D'Este M.
Initial clinical results following one-stage externalized locked plating of multifragmentary proximal tibia fractures
2021 BOTA (oral)Makelov B, Dimitrov N, Raykov D, Gueorguiev B.
How many screws are necessary for plate fixation of the dorsoulnar fragment?
2021 BOTA (poster)Hadzhinikolova M, Zderic I, Ciric D, Barcik J, Enchev D, Rusimov L, Richards RG, Gueorguiev B, Baltov A, Rashkov M.
Improved biomechanical properties of modified 5.5mm cortex screw with larger head size in an equine lateral condylar fracture model.
2021 ACVS surgery summit virtual (oral)Constant C, Zderic I, Arens D, Pugliese B, Gehweiler D, Gueorguiev-Rüegg B, Zeiter S.
A natural biomimetic hydrogel for cartilage regeneration.
2021 SSB+RM YSS (oral)Guo P, Vernengo A, Miklosic G, D'Este M, Grad S, Alini M, Li Z.
Saturn-like vascularized tumor model: combining spheroid with a ring-shaped microvasculature by using sound
2021 SSB+RM YSS (poster)Di Marzio N, Ananthanarayanan P, Guex AG, Alini M, Riganti C, Serra T.
Sound induced morphogenesis: chondrogenic differentiation of hMSC driven by acoustic stimulation.
2021 SSB+RM YSS (poster)Mecchi L, Guex AG, Alini M, Serra T.
The influence of mesenchymal stromal cells secretome on nucleus pulposus cells exposed to a proinflammatory environment.
2021 SSB+RM YSS (poster)Nüesch A, Chen Z, Wangler S, Li Z, Grad S.
Bioink from collagen and hyaluronic acid: design and characterization of a cardiovascular-specific formulation for 3D bioprinting.
2021 SSB+RM YSS (poster)Palladino S, Schwab A, Copes F, D'Este M, Candiani G, Mantovani D.
LagLoc - a new surgical technique for locking plate systems.
2021 OTA (poster)Triana M, Gueorguiev B, Sommer C, Stoffel K, Agarwal Y, Zderic I, Helfen T, Krieg JC, Krause F, Knobe M, Richards RG, Lenz M.
Pelvic incidence und acetabuläre Orientierung - eine Subgruppenanalyse basierend auf einem 3D statistischen Modell des Beckenrings.
2021 DKOU (oral)Arand C, Wagner D, Kamer L, Gehweiler D, Noser H, Handrich K, Rommens P.
Posttraumatische Schultersteife nach winkelstabiler Plattenosteosynthese proximaler Humerusfrakturen. Hat das Implantatmaterial einen Einfluss?
2021 DKOU (oral)Fleischhacker E, Milz S, Sprecher C, Gleich J, Siebenbürger G, Helfen T, Böcker W, Ockert B.
Die modulierende Wirkung des Cyclooxygenase-2 Inhibitors Celecoxib auf diskogenen Schmerz - eine in vitro Studie mit humanen Annulus fibrosus Zellen.
2021 DKOU (oral)Häckel S, Häne S, Eglauf J, Ma J, Pfannkuche J, Hoppe S, Albers C, Grad S.
Kranial verankerte Pfanne oder Platte und Pfanne bei Azetabulumfrakturen des vorderen Pfeilers? Ein biomechanischer Vergleich.
2021 DKOU (oral)Wenzel L, Sandriesser S, Glowalla C, Gueorguiev-Rüegg B, Perl M, Stuby F, Augat P, Hungerer S.
Biomechanische Analyse von Marknägeln zur Fixierung von pertrochantären Femurfrakturen.
2021 DKOU (poster)Pastor T, Zderic I, Gehweiler D, Richards RG, Gueorguiev B, Knobe M.
Old battle with new implant systems – biomechanical comparison of intramedullary versus extramedullary fixation concepts of stable pertrochanteric fractures.
2021 DKOU (poster)Schader JF, Zderic I, Dauwe J, Sommer C, Gueorguiev B, Stoffel K.
Angiotensin II type 1, type 2, and MAS receptors are present in Human Nucleus Pulposus Cells and associated with inflammatory processes.
2021 DKOU (oral)Saravi B, Basoli V, Alini M, Grad S, Südkamp N, Schmal H, Li Z, Lang G.
Regenerative rehabilitation: from proteins to patients.
2021 TERMIS world congress digital (oral)Stoddart M.
LEGO®-inspired microporous scaffolds for personalised mandibular bone repair.
2021 TERMIS world congress digital (oral)
Hatt LP, Wirth S, Thompson K, Mys K, Gehweiler D, Eglin D, Stoddart MJ, Armiento AR.
Innovative bioink from collagen and hyaluronic acid with tunable rheological and biological properties for cardiovascular 3D bioprinting.
2021 TERMIS world congress digital (oral)Palladino S, Schwab A, D'Este M, Copes F, Candiani G, Mantovani D.
Losartan suppresses TNF-alpha induced inflammatory response and degeneration of human nucleus pulposus cells.
2021 TERMIS world congress digital (oral)Saravi B, Pfannkuche J, Häckel S, Alini M, Grad S, Südkamp N, Schmal H, Kubosch D, Li Z, Lang G.
Effect of biomaterial composition on MSC chondrogenesis embedded in a hyaluronan composite containing collagen fibrils.
2021 TERMIS world congress digital (oral)Schwab A, Staubli F, Eglin D, D'Este M, editors.
Ex vivo migration of chondrocytes - cell invasion into acellular biomaterials filled in a cartilage ring model is dependent on biomaterial composition.
2021 TERMIS world congress digital (oral)Schwab A, Wesdorp MA, Loebel C, Levato R, Burdick JA, Malda J, Stoddart M,
van Osch GJVM, Eglin D, D'Este M.Printability and cytocompatibility of a photo-initiator-free bioink based on coumarin-modified hyaluronic acid and gelatin.
2021 TERMIS world congress digital (poster)D'Este M, Beninatto R, Di Lucia A, Staubli F, Schwab A, Galesso D, Pavan M, editors.
Dexamethasone: A friend or a foe in osteogenic differentiation of human BMSCS?
2021 TERMIS world congress digital (poster)Della Bella E, Ahmad P, Buetti-Dinh A, Licandro G, Basoli V, Alini M, Stoddart M.
Dexamethasone regulates circular RNA expression during human bone marrow mesenchymal stromal cells differentiation.
2021 TERMIS world congress digital (poster)Della Bella E, Menzel U, Basoli V, Tourbier C, Alini M, Stoddart MJ.
Development of a 3-dimensional vascularized cancer model via sound induced morphogenesis (SIM).
2021 TERMIS world congress digital (poster)Di Marzio N, Ananthanarayanan P, Guex AG, Alini M, Riganti C, Serra T.
Sound waves and biomaterials to re-create the extracellular matrix.
2021 TERMIS world congress digital (poster)Guex AG, Di Marzio N, Alini M, Serra T.
In vitro and ex vivo screening of small molecule therapeutics for osteoarthritis.
2021 TERMIS world congress digital (poster)Li Z, Zhang P, Basoli V, Alini M, Grad S.
Comparison of different transfection methods for mRNA delivery in articular joint cells.
2021 TERMIS world congress digital (poster)Sturm L, Schwemberger B, Geiger J, Manish A, Dewi HS, Engbersen J, Rip J, Alini M, Traweger A, Grad S, Basoli V.
A composite biomaterial-ink based on hyaluronan and nano hydroxyapatite delivering chemically modified RNA for bone regeneration.
2021 TERMIS world congress digital (poster)van der Heide D, De Groot-Barrère F, Stoddart MJ, D'Este M.
The influence of dynamic physiological loading on an enzyme-induced ex vivo model of intervertebral disc degeneration.
2021 TERMIS world congress digital (poster)Vernengo A, Kluser N, Soubrier A, Gewiess J, Jansen JU, Neidlinger-Wilke C, Wilke H-J, Li Z, Alini M, Grad S.
Development and characterization of a microsensor device for real time oxygen monitoring in 3D tissue engineered constructs.
2021 TERMIS world congress digital (poster)Zuncheddu D, Schwab A, Della Bella E, Generelli S, Kurth F, Serra PA, Rocchitta G, Kasper H, Grad S, Basoli V.
A hydrogel based on decellularized extracellular matrix particles for cartilage regeneration.
2021 eCM cancelled (oral) / abstract publishedGuo P, Mini C, Miklosic G, Vernengo A, D'Este M, Grad S, Alini M, Li Z.
LEGO®-inspired microporous scaffolds for personalised mandibular bone repair.
2021 eCM cancelled (oral) / abstract publishedHatt LP, Wirth S, Ristaniemi A, Thompson K, Eglin D, Stoddart MJ, Armiento AR.
Extracellular matrix-based biomaterial ink for the printing of nucleus pulposus-like structures. 2021 eCM cancelled (oral) / abstract published
Miklosic G, De Oliveira S, Grastilleur S, Hélary C, Ferguson SJ, D'Este M.
Sound waves for the assembly and control of tissues organization.
2021 eCM cancelled (oral) / abstract publishedSerra T.
A culture model to analyze the acute biomaterial-dependent reaction of human primary neutrophils.
2021 eCM cancelled (oral) / abstract publishedWesdorp MA, Schwab A, Eglin D, Narcisi R, van Osch GJVM, D'Este M.
Collagen/hyaluronan polyionic complexes as a new building block to develop a bioink for muskulo-skeletal applications.
2021 eCM cancelled (poster) / abstract publishedDe Oliveira S, Miklosic G, D'Este M, Hélary C.
Collagen/hyaluronan polyionic complexes as a new building block to develop a bioink for muskulo-skeletal applications.
2021 eCM cancelled (poster) / abstract publishedDe Oliveira S, Miklosic G, D'Este M, Hélary C.
Temperature-responsive engineered matrices for spatial positioning and long-term culture of bioprinted cells.
2021 eCM cancelled (poster) / abstract publishedEgger S, Alig G, D'Este M, Grad S, Alini M, Vernengo A.
Liquid crystal hydroxylpropyl cellulose-silicon 3D printed photonic strain sensing structure.
2021 eCM cancelled (poster) / abstract publishedEglin D, Sprecher C, Marquette C, Courtial EJ.
Spatial control over cell assembly by sound: towards a vascularised in vitro engineered osteochondral tissue.
2021 eCM cancelled (poster) / abstract publishedGuex AG, Mecchi L, Alini M, Serra T.
3D printing of osteoinductive and patient specific implant for CMF repair.
2021 eCM cancelled (poster) / abstract publishedGuillaume O, Geven MA, Varjas V, Varga P, Grijpma DW, Eglin D.
3D printed scaffolds with multiscale surface topography inducing three-dimensional cell patterning.
2021 eCM cancelled (poster) / abstract publishedKluser N, Sprecher C, Häckel S, Alini M, Grad S, Eglin D, Vernengo A.
IL-1Ra enhances rhBMP-2-induced new bone formation during femoral fracture healing.
2021 eCM cancelled (poster) / abstract publishedLackington WA, Gehweiler D, Zderic I, Nehrbass D, Zeiter S, González-Vázquez A, O'Brien FJ, Stoddart MJ, Thompson K.
Sound induced multicellular system of dorsal root ganglion cells.
2021 eCM cancelled (poster) / abstract publishedMarani E, Ma J, Alini M, Serra T.
Composite collagen/hyaluronic acid bioink guiding anisotropic in vitro vascular network formation.
2021 eCM cancelled (poster) / abstract publishedPalladino S, Schwab A, Copes F, D'Este M, Candiani G, Mantovani D.
Composite hyaluronic acid and calcium phosphate biomaterial ink for the delivery of chemically modified RNAs for bone regeneration.
2021 eCM cancelled (poster) / abstract publishedvan der Heide D, Della Bella E, Yuan H, De Groot-Barrère F, Stoddart MJ, D'Este M.
A photoinitiator-free hyaluronan bioink with high modularity and printability.
2021 eCM cancelled (poster) / abstract publishedWeber L, Beninatto R, Di Lucia A, Staubli F, Schwab A, Galesso D, Pavan M, D'Este M.
Führt die Augmentation der perkutanen Iliosakralschraube zu besseren biomechanischen Ergebnissen für die Fixierung des hinteren Beckenrings?
[Does cement augmentation of the sacroiliac screw lead to superior biomechanical results for fixation of the posterior pelvic ring?]
2021 DWK (oral)Lodde MF, Raschke MJ, Hartensuer R, Katthagen C, Schopper C, Zderic I, Richards RG, Gueorguiev B.
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Peer-reviewed publications
Small molecule-based treatment approaches for intervertebral disc degeneration: Current options and future directions.
Theranostics. 2021;11(1):27-47Kamali A, Ziadlou R, Lang G, Pfannkuche J, Cui S, Li Z, Richards RG, Alini M, Grad S. Comminuted patellar fractures: The role of biplanar fixed angle plate constructs.
J Orthop Translat. 2021;27:17-24Kfuri M, Escalante I, Schopper C, Zderic I, Stoffel K, Sommer C, Qawasmi F, Knobe M, Richards RG, Gueorguiev B.
Programable active fixator system for systematic in vivo investigation of bone healing processes.
Sensors. 2021;21(1):17Barcik J, Ernst M, Dlaska CE, Drenchev L, Zeiter S, Epari DR, Windolf M.
Biphasic plating improves the mechanical performance of locked plating for distal femur fractures.
J Biomech. 2021;115:110192Epari DR, Gurung R, Hofmann-Fliri L, Schwyn R, Schuetz M, Windolf M. Emerging electron microscopy and 3D methodologies to interrogate Staphylococcus aureus osteomyelitis in murine models.
J Orthop Res. 2021;39(2):376-388de Mesy Bentley KL, Galloway CA, Muthukrishnan G, Echternacht SR, Masters EA, Zeiter S, Schwarz EM, Leckenby JI.
Clinical feasibility of fracture healing assessment through continuous monitoring of implant load.
J Biomech. 2021;110188Ernst M, Baumgartner H, Döbele S, Höntzsch D, Pohlemann T, Windolf M.
Angiotensin II type 1 receptor antagonist Losartan inhibits TNF-α-induced inflammation and degeneration processes in human nucleus pulposus cells.
Applied Sciences. 2021;11(1):417Saravi B, Li Z, Pfannkuche J, Wystrach L, Häckel S, Albers CE, Grad S, Alini M, Richards RG, Lang C, Südkamp N, Schmal H, Lang G. An exopolysaccharide produced by Bifidobacterium longum 35624(R) inhibits osteoclast formation via a TLR2-dependent mechanism.
Calcif Tissue Int. 2021;108(5):654-66Wallimann A, Hildebrand M, Groeger D, Stanic B, Akdis CA, Zeiter S, Richards RG, Moriarty TF, O'Mahony L, Thompson K.
Ex vivo systems to study chondrogenic differentiation and cartilage Integration.
J Funct Morphol Kinesiol. 2021;6(1):6Monaco G, El Haj AJ, Alini M, Stoddart MJ.
Quantification of 3D microstructural parameters of trabecular bone is affected by the analysis software.
Bone. 2021;142:115653 (epub 2020; Oct 12)Mys K, Varga P, Stockmans F, Gueorguiev B, Wyers CE, van den Bergh JPW, van Lenthe GH. In vivo test of a radiography-based navigation system for control of derotational osteotomies.
J Orthop Res. 2021;39(1):130-5 (epub 2020; Jun 21)Grünwald L, Schröter S, Windolf M, Gueorguiev B, Richards RG, Buschbaum J.
An impaired healing model of osteochondral defect in papain-induced arthritis.
J Orthop Translat. 2021;26:101-10 (epub 2020; Sep 22)Meng X, Grad S, Wen C, Lai Y, Alini M, Qin L, Wang X.
One strike loading organ culture model to investigate the post-traumatic disc degenerative condition.
J Orthop Translat. 2021;26:141-50 (epub 2020; Oct 20)Zhou Z, Cui S, Du J, Richards RG, Alini M, Grad S, Li Z. Serum biomarkers for Modic changes in patients with chronic low back pain.
Eur Spine J. 2021;30:1018-1027Karppinen J, Koivisto K, Ketola J, Haapea M, Paananen M, Herzig K-H, Alini M, Lotz J, Dudli S, Samartzis D, Risteli J, Majuri M-L, Alenius H, Kyllönen E, Järvinen J, Niinimäki J, Grad S.
Uncovering the secretome of mesenchymal stromal cells exposed to healthy, traumatic, and degenerative intervertebral discs: a proteomic analysis.
Stem Cell Res Ther. 2021;12(1):11Wangler S, Kamali A, Wapp C, Wuertz-Kozak K, Häckel S, Fortes C, Benneker LM, Haglund L, Richards RG, Alini M, Peroglio M, Grad S.
Antimicrobial resistance, the COVID-19 pandemic, and lessons for the orthopaedic community.
J Bone Joint Surg Am. 2021;103(1):4-9 (epub 2020; Dec 2)Metsemakers WJ, Zalavras C, Schwarz EM, Chen AF, Trampuz A, Moriarty TF. Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model.
Eur Cell Mater. 2021;41:40-51Sennett ML, Friedman JM, Ashley BS, Stoeckl BD, Patel JM, Alini M, Cucchiarini M, Eglin D, Madry H, Mata A, Semino C, Stoddart MJ, Johnstone B, Moutos FT, Estes BT, Guilak F, Mauck RL, Dodge GR.
From creative thinking to scientific principles in clinical practice.
Injury. 2020;51(1):32-6 (epub 2020; Sep 29)Lambert S, Mischler D, Windolf M, Regazzoni P, Dell'Oca AF, Gueorguiev B, Varga P.
The influence of biomechanical stability on bone healing and fracture-related infection: the legacy of Stephan Perren.
Injury. 2021;51(1):43-52 (epub 2020; Jun 26)Foster AL, Moriarty TF, Zalavras C, Morgenstern M, Jaiprakash A, Crawford R, Burch MA, Boot W, Tetsworth K, Miclau T, Ochsner P, Schuetz MA, Richards RG, Metsemakers WJ. Biomechanical analysis of peri-implant fractures in short versus long cephalomedullary implants following pertrochanteric fracture consolidation.
Injury. 2021;51(1):60-5 (epub 2020; Sep 18)Breceda A, Sands A, Zderic I, Schopper C, Schader J, Gehweiler D, Mischler D, Richards RG, Gueorguiev B.
Biomechanical evaluation of retrograde docking nailing to a total hip arthroplasty stem in a periprosthetic femur fracture model.
Injury. 2020;52:53-59 (epub 2020; Oct 19)Lenz M, Hofmann-Fliri L, Kasper LA, Varga P, Zderic I, Gehweiler D, Klos K, Hofmann GO, Stoffel K, Gueorguiev B.
MorpholoAgy of bony callus growth in healing of a sheep tibial osteotomy.
Injury. 2020:52:66-70 (epub 2020; Oct 19Wilson CJ, Epari DR, Ernst M, Arens D, Zeiter S, Windolf M. The relation between fracture activity and bone healing with special reference to the early healing phase - A preclinical study.
Injury. 2020;52:71-77 (epub 2020; Oct 10)Windolf M, Ernst M, Schwyn R, Arens D, Zeiter S.
A Tribute to Professor Stephan M Perren: ‘A pioneer and visionary man of the AO Foundation’.
Injury. 2021;52(1):1-2Giannoudis PV, Richards RG.
Publishing research that could be further developed and translated should continue to be a priority.
Injury. 2021;52(1):9-10Giannoudis PV, Richards RG. Biomechanical evaluation of the docking nail concept in periprosthetic fracture fixation around a stemmed total knee arthroplasty.
J Biomech. 2021;115:110109 (epub 2020; Nov 18)Lenz M, Acklin YP, Kasper LA, Mischler D, Varga P, Zderic I, Gehweiler D, Klos K, Gueorguiev B, Stoffel K.
Improving the accuracy of patient positioning for long-leg radiographs using a Taylor Spatial Frame mounted rotation rod.
Arch Orthop Trauma Surg. 2021;141(1):55-61 (epub 2020; May 6)Ahrend M-D, Finger F, Grünwald L, Keller G, Baumgartner H.
Antibiofilm efficacy of focused high-energy extracorporeal shockwaves and antibiotics in vitro.
Bone Joint Res. 2021;10(1):77-84Milstrey A, Rosslenbroich S, Everding J, Raschke MJ, Richards RG, Moriarty TF, Puetzler J. High-Resolution Cone-Beam Computed Tomography is a fast and promising technique to quantify bone microstructure and mechanics of the distal radius.
Calcif Tissue Int. 2021;108:314-323Mys K, Varga P, Stockmans F, Gueorguiev B, Neumann V, Vanovermeire O, Wyers CE, van den Bergh JPW, van Lenthe GH.
Optimization of hyaluronic acid-tyramine/silk-fibroin composite hydrogels for cartilage tissue engineering and delivery of anti-inflammatory and anabolic drugs.
Mater Sci Eng C Mater Biol Appl. 2021;120:111701 (epub 2020; Nov 5)Ziadlou R, Rotman S, Teuschl A, Salzer E, Barbero A, Martin I, Alini M, Eglin D, Grad S. Impact of low bone mass and antiresorptive therapy on antibiotic efficacy in a rat model of orthopedic device-related infection.
J Orthop Res. 2021;39(2):415-25 (epub 2020; Dec 15)Thompson K, Freitag L, Styger U, Camenisch K, Zeiter S, Arens D, Richards RG, Moriarty TF, Stadelmann VA.
Single-stage revision of MRSA orthopedic device-related infection in sheep with an antibiotic-loaded hydrogel.
J Orthop Res. 2021;39(2):438-48 (epub 2020; Dec 11)Foster AL, Boot W, Stenger V, D'Este M, Jaiprakash A, Eglin D, Zeiter S, Richards RG, Moriarty TF.
Overdrilling increases the risk of screw perforation in locked plating of complex proximal humeral fractures – a biomechanical cadaveric study.
J Biomech. 2021;117:110268Burkhard B, Schopper C, Ciric D, Mischler D, Gueorguiev B, Varga P. Leave it or fix it? How fixation of a small posterior malleolar fragment neutralizes rotational forces in trimalleolar fractures.
Arch Orthop Trauma Surg. 2021;epub Jan 28Evers J, Fischer M, Raschke M, Riesenbeck O, Milstrey A, Gehweiler D, Gueorguiev B, Ochman S. Experimental and numerical investigation of secondary screw perforation in the human proximal humerus.
J Mech Behav Biomed Mater. 2021;116:104344Panagiotopoulou VC, Ovesy M, Gueorguiev B, Richards RG, Zysset P, Varga P. Generic implant positioning technology based on hole projections in X-ray images.
J Med Device. 2021;15(2): 025002Windolf M, Richards RG. Cortical parameters predict bone strength at the tibial diaphysis, but are underestimated by HR-pQCT and muCT compared to histomorphometry.
J Anat. 2021;238(3):669-78 (epub 2020; Oct 20)Schmidutz F, Milz S, Schiuma D, Richards RG, Windolf M, Sprecher CM. Development and first biomechanical validation of a score to predict bone implant interface stability based on clinical qCT scans.
Scientific Reports. 2021;11(1):3273Wähnert D, Frank A, Ueberberg J, Heilmann LF, Sauzet O, Raschke MJ, Gehweiler D. Overweight patients benefit from high tibial osteotomy to the same extent as patients with normal weights but show inferior mid-term results.
Knee Surg Sports Traumatol Arthrosc. 2021;epub Feb 11Herbst M, Ahrend MD, Grünwald L, Fischer C, Schroter S, Ihle C. Local bone quality measure and construct failure prediction: a biomechanical study on distal femur fractures.
Arch Orthop Trauma Surg. 2021;epub Feb 15Gehweiler D, Styger U, Gueorguiev B, Colcuc C, Vordemvenne T, Wähnert D. A gentamicin and vancomycin loaded hyaluronic-acid hydrogel successfully eradicates chronic MRSA orthopedic infection in a sheep model.
Antimicrob Agents Chemother. 2021;65:01840-20Boot W, Schmid T, D'Este M, Guillaume O, Foster A, Decosterd L, Richards RG, Eglin D, Zeiter S, Moriarty TF.
The effect of hyaluronic acid on nucleus pulposus extracellular matrix production through hypoxia-inducible factor-1alpha transcriptional activation of CD44 under hypoxia.
Eur Cell Mater. 2021;41:142-52Zhang F, Liu X, Li B, Li Z, Grad S, Chen D, Gao M, Liu S. A proinflammatory, degenerative organ culture model to simulate early-stage intervertebral disc disease.
JoVE. 2021(168):e62100Saravi B, Lang G, Grad S, Alini M, Richards RG, Schmal H, Südkamp N, Li Z. Bone cement augmentation of femoral nail head elements increases their cut-out resistance in poor bone quality– A biomechanical study.
J Biomech. 2021;118:110301Sermon A, Zderic I, Khatchadourian R, Scherrer S, Knobe M, Stoffel K, Gueorguiev B. An anisotropic nanocomposite hydrogel guides aligned orientation and enhances tenogenesis of human tendon stem/progenitor cells.
Biomater Sci. 2021;9:1237-1245Xu Y, Yin H, Chu J, Eglin D, Serra T, Docheva D. Osteogenic differentiation of hBMSCs on porous photo-crosslinked poly(trimethylene carbonate) and nano-hydroxyapatite composites.
Eur Polym J. 2021;147:110335Geven MA, Lapomarda A, Guillaume O, Sprecher CM, Eglin D, Vozzi G, Grijpma DW. Effect of the Addition Frequency of 5-Azacytidine in Both Micro- and Macroscale Cultures.
Cell Mol Bioeng. 2021:14:121-130 (epub 2020; Oct 6)Kadekar S, Barbe L, Stoddart M, Varghese OP, Tenje M, Mestres G. Cortical bone thickness predicts the quantitative bone mineral density of the proximal humerus.
Arch Osteoporos. 2021;16(1):33Schmidutz F, Yan SG, Schopf C, Ihle C, Ahrend M-D, Sprecher CM. Artificial Intelligence and CT-based 3D statistical modeling to assess trans-sacral corridors and plan implant positioning.
J Orthop Res. 2021;39:2681-2692Kamer L, Noser H, Arand C, Handrich K, Rommens PM, Wagner D. Removal of cement-augmented screws in distal femoral fractures and the effect of retained screws and cement on total knee arthroplasty: a biomechanical investigation.
J Orthop Traumatol. 2021;22(1):5Wähnert D, Grüneweller N, Gueorguiev B, Vordemvenne T, Gehweiler D. Distance from the magnification device contributes to differences in lower leg length measured in patients with TSF correction.
Arch Orthop Trauma Surg. 2021;epub Mar 6Ahrend M-D, Rühle M, Springer F, Baumgartner H. Coaxial micro-extrusion of a calcium phosphate ink with aqueous solvents improves printing stability, structure fidelity and mechanical properties.
Acta Biomater. 2021;125:322-32Bagnol R, Sprecher C, Peroglio M, Chevalier J, Mahou R, Büchler P, Richards RG, Eglin D. Is bridge plating of comminuted humeral shaft fractures advantageous when using compression plates with three versus two screws per fragment? A biomechanical cadaveric study.
Biomed Res Int. 2021;2021:6649712
Gomes GS, Zderic I, Ahrend M-D, Kojima KE, Varga P, Belangero WD, Richards RG, Lambert SM, Gueorguiev B.
Effect of cyclic mechanical loading on immunoinflammatory microenvironment in biofabricating hydroxyapatite scaffold for bone regeneration.
Bioact Mater. 2021;6(10):3097-108Zhang P, Liu X, Guo P, Li X, He Z, Li Z, Stoddart MJ, Grad S, Tian W, Chen D, Zou X, Zhou Z, Liu S.
The tissue renin-angiotensin system and its role in the pathogenesis of major human diseases: Quo vadis?
Cells. 2021;10(3):650Saravi B, Li Z, Lang CN, Schmid B, Lang FK, Grad S, Alini M, Richards RG, Schmal H,
Südkamp N, Lang GM.
A hyaluronan and platelet-rich plasma hydrogel for mesenchymal stem cell delivery in the intervertebral disc: An organ culture study.
Int J Mol Sci. 2021;22(6):2963Russo F, Ambrosio L, Peroglio M, Guo W, Wangler S, Gewiess J, Grad S, Alini M, Papalia R, Vadalà G, Denaro V.
The role of noncoding RNAs in osteogenic differentiation of human periodontal ligament stem cells.
CMTRO. 2021;6:2472751221999229Ahmad P, Stoddart MJ, Della Bella E. Screw-in-screw fixation of fragility sacrum fractures provides high stability without loosening-biomechanical evaluation of a new concept.
J Orthop Res. 2021;39(4):761-70 (epub 2020; Oct 24)Zderic I, Wagner D, Schopper C, Lodde M, Richards RG, Gueorguiev B, Rommens P, Acklin YP.
3D computational anatomy of the scaphoid and its waist for use in fracture treatment.
J Orthop Surg Res. 2021;16(1):216Ahrend M-D, Teunis T, Noser H, Schmidutz F, Richards RG, Gueorguiev B, Kamer L. Radiographic parameter(s) influencing functional outcomes following angular stable plate fixation of proximal humeral fractures.
Int Orthop. 2021;45:1845-1852Ahrend M-D, Kühle L, Riedmann S, Bahrs SD, Bahrs C, Ziegler P. Humanized mice exhibit exacerbated abscess formation and osteolysis during the establishment of implant-associated Staphylococcus aureus osteomyelitis.
Front Immunol. 2021;12(809)Muthukrishnan G, Wallimann A, Rangel-Moreno J, de Mesy Bentley KL, Hildebrand M, Mys K, Kenney HM, Sumrall ET, Daiss JL, Zeiter S, Richards RG, Schwarz EM, Moriarty TF. Growth modulation of angular deformities with a novel constant force implant concept-preclinical results.
J Child Orthop. 2021;15:137-148Buschbaum J, Freitag L, Slongo TF, Zeiter S, Schütz M, Windolf M. Silk fiber-reinforced hyaluronic acid-based hydrogel for cartilage tissue engineering.
Int J Mol Sci. 2021;22(7):3635Weitkamp J-T, Wöltje M, Nußpickel B, Schmidt FN, Aibibu D, Bayer A, Eglin D, Armiento AR, Arnold P, Cherif C, Lucius R, Smeets R, Kurz B, Behrendt P.
Annular defects impair the mechanical stability of the intervertebral disc.
Global Spine J. 2021;epub Mar 30Chen J-X, Li Y-H, Wen J, Li Z, Yu B-S, Huang Y-C. In Memoriam : Robert Danis, an inspiration for Maurice Muller and origins of the AO Foundation.
Acta Orthop Belg. 2020;86(4):577-9Dauwe J, Nijs S, Gueorguiev B, Richards RG. Transcriptional profiling of intervertebral disc in a post-traumatic early degeneration organ culture model.
JOR Spine. 2021 Apr 8;4(3):e1146Cui S, Zhou Z, Chen X, Wei F, Richards RG, Alini M, Grad S, Li Z. The application of mesenchymal stromal cells and their homing capabilities to regenerate the intervertebral disc.
Int J Mol Sci. 2021;22(7):3519Croft AS, Illien-Jünger S, Grad S, Guerrero J, Wangler S, Gantenbein B. Standardized artificially created stable pertrochanteric femur fractures present more homogenous results compared to osteotomies for orthopaedic implant testing.
BMC Musculoskelet Disord. 2021;22(1):371Schader JF, Zderic I, Gehweiler D, Dauwe J, Mys K, Danker C, Acklin YP, Sommer C, Gueorguiev B, Stoffel K. Dexamethasone induces changes in osteogenic differentiation of human mesenchymal stromal cells via SOX9 and PPARG, but not RUNX2.
Int J Mol Sci. 2021;22(9):4785Della Bella E, Buetti-Dinh A, Licandro G, Ahmad P, Basoli V, Alini M, Stoddart MJ. Gut microbial-derived short-chain fatty acids and bone: a potential role in fracture healing.
Eur Cell Mater. 2021;41:454-70Wallimann A, Magrath W, Thompson K, Moriarty T, Richards RG, Akdis CA, O'Mahony L, Hernandez CJ.
An improved 2-aminoimidazole based anti-biofilm coating for orthopedic implants: activity, stability, and in vivo biocompatibility.
Front Microbiol. 2021;12(806)Coppola GA, Onsea J, Moriarty TF, Nehrbass D, Constant C, Zeiter S, Aktan MK, Braem A,Van der Eycken EV, Steenackers HP, Metsemakers W-J.
Asymmetry of the pelvic ring evaluated by CT-based 3D statistical modeling.
J Anat. 2021;238(5):1225-32 (epub 2020; Dec 31)Handrich K, Kamer L, Mayo K, Sawaguchi T, Noser H, Arand C, Wagner D, Rommens PM. Dental robotics: A disruptive technology.
Sensors. 2021;21(10):3308Ahmad P, Alam MK, Aldajani A, Alahmari A, Alanazi A, Stoddart M, Sghaireen MG. Noninvasive multimodal fluorescence and magnetic resonance imaging of whole-organ intervertebral discs.
Biomed Opt Express. 2021;12(6):3214-27Ren W, Cui S, Alini M, Grad S, Zhou Q, Li Z, Razansky D. Impact of renin-angiotensin system inhibitors and beta-blockers on dental implant stability.
Int J Implant Dent. 2021;7(1):31Saravi B, Vollmer A, Lang G, Adolphs N, Li Z, Giers V, Stoll P. Screw-blade fixation systems for implant anchorage in the femoral head: Horizontal blade orientation provides superior stability.
Injury. 2021;52:1861-1867Schopper C, Keck K, Zderic I, Migliorini F, Link B-C, Beeres FJP, Babst R, Nebelung S, Eschbach D, Knauf T, Ganse B, Schoeneberg C, Hildebrand F, Gueorguiev B, Knobe M.
Crosstalk between mesenchymal stromal cells and chondrocytes: The hidden therapeutic potential for cartilage regeneration.
Stem Cell Rev Rep. 2021;epub May 05Brose TZ, Kubosch EJ, Schmal H, Stoddart MJ, Armiento AR. Biomechanical comparison of five fixation techniques for unstable fragility fractures of the pelvic ring.
J Clin Med. 2021;10(11):2326Lodde MF, Katthagen JC, Schopper CO, Zderic I, Richards RG, Gueorguiev B, Raschke MJ,Hartensuer R.
Letter to the Editor regarding: "Does the helical blade lead to higher rates of fixation failure as compared to lag screw in the cephalomedullary nailing treatment of hip fractures? A systematic review and meta-analysis".
J Orthop Trauma. 2021;35:e355Link BC, van Veelen N, Knobe M, Gueorguiev B. Orthopedic screws insertion simulation with immediate feedback enhances surgical skill.
Clin Biomech. 2021;epub April 27:105367Keltz E, Fletcher J, Mora AJ, Yavnai N, Gueorguiev-Rüegg B, Keren Y. Fracture-related infection.
Bone Joint Res. 2021;10(6):351-3Baertl S, Metsemakers WJ, Morgenstern M, Alt V, Richards RG, Moriarty TF, Young K. [Health-related quality of life - an underestimated factor to evaluate the treatment success after open wedge HTO surgery: prospective 6-years follow-up]
Gesundheitsbezogene Lebensqualität - ein unterschätztes Kriterium zur Bewertung des Behandlungserfolgs und der Indikationsstellung bei HTO: prospektive 6-Jahres-Ergebnisse.
Z Orthop Unfall. 2021;159(3):288-97 (epub 2020; Feb 27)Herbst M, Kuwashima U, Ahrend MD, Gueorguiev BG, Schröter S, Ihle C. Smart implants in fracture care - only buzzword or real opportunity?
Injury. 2021;52(Suppl 2):S101-S5 (epub 2020; Sep 17)Ernst M, Richards RG, Windolf M. Tissue deformation controlling fracture healing.
J Biomech. 2021;125:110576Hente RW, Perren SM. Can optimizing the mechanical environment deliver a clinically significant reduction in fracture healing time?
Biomedicines. 2021;9(6):691Barcik J, Epari DR. Increased tibial tubercle-trochlear groove and patellar height indicate a higher risk of recurrent patellar dislocation following medial reefing.
Knee Surg Sports Traumatol Arthrosc. 2021;epub May 25Ahrend MD, Eisenmann T, Herbst M, Gueorguiev B, Keller G, Schmidutz F, Döbele S, Schröter S, Ihle C.
The non-steroidal anti-inflammatory drug carprofen negatively impacts new bone formation and antibiotic efficacy in a rat model of orthopaedic-device-related infection.
Eur Cell Mater. 2021;41:739-55Burch MA, Keshishian A, Wittmann C, Nehrbass D, Styger U, Muthukrishnan G, Arens D, Stadelmann VA, Richards RG, Moriarty TF, Thompson K.
Effect of expansion media and fibronectin coating on growth and chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells.
Sci Rep. 2021;11(1):1308Basoli V, Della Bella E, Kubosch EJ, Alini M, Stoddart MJ. Sodium hyaluronate supplemented culture medium combined with joint-simulating mechanical loading improves chondrogenic differentiation of human mesenchymal stem cells.
Eur Cell Mater. 2021;41:616-32Monaco G, El Haj AJ, Alini M, Stoddart MJ. A murine Staphylococcus aureus fracture-related infection model characterised by fracture non-union, staphylococcal abscess communities and myeloid-derived suppressor cells.
Eur Cell Mater. 2021;41:774-92Hofstee MI, Riool M, Gieling F, Stenger V, Constant C, Nehrbass D, Zeiter S, Richards RG, Zaat SA, Moriarty TF.
Fracture biomechanics influence local and systemic immune responses in a murine fracture-related infection model.
Biology Open. 2021;10(9):bio057315Sabaté Brescó M, Berset CM, Zeiter S, Stanic B, Thompson K, Ziegler M, Richards RG, O'Mahony L, Moriarty TF.
In vitro evaluation of a nanoparticle-based mRNA delivery system for cells in the joint.
Biomedicines. 2021;9(7):794Sturm L, Schwemberger B, Menzel U, Häckel S, Albers CE, Plank C, Rip J, Alini M,
Traweger A, Grad S, Basoli V.
Finite element analysis of fracture fixation.
Curr Osteoporos Rep. 2021;19:403-4016Lewis GS, Mischler D, Wee H, Reid JS, Varga P. Ligamentous Lisfranc injuries: analysis of CT findings under weightbearing.
Eur J Trauma Emerg Surg. 2021;47(4):1243-8 (epub 2020; Jan 16)Penev P, Qawasmi F, Mosheiff R, Knobe M, Lehnert M, Krause F, Raykov D, Richards G, Gueorguiev B, Klos K. Intracapsular femoral neck fractures — A surgical management algorithm.
Medicina.2021;57(8):791Fletcher JWA, Sommer C, Eckardt H, Knobe M, Gueorguiev B, Stoffel K. An experimentally informed statistical elasto-plastic mineralised collagen fibre model at the micrometre and nanometre lengthscale.
Sci Rep. 2021;11(1):15539Groetsch A, Zysset PK, Varga P, Pacureanu A, Peyrin F, Wolfram U. One size may not fit all: patient-specific computational optimization of locking plates for improved proximal humerus fracture fixation.
J Shoulder Elbow Surg. 2021;epub Jul 20Schader JF, Mischler D, Dauwe J, Richards RG, Gueorguiev B, Varga P. Non-union bone fractures.
Nat Rev Dis Primers. 2021;7(1):57Wildemann B, Ignatius A, Leung F, Taitsman LA, Smith RM, Pesantez R, Stoddart MJ, Richards RG, Jupiter JB.
A single-cell transcriptome of mesenchymal stromal cells to fabricate bioactive hydroxyapatite materials for bone regeneration.
Bioact Mater. 2021;9:281-298Guo P, Liu X, Zhang P, He Z, Li Z, Alini M, Richards RG, Grad S, Stoddart MJ, Zhou G, Zou X, Chan D, Tian W, Chen D, Gao M, Zhou Z, Liu S.
Short-term bone healing response to mechanical stimulation—A case series conducted on sheep.
Biomedicines. 2021;9(8):988Barcik J, Ernst M, Balligand M, Dlaska CE, Drenchev L, Zeiter S, Epari DR, Windolf M. Reduced pre-operative skin oxygen saturation predicts revision after open reduction and internal fixation in calcaneal fractures.
Int Orthop. 2021;45:2355-2363Knobe M, Iselin LD, van de Wall BJM, Lichte P, Hildebrand F, Beeres FJP, Link BC,
Gueorguiev B, Nebelung S, Ganse B, Migliorini F, Klos K, Babst R, Haefeli PC.
Modeling of the human bone environment: Mechanical stimuli guide mesenchymal stem cell–extracellular matrix interactions.
Materials. 2021;14(16):4431Pereira AR, Lipphaus A, Ergin M, Salehi S, Gehweiler D, Rudert M, Hansmann J, Herrmann M. Helical plating - a novel technique to increase stiffness in defect fractures.
Eur Cell Mater. 2021;42:110-21Lenz M, Varga P, Mischler D, Gueorguiev B, Klos K, Fernandez dell'Oca A, Regazzoni P,
Richards RG, Perren SM.
The effect of the mobile subtalar joint on calcaneal and supramalleolar osteotomies.
Foot Ankle Int. 2021;42:1606-1612Krause F, Zderic I, Gueorguiev B, Vellasamy A, Schmid T. Anatomical evaluation of the transpubic screw corridor based on a 3D statistical model of the pelvic ring.
Sci Rep. 2021;11(1):16677Arand C, Wagner D, Richards RG, Noser H, Kamer L, Gehweiler D, Hopf J, Rommens PM. Material properties of human vertebral trabecular bone under compression can be predicted based on quantitative computed tomography.
BMC Musculoskelet Disord. 2021;22(1):709Gehweiler D, Schultz M, Schulze M, Riesenbeck O, Wähnert D, Raschke MJ. Impact of bone cement augmentation on the fixation strength of TFNA blades and screws.
Medicina. 2021;57(9):899Sermon A, Hofmann-Fliri L, Zderic I, Agarwal Y, Scherrer S, Weber A, Altmann M, Knobe M, Windolf M, Gueorguiev B.
3D geometry of femoral reaming for bone graft harvesting.
Sci Rep. 2021;11(1):17153Gehweiler D, Schmitz N, Gueorguiev B, Zderic I, Grünwald L, Richards RG, Wähnert D, Raschke MJ.
Is a block of the femoral and sciatic nerves an alternative to epidural analgesia in sheep undergoing orthopaedic hind limb surgery? A prospective, randomized, double blinded experimental trial.
Animals. 2021;11(9):2567Stenger V, Zeiter S, Buchholz T, Arens D, Spadavecchia C, Schüpbach-Regula G, Rohrbach H. Mechanical evaluation of two hybrid locking plate designs for canine pancarpal arthrodesis.
Biomed Res Int. 2021;2021:2526879Zderic I, Varga P, Styger U, Drenchev L, Gueorguiev B, Asimus E, Saunders WB, Kowaleski M, Boudrieau RJ, Dejardin LM.
Mesenchymal stromal cell differentiation for generating cartilage and bone-like tissues in vitro.
Cells. 2021;10(8):2165Monaco G, Ladner YD, El Haj AJ, Forsyth NR, Alini M, Stoddart MJ. Titanium wear particles exacerbate S. epidermidis-induced implant-related osteolysis and decrease efficacy of antibiotic therapy.
Microorganisms. 2021;9(9):1945Siverino C, Freitag L, Arens D, Styger U, Richards RG, Moriarty TF, Stadelmann VA, Thompson K.
Screw placement in two different implants for proximal humeral fractures regarding regional differences in bone mineral density: An anatomical study.
Injury. 2021;52(Suppl 5):S17-S21 (epub 2020; Oct 10)Holweg P, Dauwe J, Grechenig P, Holter M, Staresinic M, Feigl G, Bakota B. On measuring implant fixation stability in ACL reconstruction.
Sensors. 2021;21(19):6632Benca E, Zderic I, Caspar J, van Knegsel K, Hirtler L, Gueorguiev B, Widhalm H, Windhager R, Varga P. An enzybiotic regimen for the treatment of methicillin-resistant staphylococcus aureus orthopaedic device-related infection.
Antibiotics. 2021;10(10):1186Sumrall ET, Hofstee MI, Arens D, Röhrig C, Baertl S, Gehweiler D, Schmelcher M, Loessner MJ, Zeiter S, Richards RG, Moriarty TF.
In vitro model to investigate communication between dorsal root ganglion and spinal cord glia.
Int J Mol Sci. 2021;22(18):9725Ma J, Patil V, Pandit A, Quinlan LR, Finn DP, Grad S, Alini M, Peroglio M. Raman spectroscopy in skeletal tissue disorders and tissue engineering: present and prospective.
Tissue Eng Part B Rev. 2021;epub Sep 28Fosca M, Basoli V, Della Bella E, Russo F, Vadala G, Alini M, Rau JV, Verrier S. Evaluation of the influence of platelet-rich plasma (PRP), platelet lysate (PL) and mechanical loading on chondrogenesis in vitro.
Sci Rep. 2021;11(1):20188Pötter N, Westbrock F, Grad S, Alini M, Stoddart MJ, Schmal H, Kubosch D, Salzmann G, Kubosch EJ. The function of CD146 in human annulus fibrosus cells and mechanism of the regulation by TGF-beta.
J Orthop Res. 2021;epub Oct 18Du J, Guo W, Hackel S, Hoppe S, Garcia JP, Alini M, Tryfonidou MA, Creemers LB, Grad S, Li Z.
Is anterior plating superior to the bilateral use of retrograde transpubic screws for treatment of straddle pelvic ring fractures? A biomechanical investigation.
J Clin Med. 2021;10(21):5049Lodde MF, Katthagen JC, Schopper CO, Zderic I, Richards RG, Gueorguiev B, Raschke MJ, Hartensuer R. Influence of axial limb rotation on radiographic lower limb alignment: a systematic review.
Arch Orthop Trauma Surg. 2021;epub Oct 1Ahrend MD, Baumgartner H, Ihle C, Histing T, Schröter S, Finger F. Visible light-induced 3D bioprinting technologies and corresponding bioink materials for tissue engineering: A review.
Engineering, 2021; 7: 966-978 (epub 2020; Sep 20)Zheng Z, Eglin D, Alini M, Richards RG, Qin L, Lai Y. In vitro 3D staphylococcus aureus abscess communities induce bone marrow cells to expand into myeloid-derived suppressor cells.
Pathogens. 2021;10(11):1446Hofstee MI, Heider A, Häckel S, Constant C, Riool M, Richards RG, Moriarty TF, Zaat SAJ. Hyaluronic acid-based interpenetrating network hydrogel as a cell carrier for nucleus pulposus repair.
Carbohydr Polym. 2021;epub Oct 29Guo W, Douma L, Hu MH, Eglin D, Alini M, Secerovic A, Grad S, Peng X, Zou X, D'Este M, Peroglio M.
Incorporation of hydroxyapatite into collagen scaffolds enhances the therapeutic efficacy of rhBMP-2 in a weight-bearing femoral defect model.
Mater Today Commun. 2021;29:102933Lackington WA, Gehweiler D, Zderic I, Nehrbass D, Zeiter S, González-Vázquez A, O’Brien FJ, Stoddart MJ, Thompson K.
Quality control methods in musculoskeletal tissue engineering: from imaging to biosensors.
Bone Res. 2021;9(1):46Zuncheddu D, Della Bella E, Schwab A, Petta D, Rocchitta G, Generelli S, Kurth F, Parrilli A, Verrier S, Rau JV, Fosca M, Maioli M, Serra PA, Alini M, Redl H, Grad S, Basoli V.
Adaptive local thresholding can enhance the accuracy of HR-pQCT-based trabecular bone morphology assessment.
Bone. 2021;epub Oct 9:116225Mys K, Stockmans F, Gueorguiev B, Wyers CE, van den Bergh JPW, van Lenthe GH, Varga P. Biomechanical analysis of recently released cephalomedullary nails for trochanteric femoral fracture fixation in a human cadaveric model.
Arch Orthop Trauma Surg. 2021;epub Nov 8Pastor T, Zderic I, Gehweiler D, Gardner MJ, Stoffel K, Richards RG, Knobe M, Gueorguiev B. RIA versus iliac crest bone graft harvesting: A meta-analysis and systematic review.
Injury.
2021;epub Oct 15van de Wall BJM, Beeres FJP, Rompen IF, Link BC, Babst R, Schoeneberg C, Michelitsch C, Nebelung S, Pape HC, Gueorguiev B, Knobe M.
Trochanteric femur fractures: application of skeletal traction during surgery does not alter soft-tissue microcirculation.
Medicina (Kaunas). 2021;57(9):884van Knegsel KP, Ganse B, Haefeli PC, Migliorini F, Scaglioni MF, van de Wall BJM, Kim BS, Link BC, Beeres FJP, Nebelung S, Schoeneberg C, Hildebrand F, Gueorguiev B, Knobe M. Angular stable locking in a novel intramedullary nail improves construct stability in a distal tibia fracture model.
Injury. 2021;epub Nov 6Zderic I, Gueorguiev B, Blauth M, Weber A, Koch R, Dauwe J, Schader JF, Stoffel K, Finkemeier C, Hessmann M.
Research practices and needs among spine surgeons worldwide.
Global Spine J. 2021;epub Dec 6Germscheid N, Cheung JPY, Neva MH, Oner FC, Kwon BK, Valacco M, Awwad W,
Sciubba DM, Lewis SJ, Rhines LD, Yoon ST, Alini M, Grad S, Fisher CG, Samartzis D.Does cement augmentation of the sacroiliac screw lead to superior biomechanical results for fixation of the posterior pelvic ring? A biomechanical study.
Medicina. 2021;57(12):1368Lodde MF, Katthagen JC, Schopper CO, Zderic I, Richards RG, Gueorguiev B, Raschke MJ, Hartensuer R.
Bacteriophage therapy for the prevention and treatment of fracture-related infection caused by staphylococcus aureus: a preclinical study.
Microbiol Spectr. 2021;9:e0173621Onsea J, Post V, Buchholz T, Schwegler H, Zeiter S, Wagemans J, Pirnay JP, Merabishvili M, D'Este M, Rotman SG, Trampuz A, Verhofstad MHJ, Obremskey WT, Lavigne R, Richards RG, Moriarty TF, Metsemakers WJ.
Butyrate inhibits osteoclast activity in vitro and regulates systemic inflammation and bone healing in a murine osteotomy model compared to antibiotic-treated mice.
Mediators Inflamm. 2021;2021:8817421Wallimann A, Magrath W, Pugliese B, Stocker N, Westermann P, Heider A, Gehweiler D, Zeiter S, Claesson MJ, Richards RG, Akdis CA, Hernandez CJ, O’Mahony L, Thompson K, Moriarty TF.
Establishment of an ex vivo inflammatory osteoarthritis model with human osteochondral explants.
Front Bioeng Biotechnol. 2021;9:787020Li K, Zhang P, Zhu Y, Alini M, Grad S, Li Z. Cortical bone thickness of the distal radius predicts the local bone mineral density.
Bone Joint Res. 2021;10(12):820-9Schmidutz F, Schopf C, Yan SG, Ahrend MD, Ihle C, Sprecher C. Screw tightness and stripping rates vary between biomechanical researchers and practicing orthopaedic surgeons.
J Orthop Surg Res. 2021;16(1):642Fletcher JWA, Neumann V, Wenzel L, Gueorguiev B, Richards RG, Gill HS, Whitehouse MR, Preatoni E.
Is intrathoracic rib plate fixation advantageous over extrathoracic plating? A biomechanical cadaver study.
J Trauma Acute Care Surg. 2021;epub Oct 22Mischler D, Schopper C, Gasparri M, Schulz-Drost S, Brace M, Gueorguiev B. Bone infection: a clinical priority for clinicians, scientists and educators.
Eur Cell Mater. 2021;42:312-33Moriarty TF, Muthukrishnan G, Daiss JL, Xie C, Nishitani K, Morita Y, Awad H, de Mesy Bentley KL, Masters E, Bui T, Yan M, Owen J, Mooney B, Gill S, Puetzler J, Wenke JC, Morgenstern M, Metsemakers WJ, Noll C, Joeris A, Richards RG, Schwarz EM, Kates SL.
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Theses and Dissertations
2020
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Abstracts published in journals
Device-induced Growth Plate Lesions. Classic Examples in Toxicologic Pathology XXVII, 2020 (oral)
Nehrbass D, Cheney D, Gehweiler D, Hearn J, Hildebrand M, Mukhopadhaya J, Narayanan U, Schmittenbecher P, Sepulveda-Oviedo M, Slongo T, Zeiter S, Gueorguiev B, Dwyer JSM.
Is the risk of secondary peri-implant fracture after trochanteric fracture consolidation similar when using short or long TFNA?
Swiss Med Wkly. 2020;150(Suppl 244):38 (swiss orthop e-congress / oral)Breceda A, Zderic I, Schopper C, Schader J, Gehweiler D, Richards RG, Gueorguiev B, Sands A.
Screw-blade fixation systems in proximal femur fractures: a biomechanical evaluation.
Swiss Med Wkly. 2020;150(Suppl 244):23 (swiss orthop e-congress / oral)Schopper C, Keck K, Beeres F, Link B-C, Babst R, Nebelung S, Zderic I, Gueorguiev B, Knobe M.
A new concept for screw-in-screw fixation of fragility sacrum fractures – biomechanical comparison versus transsacral and SI screw fixations.
Swiss Med Wkly. 2020;150(Suppl 244):39-40 (swiss orthop e-congress / oral)Zderic I, Schopper C, Lodde M, Wagner D, Richards RG, Gueorguiev B, Rommens P, Acklin Y.
Correlation between pelvic incidence and acetabular orientation in anteversion and inclination—an analysis based on a 3D statistical model of the pelvic ring.
Eur J Trauma Emerg Surg. 2020;46(S1):S226 (ECTES congress called off / abstract published)Arand C, Wagner D, Kamer L, Noser H, Richards RG, Rommens PM.
Three-dimensional segmented CT images help orthopedic surgeons and residents to correctly classify proximal humeral fractures.
Z Orthop Unfall. 2020;158(S01):S66-S67 (DKOU congress called off / abstract published, oral)Dauwe J, Mys K, Putzeys G, Schader J, Richards RG, Gueorguiev B, Varga P, Nijs S.
Does coronoid process replacement with individually designed 3D printed prosthesis provide superior stability over grafted reconstruction and screw fixation? A biomechanical study.
Z Orthop Unfall. 2020;158(S01):S122-S123 (DKOU congress called off / abstract published, oral)Gueorguiev B, Pukalski Y, Barcik J, Zderic I, Yanev P, Rashkov M, Baltov A, Enchev D.
3D Drucken von Kollagenfibrillen mit Kontrolle über deren Orientierung in einer Hyaluronsäure Matrix als biomimetisches Knorpelimplantat.
Z Orthop Unfall. 2020;158(S01):S220-S221 (DKOU congress called off / abstract published, oral)Schwab A, Alini M, Eglin D, D’Este M.
Korrelation zwischen Pelvic Incidence und räumlicher Orientierung des Acetabulums - eine Analyse basierend auf einem 3D statistischen Modell des Beckenrings.
Z Orthop Unfall. 2020;158(S01):S98-S99 (DKOU congress called off / abstract published, oral)Arand C, Wagner D, Kamer L, Noser H, Richards RG, Rommens PM.
Computertomographische Stabilitäts-Untersuchung im trimalleolären Sprunggelenksfrakturmodell unter axialer Last.
Z Orthop Unfall. 2020;158(S01):S125-S126 (DKOU congress called off / abstract published, oral)Evers J, Fischer M, Milstrey A, Riesenbeck O, Gehweiler D, Gueorguiev-Rüegg B, Raschke MJ, Ochman S. Innovative Fixierungssysteme bei proximalen Femurfrakturen: Sind Klingen-Schrauben-Kombinationen die Zukunft?
Z Orthop Unfall. 2020;158(S01):S109 (DKOU congress called off / abstract published, oral)Keck K, Schopper C, Beeres F, Link BC, Babst R, Nebelung S, Gueorguiev B, Knobe M.
Biomechanische Untersuchung posteriorer Fixierungsmethoden von C1.3 Beckenringfrakturen.
Z Orthop Unfall. 2020;158(S01):S225 (DKOU congress called off / abstract published, oral)Lodde MF, Katthagen JC, Zderic I, Schopper C, Gueorguiev-Rüegg B, Riesenbeck O, Raschke MJ, Hartensuer R.
Biomechanischer Vergleich gängiger Techniken zur Stabilisierung des Beckenrings bei Insuffizienzfrakturen.
Z Orthop Unfall. 2020;158(S01):S221-S222 (DKOU congress called off / abstract published, oral)Lodde MF, Katthagen JC, Zderic I, Schopper C, Gueorguiev-Rüegg B, Riesenbeck O, Raschke MJ, Hartensuer R.
Eine Methode zur Messung der intradiskalen Druckverteilung und des Footprints intervertebraler Implantate - Möglichkeiten und Limitationen.
Z Orthop Unfall. 2020;158(S01):S190-S191 (DKOU congress called off / abstract published, oral)Riesenbeck O, Schulze M, Gehweiler D, Raschke MJ, Hartensuer R.
Die protektive Wirkung von Losartan auf humane Nucleus Pulposus Zellen.
Z Orthop Unfall. 2020;158(S01):S89-S90 (DKOU congress called off / abstract published, oral)Wystrach L, Pfannkuche J, Li Z, Grad S, Kubosch DC, Schmal H, Alini M, Lang G.
Einfluss der anisotropen Faserausrichtung und des Kollagen Typs und auf das chondrogene Differenzierungsverhalten.
Z Orthop Unfall. 2020;158(S01):S20 (DKOU congress called off / abstract published, poster)Schwab A, Staubli F, Alini M, Eglin D, D’Este M.
Biomechanische Untersuchung der transpubischen Schraubenosteosynthese und der anterioren Plattenosteosynthese bei Schmetterlingsfrakturen des Beckenrings.
Z Orthop Unfall. 2020;158(S01):S229-S230 (DKOU congress called off / abstract published, poster)Lodde MF, Katthagen JC, Zderic I, Schopper C, Gueorguiev-Rüegg B, Riesenbeck O, Raschke MJ, Hartensuer R.
Ankle joint pressure in supination-external rotation injuries: A dynamic biomechanic cadaveric study.
Foot Ankle Orthop. 2020;5(4) (AOFAS virtual / poster)Krause F, Zderic I, Seidel A, Gueorguiev B, Attinger MC, Foesel A.
Cyclic perforation risk is increased by overdrilling in locked plating of complex proximal humerus fractures.
Bone Joint J. 2020;102-B(Suppl. 11 / Orthop Proc): 75 (EORS virtual, oral)Burkhard B, Schopper C, Ciric D, Mischler D, Gueorguiev B, Varga P.
Angular stable locking in a novel intramedullary nail improves construct stability in a distal tibia fracture model.
Bone Joint J. 2020;102-B(Suppl. 11 / Orthop Proc):27 (EORS virtual, oral)Gueorguiev B, Zderic I, Blauth M, Weber A, Koch R, Dauwe J, Schader J, Stoffel K, Finkemeier C, Hessmann M.
Screw fixation of Sanders type II-B calcaneal fractures: Biomechanical analysis of different screw configurations.
Bone Joint J. 2020;102-B(Suppl. 11 / Orthop Proc):77 (EORS virtual, oral)Ivanov S, Stefanov A, Zderic I, Gehweiler D, Richards RG, Raykov D, Gueorguiev B.
Can unstable proximal tibial fractures with soft tissue injury be successfully treated with external locked plating?
Bone Joint J. 2020;102-B(Suppl. 11 / Orthop Proc):49 (EORS virtual, oral)Makelov B, Gueorguiev B, Apivatthakakul T.
Micro finite element simulations accurately predict perforation of single screws in the proximal humerus.
Bone Joint J. 2020;102-B(Supp. 11 / Orthop Proc):65 (EORS virtual, oral)Panagiotopoulou V, Ovesy M, Gueorguiev B, Richards RG, Zysset P, Varga P.
Biomechanical comparison of three coronoid treatment modalities: Prosthesis vs autograft vs fixation.
Bone Joint J. 2020;102-B(Suppl. 11 / Orthop Proc):71 (EORS virtual, oral)Pukalski Y, Barcik J, Zderic I, Yanev P, Baltov A, Rashkov M, Richards RG, Gueorguiev B, Enchev D.
Variable-angle locked plating versus interlocked nailing for intraarticular calcaneal fractures – a biomechanical study.
Bone Joint J. 2020;102-B(Suppl. 11 / Orthop Proc):85 (EORS virtual, oral)Stefanov A, Ivanov S, Zderic I, Baltov A, Rashkov M, Gehweiler D, Richards RG, Gueorguiev B, Enchev D.
Is the risk of secondary peri-implant fracture after trochanteric consolidation similar when using short or long TFNA?
Bone Joint J. 2020;102-B(Suppl. 11 / Orthop Proc):82 (EORS virtual, oral)Zderic I, Breceda A, Schopper C, Schader J, Gehweiler D, Richards RG, Gueorguiev B, Sands A.
Screw-in-screw fixation of fragility sacrum fractures provides high stability without loosening: A biomechanical study.
Bone Joint J. 2020;102-B(Suppl. 11 / Orthop Proc):81 (EORS virtual, oral)Zderic I, Schopper C, Wagner D, Gueorguiev B, Rommens P, Acklin Y.
Human mesenchymal stem cells encapsulated in hyaluronic acid and platelet-rich plasma modulate matrix synthesis ex vivo.
Bone Joint J. 2020;102-B(Suppl. 11 / Orthop Proc):95 (EORS virtual, poster)Russo F, Ambrosio L, Peroglio M, Wangler S, Guo W, Grad S, Alini M, Vadalà G, Papalia R, Denaro V.
Local adaptation of bone micro-structure and canal network to tendon insertion investigated by image-based micro-FE simulations.
Bone Reports. 2020;13(Suppl):100393 (ECTS digital / poster)Tits A, Varga P, Kaux J-F, Plougonven E, Fernandez J, Drion P, Van Lenthe GH, Ruffoni D.
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Books and book chapters
Racing for the Surface. Antimicrobial and Interface Tissue Engineering.
Cham: Springer Nature Switzerland 2020Li B, Moriarty TF, Webster T, Xing M (editors).
Racing for the Surface. Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies.
Cham: Springer Nature Switzerland 2020.Li B, Moriarty TF, Webster T, Xing M (editors).
Fracture Healing and Progress Towards Successful Repair.
In: Li B, Moriarty TF, Webster T, Xing M (editors). Racing for the Surface. Antimicrobial and Interface Tissue Engineering.
Cham: Springer; 2020. p. 225-43.Lackington WA, Thompson K.
Complications in Orthopedic Trauma Surgery: Fracture-Related Infection.
In: Li B, Moriarty TF, Webster T, Xing M (editors). Racing for the Surface. Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies.
Cham: Springer; 2020. p. 33-56.Burch MA, Moriarty TF, Kuehl R, Foster A, Morgenstern M.
Periprosthetic Joint Infection.
In: Li B, Moriarty TF, Webster T, Xing M (editors). Racing for the Surface. Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies.
Cham: Springer; 2020. p. 57-74.Keshishian A, Foster A, Matziolis G, Moriarty TF, Eijer H.
Patterned nanocomposites generated via electric/magnetic fields for hierarchical tissue regeneration.
In: Guarino V, Iafisco M, Spriano S (editors).
Nanostructured Biomaterials for Regenerative Medicine.
Woodhead Publishing Series in Biomaterials: Woodhead Publishing; 2020. p. 203-20Serra T, Tognato R, Augurio A.
Growth factors for craniomaxillofacial applications.
In: Ehrenfeld M, Futran ND, Manson PN, Prein J (editors).
Advanced Craniomaxillofacial Surgery. Tumor, Corrective Bone Surgery and Trauma.
Davos: AO Foundation / Thieme; 2020. p. 68-79Stoddart M, Richards RG.
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Conference presentations
Acoustic waves cell patterning for spatially orchestrated vasculature system in tissue engineering.
2020 SSB+RM YSS (oral)Di Marzio N, Richards RG, Alini M, Eglin D, Serra T.
Calcium Polyphosphate Nanoparticles Act as an Effective Inorganic Phosphate Source during the in vitro Osteogenic Differentiation of Human Mesenchymal Stem Cells.
2020 SSB+RM YSS (oral)Hatt LP, Thompson K, Müller WEG, Stoddart MJ, Armiento AR.
Local bacteriophage delivery by a thermo-responsive hydrogel system for treatment of medical infections – an in vitro assessment.
2020 SSB+RM YSS (poster / rfo)Rotman SG, Grijpma DW, Post V, Eglin D, Moriarty TF.
Development of an ECM derived tough hydrogel for cartilage tissue engineering.
2020 SSB+RM YSS (poster)Yamamoto T.
Regulation of Inflammatory Response in Human Osteoarthritic Chondrocytes by Novel Herbal Small Molecules.
2020 SSB+RM YSS (poster)Ziadlou R, Barbero A, Stoddart MJ, Wirth M, Li Z, Martin I, Wang X, Qin L, Alini M, Grad S.
The influence of microbial-derived metabolites on bone health.
2020 EAACI IWS (poster)Wallimann A, Thompson K, Moriarty TF, Akdis C, O'Mahony L.
Dexamethasone regulates circular RNA expression in early osteogenesis and chondrogenesis of human bone marrow mesenchymal stromal cells.
2020 ORS (oral)Della Bella E, Menzel U, Stoddart MJ.
Polyphosphate Nanoparticles Act as an Effective Inorganic Phosphate Source during Osteogenic Differentiation of BM-MSCs.
2020 ORS (poster)Armiento AR, Hatt LP, Müller WEG, Thompson K, Stoddart MJ.
Predicting and promoting human MSC chondrogenesis by way of TGFβ receptor profiles: Towards personalized medicine.
2020 ORS (poster)Basoli V, Rothweiler R, Johnstone B, Alini M, Stoddart MJ.
Local delivery of IL-1Ra as a strategy to enhance long bone healing.
2020 ORS (poster)Lackington W, Hildebrand M, Alini M, Zeiter S, Thompson K.
Controlled factorial design of experiment to optimize mechano-induced chondrogenesis of human MSCs – A feasibility study.
2020 ORS (poster)Ladner Y, Armiento AR, Snedeker JG, Stoddart MJ.
Angiotensin II receptor antagonist inhibits TNFα induced degeneration process in human nucleus pulposus cells.
2020 ORS (poster)Li Z, Pfannkuche J, Kubosch D, Südkamp N, Alini M, Grad S, Lang G.
Morphological and biomechanical effects of annulus fibrosus injury and repair in an ovine cervical model.
2020 ORS (poster)Long RG, Ferguson SJ, Benneker L, Sakai D, Li Z, Pandit A, Grijpma DW, Eglin D, Zeiter S,
Schmid T, Eberli U, Nehrbass D, Iatridis JC, Alini M, Grad S.Superior stability of coronoid process replacement achieved via individually designed 3D printed prosthesis with curved cemented intramedullary stem.
2020 ORS (poster)Pukalski Y, Barcik J, Zderic I, Yanev P, Baltov A, Rashkov M, Richards RG, Gueorguiev B, Enchev D.
Locally delivered mesenchymal stem cell homing enables intervertebral disc repair: A proof-of-concept study.
2020 ORS (poster)Schol J, Sakai D, Takayuki W, Peroglio M, Li Z, Wangler S, Zeiter S, Grad S, Alini M.
Annulus fibrosus tissue engineering using 3D printed poly(ε-caprolactone) scaffolds with oriented ply structure.
2020 ORS (poster)Vernengo A, Li Z, Mys K, Varga P, Grad S, Alini M, Eglin D.
TightRight: augmenting screwdrivers to reduce bone stripping rates and optimise tightness when inserting non-locking screws.
2020 ORS (poster / ICORS best posters)Fletcher JWA, Neumann V, Silva J, Mys K, Panagiotopoulou VC, Verschueren A, Gueorguiev B,
Richards RG, Whitehouse M, Preatoni E, Gill H.Eine periprothetische Infektion mit Actinomyces radingae könnte zur Identifikation einer missachteten Quelle intraoperativer Kontamination führen.
2020 Endoprothetik (poster)Kuttner H, Pfister S, Moriarty TF, Aepli M, Meier C, Kalberer F, Wahl P.
Improving stability of proximal humerus fracture locked plating by means of patient-specific computational optimization.
2020 AGA virtual (oral)Schader JF, Mischler D, Dauwe J, Gueorguiev B, Varga P.
Human mesenchymal stem cells encapsulated in hyaluronic acid and platelet-rich plasma modulate matrix synthesis ex vivo.
2020 EORS virtual (poster)Russo F, Ambrosio L, Peroglio M, Wangler S, Guo W, Grad S, Alini M, Vadalà G, Papalia R, Denaro V.
Standardized fractures – introducing a novel approach to orthopedic implant testing.
2020 EORS virtual (poster)Schader JF, Zderic I, Gehweiler D, Dauwe J, Mys K, Danker C, Acklin Y, Gueorguiev B, Stoffel K.
3D printing of a calcium phosphate paste for the production of patient specific bone substitutes.
2020 GR forscht virtual (oral)Bagnol R, Sprecher CM, Peroglio M, Richards RG, Eglin D.
High impact loading organ culture model to investigate the post-traumatic disc degenerative condition.
2020 GR forscht virtual (oral)Cui S, Zhou Z, Alini M, Grad S, Li Z.
3-dimensional in vitro Staphylococcus aureus abscess communities display antibiotic tolerance and protection from neutrophil clearance.
2020 GR forscht virtual (oral)Hofstee M, Riool M, Terjajevs I, Thompson K, Stoddart M, Zaat SA, Moriarty TF.
Local non-viral gene delivery to immunomodulate and enhance fracture healing.
2020 GR forscht virtual (oral)Lackington W, Gomez M, Vazquez A, O'Brien FJ, Thompson K.
Full factorial design of experiment elucidates interaction of mechanical parameters driving in vitro cartilage formation in a bioreactor.
2020 GR forscht virtual (oral)Ladner Y, Armiento AR, Snedeker JG, Stoddart MJ.
Towards a reproducible intervertebral disc model – a bioprintable nucleus pulposus-like material.
2020 GR forscht virtual (oral)Miklosic G, Eglin D, D'Este M.
Bone targeted antibiotic delivery with functionalized poly (ϵ-caprolactone) microparticles.
2020 GR forscht virtual (oral)Rotman S, Grijpma D, Richards RG, Moriarty TF, Eglin D, Guillaume O.
Biomechanical comparison of standardized stable pertrochanteric fractures versus osteotomies for orthopaedic implant testing.
2020 GR forscht virtual (oral)Schader JF, Zderic I, Dauwe J, Mys K, Gehweiler D, Acklin Y, Gueorguiev B, Stoffel K.
Unloading of intervertebral disc to improve low back pain management: from organ model to clinics.
2020 GR forscht virtual (oral)Soubrier A, Grad S, Alini M, I. J, Peroglio M.
The influence of short-chain fatty acids on bone health.
2020 GR forscht virtual (oral)Wallimann A, Thompson K, Moriarty TF, Akdis C, O'Mahony L.
Real time quality monitoring of engineered tissue for regenerative medicine.
2020 GR forscht virtual (oral)Zuncheddu D, Generelli S, Kurth F, Serra PA, Rocchitta G, Grad S, Basoli V.
Continuous monitoring of bone healing by measurement of fracture callus stiffness.
2020 GR forscht virtual (poster)Barcik J, Ernst M, Balligand M, Dlaska CE, Drenchev L, Todorov S, Gueorguiev B, Skulev H, Zeiter S, Epari D, Windolf M.
The missing link: From mechanical intervertebral disc overloading to low back pain.
2020 GR forscht virtual (poster)Gewiess J, Ma J, Richards RG, Grad S, Alini M, Peroglio M.
Papain-induced ex vivo model for intervertebral disc degeneration and the influence of daily physiological loading.
2020 GR forscht virtual (poster)Kluser N, Vernengo A, Jansen JU, Neidlinger-Wilke C, Wilke HJ, Li Z, Grad S.
Patient-specific aiming device increases precision of guide wire placement in arthritic glenoids – an experimental study.
2020 GR forscht virtual (poster)Schader JF, Helfen T, Braunstein V, Ockert B, Haasters F, Hertel R, Südkamp N, Sprecher CM.
In vitro and ex vivo models to test the anti-inflammatory and regenerative effects of small molecules in osteoarthritis.
2020 GR forscht virtual (poster)Zhang P, Ziadlou R, Basoli V, Li Z, Grad S.
Anti-inflammatory effects of Losartan in human nucleus pulposus cells.
2020 Eurospine virtual (poster)Pfannkuche JJ, Li Z, Grad S, Alini M, Häckel S, Südkamp N, Schmal H, Lang G.
The influence of short-chain fatty acids on bone health.
2020 WIRM virtual (oral)Wallimann A, Thompson K, Puliese B, Magrath W, Moriarty TF, Akdis CA, O'Mahony L.
Variable-angle locked plating versus interlocked nailing for intraarticular calcaneal fractures – a biomechanical study.
2020 BOTA (poster)Stefanov A, Ivanov S, Zderic I, Baltov A, Rashkov M, Gehweiler D, Richards RG, Gueorguiev B, Enchev D.
Analysis of different screw configurations for fixation of Sanders type II B intraarticular calcaneal fractures – a biomechanical human cadaveric study.
2020 EFORT virtual (oral)Ivanov S, Stefanov A, Zderic I, Rodemund C, Schepers T, Richards RG, Raykov D, Gueorguiev B.
Individualized coronoid process reconstruction with 3D printed prosthesis provides superior stability over radial head graft reconstruction and coronoid screw fixation.
2020 EFORT virtual (oral)Pukalski Y, Barcik J, Zderic I, Yanev P, Baltov A, Rashkov M, Richards RG, Gueorguiev B, Enchev D.
Patient-specific computational optimisation of the locking screw orientation of a proximal humerus plate in osteoporotic fracture fixation.
2020 EFORT virtual (oral)Schader JF, Mischler D, Dauwe J, Gueorguiev B, Varga P.
Could the COX-2 inhibitor Celecoxib influence discogenic pain? An in vitro study with inflamed annulus fibrosus cells.
2020 EFORT virtual (poster)Häckel S, Häne S, Ma J, Li Z, Pfannkuche J, Peroglio M, Hoppe S, Benneker L, Lang G, Südkamp N, Grad S.
Assessment of the neutrophil response to a panel of synthetic and natural derived biomaterials; a novel comprehensive in vitro approach.
2020 NBTE virtual (oral)Wesdorp MA, Schwab A, Narcisi R, Eglin D, van Osch GJVM, D'Este M.
Novel acoustic wave programmed 3D vascularised cancer model in malignant pleural mesothelioma: A platform for drug screening.
Symposium STRATAGEM CA online (oral)Ananthanarayanan P, Di Marzio N, Guex AG, Alini M, Serra T, Riganti C.
Orthopedic screws insertion simulation model with real time feedback is efficient in enhancing skill and musculoskeletal memory.
2020 IOA (oral)Keltz E, Mora AJ, Fletcher J, Gueorguiev B, Keren Y.
A humanized mouse model to exhibit Staphyloccocus aureus osteomyelitis.
2020 OBIC virtual (poster)Sumrall E, Wallimann A, Hildebrand M, Zeiter S, Richards RG, Schwarz E, Moriarty TF, Muthukrishnan G.
Control of microarchitecture within biomaterial ink through 3D printing to guide cell migration.
2020 WBC virtual (oral)Schwab A, Eglin D, Alini M, D'Este M.
Improving shape stability of patient-specific calcium phosphate bone substitutes using co-axial 3D printing.
2020 WBC virtual (poster)Bagnol R, Sprecher CM, Peroglio M, Mahou M, Buchler P, Lieger O, Richards RG, Eglin D.
Controlled factorial design of experiment to optimize mechano-induced chondrogenesis of human MSCS.
2020 EORS virtual (oral)Ladner YD, Armiento AR, Snedeker JG, Stoddart MJ.
Adaptive local thresholding improves the accuracy of XTremeCT to quantify trabecular structure in the radius.
2020 EORS virtual (oral)Mys K, Varga P, Stockmans F, Gueorguiev B, Neumann V, Wyers CE, van den Bergh JPW, van Lenthe GH.
Establishment of Baltic Biomaterials Centre of Excellence.
2020 INTERREG-TERMIS Winterschool (poster)Dubnika A, Loca D, Dambrova M, Salma I, Logviss K, Alini M, Boccaccini AR, Locs J.
Establishment of the Baltic Biomaterials Centre of Excellence.
2020 WBC virtual (poster)Locs J, Dambrova M, Salma I, Logviss K, Alini M, D'Este M, Boccaccini AR, Liverani L, Loca D, Dubnika A.
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Peer-reviewed publications
Functional cell phenotype induction with TGF-beta1 and collagen-polyurethane scaffold for annulus fibrosus rupture repair.
Eur Cell Mater. 2020;39:1-17Du J, Long RG, Nakai T, Sakai D, Benneker LM, Zhou G, Li B, Eglin D, Iatridis JC, Alini M, Grad S, Li Z.
Articular Joint-Simulating Mechanical Load Activates Endogenous TGF-beta in a Highly Cellularized Bioadhesive Hydrogel for Cartilage Repair.
Am J Sports Med. 2020;48(1):210-21Behrendt P, Ladner Y, Stoddart MJ, Lippross S, Alini M, Eglin D, Armiento AR.
Orbital floor repair using patient specific osteoinductive implant made by stereolithography.
Biomaterials. 2020;233:119721Guillaume O, Geven MA, Varjas V, Varga P, Gehweiler D, Stadelmann VA, Smidt T, Zeiter S, Sprecher C, Bos RRM, Grijpma DW, Alini M, Yuan H, Richards RG, Tang T, Qin L, Yuxiao L, Jiang P, Eglin D.
Ligamentous Lisfranc injuries: analysis of CT findings under weightbearing.
Eur J Trauma Emerg Surg. 2020;epub Jan 16Penev P, Qawasmi F, Mosheiff R, Knobe M, Lehnert M, Krause F, Raykov D, Richards RG, Gueorguiev B, Klos K.
Finite element analysis of bone strength in osteogenesis imperfecta.
Bone. 2020;133:115250Varga P, Willie BM, Stephan C, Kozloff KM, Zysset PK.
Evaluation of Preclinical Models for the Testing of Bone Tissue-Engineered Constructs.
Tissue Eng Part C Methods. 2020;26(2):107-17Zeiter S, Koschitzki K, Alini M, Jakob F, Rudert M, Herrmann M.
Differential Regulation of circRNA, miRNA, and piRNA during Early Osteogenic and Chondrogenic Differentiation of Human Mesenchymal Stromal Cells.
Cells. 2020;9(2):398Della Bella E, Menzel U, Basoli V, Tourbier C, Alini M, Stoddart MJ.
Functional Biomaterials for Bone Regeneration: A Lesson in Complex Biology.
Adv Funct Mater. 2020;30:1909874Armiento AR, Hatt LP, Sanchez Rosenberg G, Thompson K, Stoddart MJ.
Production and evaluation of decellularized extracellular matrix hydrogel for cartilage regeneration derived from knee cartilage.
J Biomed Mater Res A. 2020;108(4):938-46Bordbar S, Lotfi Bakhshaiesh N, Khanmohammadi M, Sayahpour FA, Alini M,
Baghaban Eslaminejad M.Mid-term results after proximal humeral fractures following angular stable plate fixation in elderly patients-which scores can be evaluated by a telephone-based assessment?
J Orthop Surg Res. 2020;15(1):6Ziegler P, Stierand K, Bahrs C, Ahrend M-D.
Titanium and zirconium release from titanium- and zirconia implants in mini pig maxillae and their toxicity in vitro.
Dental Materials. 2020;36(3):402-12He X, Reichl F-X, Milz S, Michalke B, Wu X, Sprecher CM, Yang Y, Gahlert M, Röhling S,
Kniha H, Hickel R, Högg C.Enhanced chondrogenic phenotype of primary bovine articular chondrocytes in Fibrin-Hyaluronan hydrogel by multi-axial mechanical loading and FGF18.
Acta Biomater. 2020;105:170-9Antunes BP, Vainieri ML, Alini M, Monsonego-Ornan E, Grad S, Yayon A.
A Comparison of Osteoblast and Osteoclast In Vitro Co-Culture Models and Their Translation for Preclinical Drug Testing Applications.
Int J Mol Sci. 2020;21(3):912Sieberath A, Della Bella E, Ferreira AM, Gentile P, Eglin D, Dalgarno K.
Deriving a dose and regimen for anti-glucosaminidase antibody passive-immunisation for patients with Staphylococcus aureus osteomyelitis.
Eur Cell Mater. 2020;39:96-107Lee CC, Southgate RD, Jiao C, Gersz E, Owen JR, Kates SL, Beck CA, Xie C, Daiss JL,
Post V, Moriarty TF, Zeiter S, Schwarz EM, Muthukrishnan G.Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field.
Arch Phys Med Rehabil. 2020;101:917-23Willett NJ, Boninger ML, Miller LJ, Alvarez L, Aoyama T, Bedoni M, Brix KA, Chisari C, Christ G, Dearth CL, Dyson-Hudson TA, Evans CH, Goldman SM, Gregory K, Gualerzi A, Hart J, Ito A, Kuroki H, Loghmani MT, Mack DL, Malanga GA, Noble-Haeusslein L, Pasquina P, Roche JA, Rose L, Stoddart MJ, Tajino J, Terzic C, Topp KS, Wagner WR, Warden SJ, Wolf SL, Xie H, Rando TA, Ambrosio F.
Advanced Mg, Zn, Sr, Si Multi-Substituted Hydroxyapatites for Bone Regeneration.
Int J Nanomedicine. 2020;15:1037-58Garbo C, Locs J, D'Este M, Demazeau G, Mocanu A, Roman C, Horovitz O,
Tomoaia-Cotisel M.Growth‐Factor Free Multicomponent Nanocomposite Hydrogels That Stimulate Bone Formation.
Adv Funct Mater. 2020;30(14):1906205Okesola BO, Ni S, Derkus B, Galeano CC, Hasan A, Wu Y, Ramis J, Buttery L, Dawson JI,
D'Este M, Oreffo ROC, Eglin D, Sun H, Mata A.Extracellular matrix-mimetic composite hydrogels of cross-linked hyaluronan and fibrillar collagen with tunable properties and ultrastructure.
Carbohydr Polym. 2020;236:116042Frayssinet A, Petta D, Illoul C, Haye B, Markitantova A, Eglin D, Mosser G, D’Este M, Hélary C.
Surgical performance when inserting non-locking screws: a systematic review.
EFORT Open Rev. 2020;5(1):26-36Fletcher JWA, Wenzel L, Neumann V, Richards RG, Gueorguiev B, Gill HS, Preatoni E, Whitehouse MR.
Animal models of osteochondral defect for testing biomaterials.
Biochem Res Int. 2020;2020:9659412Meng X, Ziadlou R, Grad S, Alini M, Wen C, Lai Y, Qin L, Zhao Y, Wang X.
Evaluation of biomimetic hyaluronic-based hydrogels with enhanced endogenous cell recruitment and cartilage matrix formation.
Acta Biomater. 2020;101:293-303 (epub 2019; Nov 11)Vainieri ML, Lolli A, Kops N, D'Atri D, Eglin D, Yayon A, Alini M, Grad S, Sivasubramaniyan K,
van Osch GJVM.Development of generic Asian pelvic bone models using CT-based 3D statistical modelling.
J Orthop Translat. 2020;20:100-6 (epub 2019, Nov 4)Ahrend M-D, Noser H, Shanmugam R, Burr F, Kamer L, Kamarul T, Hügli H, Nagy A,
Richards RG, Gueorguiev-Rüegg B.Evidence-based recommendations for local antimicrobial strategies and dead space management in fracture-related infection.
J Orthop Trauma. 2020;34(1):18-29 (epub 2019; Aug 26)Metsemakers WJ, Fragomen AT, Moriarty TF, Morgenstern M, Egol KA, Zalavras C, Obremskey WT, Raschke M, McNally MA.
An Ex Vivo Bone Defect Model to Evaluate Bone Substitutes and Associated Bone Regeneration Processes.
Tissue Eng Part C Methods. 2020;26(1):56-65 (epub 2019; Dec 5)Klüter T, Hassan R, Rasch A, Naujokat H, Wang F, Behrendt P, Lippross S, Gerdesmeyer L,
Eglin D, Seekamp A, Fuchs S.Multi-Disciplinary Approaches for Cell-Based Cartilage Regeneration.
J Orthop Res. 2020;38(3):463-72 (epub 2019; Sep 3)Johnstone B, Stoddart MJ, Im GI.
Mechanochemical Adhesion and Plasticity in Multifiber Hydrogel Networks.
Adv Mater. 2020;32(8):e1905719 (epub 2019; Dec 18)Davidson MD, Ban E, Schoonen ACM, Lee MH, D'Este M, Shenoy VB, Burdick JA.
Complex biomechanical properties of non-augmented and augmented pedicle screws in human vertebrae with reduced bone density.
BMC Musculoskelet Disord. 2020;21(1):151Schulze M, Riesenbeck O, Vordemvenne T, Raschke MJ, Evers J, Hartensuer R, Gehweiler D.
Fracture-related infection: current methods for prevention and treatment.
Expert Rev Anti Infect Ther. 2020;18(4):307-21Foster AL, Moriarty TF, Trampuz A, Jaiprakash A, Burch MA, Crawford R, Paterson DL, Metsemakers WJ, Schuetz M, Richards RG.
Synergistic anti-fouling and bactericidal poly(ether ether ketone) surfaces via a one-step photomodification.
Mater Sci Eng C Mater Biol Appl. 2020;111:110811Buwalda S, Rotman S, Eglin D, Moriarty TF, Bethry A, Garric X, Guillaume O, Nottelet B.
Diagnosing Fracture-Related Infection: Current Concepts and Recommendations.
J Orthop Trauma. 2020;34(1):8-17Govaert GAM, Kuehl R, Atkins BL, Trampuz A, Morgenstern M, Obremskey WT, Verhofstad MHJ, McNally MA, Metsemakers WJ, Fracture-Related Infection Consensus Group (Metsemakers WJ, Obremskey WT, McNally MA, Athanasou N, Atkins BL, Borens O, Depypere M, Eckardt H, Egol KA, Foster W, Fragomen AT, Govaert GAM, Hungerer S, Kates SL, Kuehl R, Marais L, Mcfadyen I, Morgenstern M, Moriarty TF, Ochsner P, Ramsden A, Raschke M, Richards RG, Sancineto C, Zalavras C, Senneville E, Trampuz A, Verhofstad MHJ, Zimmerli W.)
'Pathogenesis and management of fracture-related infection' - Author's reply.
Clin Microbiol Infect. 2020;26(5):652-3Depypere M, Morgenstern M, Kuehl R, Senneville E, Moriarty TF, Obremskey WT, Zimmerli W, Trampuz A, Lagrou K, Metsemakers WJ.
Antimicrobial silver-coating for locking plates shows uneventful osteotomy healing and good biocompatibility results of an experimental study in rabbits.
Injury. 2020;51(4):830-9Arens D, Zeiter S, Nehrbass D, Ranjan N, Paulin T, Alt V.
Direct and intervertebral disc-mediated sensitization of dorsal root ganglion neurons by hypoxia and low pH.
Neurospine. 2020;17(1):42-59Ma J, Stefanoska D, Grad S, Alini M, Peroglio M.
Sodium hyaluronate supplemented culture media as a new hMSC chondrogenic differentiation media-model for in vitro/ex vivo screening of potential cartilage repair therapies.
Front Bioeng Biotechnol. 2020;8(243)Monaco G, El Haj AJ, Alini M, Stoddart MJ.
Interaction between stem cells and the microenvironment for musculoskeletal repair.
Stem Cells Int. 2020;2020:7587428Huang Y-C, Li Z, Li J, Lyu F-J.
A Multifunctional Nanocomposite Hydrogel for Endoscopic Tracking and Manipulation.
Advanced Intelligent Systems. 2020;2(3):1900105 (epub 2019; Dec 3)Augurio A, Cortelletti P, Tognato R, Rios A, Levato R, Malda J, Alini M, Eglin D, Giancane G, Speghini A, Serra T.
Morphological and biomechanical effects of annulus fibrosus injury and repair in an ovine cervical model.
JOR SPINE. 2020;3(1):e1074 (epub 2019; Dec 21)Long RG, Ferguson SJ, Benneker LM, Sakai D, Li Z, Pandit A, Grijpma DW, Eglin D, Zeiter S, Schmid T, Eberli U, Nehrbass D, Di Pauli von Treuheim T, Alini M, Iatridis JC, Grad S.
Current concepts of osteomyelitis: From pathologic mechanisms to advanced research methods.
Am J Pathol. 2020;190:1151-1163Hofstee MI, Muthukrishnan G, Atkins GJ, Riool M, Thompson K, Morgenstern M, Stoddart MJ, Richards RG, Johannes Zaat SA, Moriarty TF.
Hyaluronic acid as a (bio)ink for extrusion-based 3D printing.
Biofabrication. 2020;12:032001Petta D, D'Amora U, Ambrosio L, Grijpma D, Eglin D, D'Este M.
Multicomponent hydrogels for the formation of vascularized bone-like constructs in vitro.
Acta Biomater. 2020;109:82-94Derkus B, Okesola BO, Barrett DW, D'Este M, Chowdhury TT, Eglin D, Mata A.
Bio-fabrication: Convergence of 3D bioprinting and nano-biomaterials in tissue engineering and regenerative medicine.
Front Bioeng Biotechnol. 2020;8(326)Di Marzio N, Eglin D, Serra T, Moroni L.
Local application of a gentamicin-loaded hydrogel early after injury is superior to perioperative systemic prophylaxis in a rabbit open fracture model.
J Orthop Trauma. 2020;34:231-7 (epub 2019; Dec 6)Vallejo Diaz A, Deimling C, Morgenstern M, D'Este M, Puetzler J, Zeiter S, Arens D, Metsemakers WJ, Richards RG, Eglin D, Moriarty TF.
Computational optimisation of screw orientations for improved locking plate fixation of proximal humerus fractures.
J Orthop Translat. 2020;25:96-104Mischler D, Windolf M, Gueorguiev B, Nijs S, Varga P.
Failure after proximal humeral fracture osteosynthesis: a one year analysis of hospital-related healthcare cost.
Int Orthop. 2020;44:1217-1221Dauwe J, Walters G, Holzer LA, Vanhaecht K, Nijs S.
Intervertebral disc organ culture for the investigation of disc pathology and regeneration - benefits, limitations, and future directions of bioreactors.
Connect Tissue Res. 2020;61:304-21 (epub 2019; Sep 26)Pfannkuche JJ, Guo W, Cui S, Ma J, Lang G, Peroglio M, Richards RG, Alini M, Grad S, Li Z.
Hypoxic stress enhances extension and branching of dorsal root ganglion neuronal outgrowth.
JOR SPINE. 2020;3:e1090Ma J, Stefanoska D, Stone LS, Hildebrand M, van Donkelaar CC, Zou X, Basoli V, Grad S, Alini M, Peroglio M.
Pathogenesis and management of fracture-related infection.
Clin Microbiol Infect. 2020;26(5):572-8 (epub 2019; Aug 22)Depypere M, Morgenstern M, Kuehl R, Senneville E, Moriarty TF, Obremskey WT, Zimmerli W, Trampuz A, Lagrou K, Metsemakers WJ.
Focused high-energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture-related infection.
J Orthop Res. 2020;38(6):1351-8 (epub 2019; Dec)Puetzler J, Milstrey A, Everding J, Raschke M, Arens D, Zeiter S, Richards RG, Moriarty TF.
Arthroscopic arthrolysis leads to improved range of motion and health-related quality of life in post-traumatic elbow stiffness.
J Shoulder Elbow Surg. 2020;29:1538-1547Schreiner AJ, Schweikardt N, Gühring D, Ahrend MD, Döbele S, Ahmad SS, Baumann M, Hirschmann MT, Bozzi F, Ateschrang A.
Improving the accuracy of patient positioning for long-leg radiographs using a Taylor Spatial Frame mounted rotation rod.
Arch Orthop Trauma Surg. 2020;epub May 6Ahrend MD, Finger F, Grünwald L, Keller G, Baumgartner H.
Health-related quality of life - an underestimated factor to evaluate the treatment success after open wedge HTO surgery: prospective 6-years follow-up.
Z Orthop Unfall. 2020;epub Feb 27
Herbst M, Kuwashima U, Ahrend MD, Gueorguiev BG, Schröter S, Ihle C. Biphasic Plating – In vivo study of a novel fixation concept to enhance mechanobiological fracture healing.
Injury. 2020;51:1751-1758
Hofmann-Fliri L, Epari D, Schwyn R, Zeiter S, Windolf M. Differences between auto-fluorescence and tetracycline-fluorescence in medication-related osteonecrosis of the jaw-a preclinical proof of concept study in the mini-pig.
Clin Oral Investig. 2020;24:4625-4637
Ristow O, Nehrbass D, Zeiter S, Arens D, Moratin J, Pautke C, Hoffmann J, Freudlsperger C, Otto S. Thermo-responsive antimicrobial hydrogel for the in-situ coating of mesh materials for hernia repair.
Polymers. 2020;12:1245
Pérez-Köhler B, Pascual G, Benito-Martínez S, Bellón JM, Eglin D, Guillaume O. Preclinical ex-vivo testing of anti-inflammatory drugs in a bovine intervertebral degenerative disc model.
Front Bioeng Biotechnol. 2020;8:583
Li Z, Gehlen Y, Heizmann F, Grad S, Alini M, Richards RG, Kubosch D, Südkamp N, Izadpanah K, Kubosch EJ, Lang G. Tissue mimetic hyaluronan bioink containing collagen fibers with controlled orientation modulating cell migration and alignment.
Mater Today Bio. 2020;7:100058
Schwab A, Helary C, Richards RG, Alini M, Eglin D, D'Este M. Bioprinting tissue analogues with decellularized extracellular matrix bioink for regeneration and tissue models of cartilage and intervertebral discs.
Adv Funct Mater. 2020;30:1909044
Vernengo AJ, Grad S, Eglin D, Alini M, Li Z. Development of a novel biodegradable porous iron-based implant for bone replacement.
Sci Rep. 2020;10(1):9141
Wegener B, Sichler A, Milz S, Sprecher C, Pieper K, Hermanns W, Jansson V, Nies B, Kieback B, Müller PE, Wegener V, Quadbeck P. Proinflammatory intervertebral disc cell and organ culture models induced by tumor necrosis factor alpha.
JOR SPINE. 2020;3:e1104
Du J, Pfannkuche JJ, Lang G, Häckel S, Creemers LB, Alini M, Grad S, Li Z. Anti-inflammatory and chondroprotective effects of Vanillic acid and Epimedin C in human osteoarthritic chondrocytes.
Biomolecules. 2020;10(6):932
Ziadlou R, Barbero A, Martin I, Wang X, Qin L, Alini M, Grad S. The influence of biomechanical stability on bone healing and fracture-related infection: the legacy of Stephan Perren.
Injury. 2020;epub Jun 26
Foster AL, Moriarty TF, Zalavras C, Morgenstern M, Jaiprakash A, Crawford R, Burch M-A, Boot W, Tetsworth K, Miclau T, Ochsner P, Schuetz MA, Richards RG, Metsemakers W-J. In vivo test of a radiography-based navigation system for control of derotational osteotomies.
J Orthop Res. 2020;epub Jun 21
Grünwald L, Schröter S, Windolf M, Gueorguiev B, Richards RG, Buschbaum J. Comparison of optimal screw configurations in two locking plate systems for proximal humerus fixation - a finite element analysis study.
Clin Biomech. 2020;78:105097
Mischler D, Babu S, Osterhoff G, Pari C, Fletcher J, Windolf M, Gueorguiev B, Varga P. A drug holiday reduces the frequency and severity of Medication Related Osteonecrosis of the jaw in a minipig model.
J Bone Miner Res. 2020;35: 2179-2192
Otto S, Pautke C, Arens D, Poxleitner P, Eberli U, Nehrbass D, Zeiter S, Stoddart MJ. Predicting and promoting human bone marrow MSC chondrogenesis by way of TGFβ receptor profiles: Toward personalized medicine.
Front Bioeng Biotechnol. 2020;8(618)
Rothweiler R, Basoli V, Duttenhoefer F, Kubosch D, Schmelzeisen R, Johnstone B, Alini M, Stoddart MJ. General treatment principles for fracture-related infection: recommendations from an international expert group.
Arch Orthop Trauma Surg. 2020;140(8):1013-27 (epub 2019; Oct 29)
Metsemakers WJ, Morgenstern M, Senneville E, Borens O, Govaert GAM, Onsea J, Depypere M, Richards RG, Trampuz A, Verhofstad MHJ, Kates SL, Raschke M, McNally MA,Obremskey WT, Fracture-Related Infection Group. Mechanical and biological characterization of a composite annulus fibrosus repair strategy in an endplate delamination model.
JOR SPINE. 2020;epub Jul 16( ):e1107
Alexeev D, Cui S, Grad S, Li Z, Ferguson SJ. Design of tunable gelatin-dopamine based bioadhesives.
Int J Biol Macromol. 2020;164:1384-1391
Gowda AHJ, Bu Y, Kudina O, Kanala VK, Bohara RA, Eglin D, Pandit A.
Preexisting and treated concomitant ankle instability does not compromise patient-reported outcomes of solitary osteochondral lesions of the talus treated with matrix-induced bone marrow stimulation in the first postoperative year: data from the German Cartilage Registry (KnorpelRegister DGOU).
Knee Surg Sports Traumatol Arthrosc. 2020;epub Jul 31
Ahrend MD, Aurich M, Becher C, Ateschrang A, Schröter S, Walther M, Gottschalk O, Plaass C, Ettinger S, Zinser W, Körner D.
Advanced CT visualization improves the accuracy of orthopaedic trauma surgeons and residents in classifying proximal humeral fractures: a feasibility study.
Eur J Trauma Emerg Surg. 2020;epub Aug 6
Dauwe J, Mys K, Putzeys G, Schader JF, Richards RG, Gueorguiev B, Varga P, Nijs S.
Mechanical stress inhibits early stages of endogenous cell mgration: A pilot study in an ex vivo osteochondral model.
Polymers. 2020;12:1754
Vainieri ML, Alini M, Yayon A, van Osch GJVM, Grad S.
Development of surgical tools and procedures for experimental preclinical surgery using computer simulations and 3D printing.
iJOE. 2020;16(9):183-95
Barcik J, Ernst M, Schwyn R, Freitag L, Dlaska CE, Drenchev L, Todorov S, Skulev H, Epari DR, Zeiter S, Gueorguiev B.
Higher stability and more predictive fixation with the Femoral Neck System versus Hansson Pins in femoral neck fractures Pauwels II.
J Orthop Translat. 2020;24:88-95
Schopper C, Zderic I, Menze J, Müller D, Rocci M, Knobe M, Shoda E, Richards RG, Gueorguiev B, Stoffel K.
3-dimensional in vitro Staphylococcus aureus abscess communities display antibiotic tolerance and protection from neutrophil clearance.
Infect Immun. 2020;88:e00292-20
Hofstee MI, Riool M, Terjajevs I, Thompson K, Stoddart MJ, Richards RG, Zaat SAJ, Moriarty TF.
Proximal humeral fracture osteosynthesis in Belgium: a retrospective population-based epidemiologic study.
Eur J Trauma Emerg Surg. 2020;epub Aug 20
Dauwe J, Danker C, Herteleer M, Vanhaecht K, Nijs S.
Survey on sheep usage in biomedical research
Animals. 2020;10:1528
Berset CM, Lanker U, Zeiter S. Cement augmentation of calcar screws may provide the greatest reduction in predicted screw cut-out risk for proximal humerus plating based on validated parametric computational modelling.
Bone Joint Res. 2020;9(9):534-42
Varga P, Inzana JA, Fletcher JWA, Hofmann-Fliri L, Runer A, Südkamp NP, Windolf M. Printability and shape fidelity of bioinks in 3D bioprinting.
Chem Rev. 2020;120:11028-11055
Schwab A, Levato R, D'Este M, Piluso S, Eglin D, Malda J. Wrist movements induce torque and lever force in the scaphoid: an ex vivo study.
J Orthop Surg Res. 2020;15(1):368
Erhart J, Unger E, Schefzig P, Varga P, Hagmann M, Ristl R, Hajdu S, Gormasz A, Sadoghi P, Mayr W. Ankle joint pressure in supination-external rotation injuries: a biomechanical study in an unrestrained cadaver model.
Foot Ankle Spec. 2020;epub Sep 2
Fösel AC, Seidel A, Attinger MC, Zderic I, Gueorguiev B, Krause FG. Local Bacteriophage Delivery for Treatment and Prevention of Bacterial Infections.
Front Microbiol. 2020;11:2276
Rotman SG, Sumrall E, Ziadlou R, Grijpma DW, Richards RG, Eglin D, Moriarty TF. Transdermal Fentanyl Uptake at Two Different Patch Locations in Swiss White Alpine Sheep.
Animals. 2020;10(9):1675
Buchholz T, Hildebrand M, Heider A, Stenger V, Arens D, Spadavecchia C, Zeiter S. Biomechanical analysis of peri-implant fractures in short versus long cephalomedullary implants following pertrochanteric fracture consolidation.
Injury. 2020;epub Sept 18
Breceda A, Sands A, Zderic I, Schopper C, Schader J, Gehweiler D, Mischler D, Richards RG, Gueorguiev B. Poly(Aspartic Acid) Functionalized Poly(ϵ-Caprolactone) Microspheres with Enhanced Hydroxyapatite Affinity as Bone Targeting Antibiotic Carriers.
Pharmaceutics. 2020;12:E:885
Rotman SG, Moriarty TF, Nottelet B, Grijpma DW, Eglin D, Guillaume O. Comparison of Ligament-Repair Techniques for the Syndesmosis: A Simulated Cadaveric Weight-Bearing Computed Tomography Analysis.
J Foot Ankle Surg. 2020;59:1156-1161
Hagen JE, Rausch S, Simons P, Lenz M, Knobe M, Roth KE, Gueorguiev B, Richards RG, Klos K. Smart implants in fracture care – only buzzword or real opportunity?
Injury. 2020;epub Sept 17
Ernst M, Richards RG, Windolf M. Sound-induced morphogenesis of multicellular systems for rapid orchestration of vascular networks.
Biofabrication. 2020;13:015004
Petta D, Basoli V, Pellicciotta D, Tognato R, Barcik JP, Arrigoni C, Della Bella E, Armiento AR, Candrian C, Richards RG, Alini M, Moretti M, Eglin D, Serra T. From creative thinking to scientific principles in clinical practice.
Injury. 2020;epub Sept 29
Lambert S, Mischler D, Windolf M, Regazzoni P, Fernandez Dell'Oca A, Gueorguiev B, Varga P. The tissue-renin-angiotensin-system of the human intervertebral disc.
Eur Cell Mater. 2020;40:115-32
Li Z, Wystrach L, Bernstein A, Grad S, Alini M, Richards RG, Kubosch D, Südkamp N, Izadpanah K, Kubosch EJ, Lang G. Fentanyl Plasma Concentrations after Application of a Transdermal Patch in Three Different Locations to Refine Postoperative Pain Management in Rabbits.
Animals. 2020;10:1778
Mirschberger V, von Deimling C, Heider A, Spadavecchia C, Rohrbach H, Zeiter S. Systemic Manifestations of the Periodontal Disease: A Bibliometric Review.
Molecules. 2020;25:4508
Ahmad P, Arshad AI, Della Bella E, Khurshid Z, Stoddart M. Influence of the Reamer-Irrigator-Aspirator diameter on femoral bone strength and amount of harvested bone graft – a biomechanical cadaveric study.
Injury. 2020;51:2846-2850
Schmitz N, Gehweiler D, Wähnert D, Zderic I, Grünwald L, Richards RG, Gueorguiev B, Raschke M. Non-viral Gene Delivery of Interleukin-1 Receptor Antagonist Using Collagen-Hydroxyapatite Scaffold Protects Rat BM-MSCs from IL-1β-Mediated Inhibition of Osteogenesis.
Front Bioeng Biotechnol. 2020;8:1180
Lackington WA, Gomez-Sierra MA, González-Vázquez A, O’Brien FJ, Stoddart MJ, Thompson K. Inhibition of hypertrophy and improving chondrocyte differentiation by MMP-13 inhibitor small molecule encapsulated in alginate-chondroitin sulfate-platelet lysate hydrogel.
Stem Cell Res Ther. 2020;11:436
Jahangir S, Eglin D, Potter N, Ravari MK, Stoddart MJ, Samadikuchaksaraei A, Alini M, Eslaminejad MB, Safa M. Visible light-induced 3D bioprinting technologies and corresponding bioink materials for tissue engineering: A review.
Engineering. 2020;epub Sep 20
Zheng Z, Eglin D, Alini M, Richards RG, Qin L, Lai Y. Effect of the Addition Frequency of 5-Azacytidine in Both Micro- and Macroscale Cultures.
Cell Mol Bioeng. 2020;epub Oct 06
Kadekar S, Barbe L, Stoddart M, Varghese OP, Tenje M, Mestres G. Screw placement in two different implants for proximal humeral fractures regarding regional differences in bone mineral density: An anatomical study.
Injury. 2020;epub Oct 10
Holweg P, Dauwe J, Grechenig P, Holter M, Staresinic M, Feigl G, Bakota B. New Insights into Osteointegration and Delamination from a Multidisciplinary Investigation of a Failed Hydroxyapatite-Coated Hip Joint Replacement.
Materials. 2020;13:4713
Schönweger F, Sprecher CM, Milz S, Dommann-Scherrer C, Meier C, Dommann A, Neels A, Wahl P. Applications of Bone Morphogenetic Proteins in Dentistry: A Bibliometric Analysis.
Biomed Res Int. 2020;2020:5971268
Ahmad P, Della Bella E, Stoddart MJ. The relation between fracture activity and bone healing with special reference to the early healing phase – a preclinical study.
Injury. 2020;epub Oct 10
Windolf M, Ernst M, Schwyn R, Arens D, Zeiter S. Quantification of 3D microstructural parameters of trabecular bone is affected by the analysis software.
Bone. 2020;epub Oct 12
Mys K, Varga P, Stockmans F, Gueorguiev B, Wyers CE, van den Bergh JPW, van Lenthe GH. Morphology of bony callus growth in healing of a sheep tibial osteotomy.
Injury. 2020;epub Oct 19
Wilson CJ, Epari DR, Ernst M, Arens D, Zeiter S, Windolf M. Biomechanical evaluation of retrograde docking nailing to a total hip arthroplasty stem in a periprosthetic femur fracture model.
Injury. 2020;epub Oct 19
Lenz M, Hofmann-Fliri L, Kasper LA, Varga P, Zderic I, Gehweiler D, Klos K, Hofmann GO, Stoffel K, Gueorguiev B. Cortical parameters predict bone strength at the tibial diaphysis, but are underestimated by HR-pQCT and μCT compared to histomorphometry.
J Anat. 2020;epub Oct 20
Schmidutz F, Milz S, Schiuma D, Richards RG, Windolf M, Sprecher CM. Two reconstruction plates provide superior stability of displaced midshaft clavicle fractures in comparison to single plating – A biomechanical study.
Clin Biomech. 2020;80:105199
Yanev P, Zderic I, Pukalski Y, Enchev D, Rashkov M, Varga P, Gehweiler D, Richards RG, Gueorguiev B, Baltov A. Screw-in-screw fixation of fragility sacrum fractures provides high stability without loosening – Biomechanical evaluation of a new concept.
J Orthop Res. 2020;epub Oct 24
Zderic I, Wagner D, Schopper C, Lodde M, Richards RG, Gueorguiev B, Rommens P, Acklin YP. An impaired healing model of osteochondral defect in papain-induced arthritis.
J Orthop Translat. 2020;epub Sep 22
Meng X, Grad S, Wen C, Lai Y, Alini M, Qin L, Wang X. One strike loading organ culture model to investigate the post-traumatic disc degenerative condition.
J Orthop Translat. 2020;epub Oct 20
Zhou Z, Cui S, Du J, Richards RG, Alini M, Grad S, Li Z. Editorial: MSC Signaling in Regenerative Medicine.
Front Bioeng Biotechnol. 2020;8:1276
Stoddart MJ, Hofmann S, Holnthoner W. Optimization of hyaluronic acid-tyramine/silk-fibroin composite hydrogels for cartilage tissue engineering and delivery of anti-inflammatory and anabolic drugs.
Mater Sci Eng C Mater Biol Appl. 2020;epub Nov 5:111701
Ziadlou R, Rotman S, Teuschl A, Salzer E, Barbero A, Martin I, Alini M, Eglin D, Grad S. The tissue renin-angiotensin system (tRAS) and the impact of its inhibition on inflammation and bone loss in the periodontal tissue.
Eur Cell Mater. 2020;40:203-226
Saravi B, Lang G, Ülkümen S, Burchard T, Weihrauch V, Patzelt S, Boeker M, Li Z, Woelber JP. Innovative Tissue-Engineered Strategies for Osteochondral Defect Repair and Regeneration: Current Progress and Challenges.
Adv Healthc Mater. 2020;9:2001008
Zhou L, van Osch GJVM, Malda J, Stoddart MJ, Lai Y, Richards RG, Ki-Wai Ho K, Qin L. Development and characterization of a predictive microCT-based non-union model in Fischer F344 rats.
Arch Orthop Trauma Surg. 2020;epub Nov 10
Hildebrand M, Herrmann M, Gieling F, Gehweiler D, Mischler D, Verrier S, Alini M, Zeiter S, Thompson K. Efficacy of antimicrobial agents delivered to hernia meshes using an adaptable thermo-responsive hyaluronic acid-based coating.
Hernia. 2020;24(6):1201-10 (epub 2019; Nov 28)
Pérez-Köhler B, Linardi F, Pascual G, Bellón JM, Eglin D, Guillaume O.
Stable reference genes for qPCR analysis in BM-MSCs undergoing osteogenic differentiation within 3D hyaluronan-based hydrogels.
Int J Mol Sci. 2020;21(23):9195
Hasler J, Hatt LP, Stoddart MJ, Armiento AR.
Longitudinal time-lapse in vivo micro-CT reveals differential patterns of peri-implant bone changes after subclinical bacterial infection in a rat model.
Sci Rep. 2020;10(1):20901
Stadelmann VA, Thompson K, Zeiter S, Camenisch K, Styger U, Patrick S, McDowell A, Nehrbass D, Richards RG, Moriarty TF.
Biomechanical evaluation of the docking nail concept in periprosthetic fracture fixation around a stemmed total knee arthroplasty.
J Biomech. 2020;epub Nov 18:110109
Lenz M, Acklin YP, Kasper LA, Mischler D, Varga P, Zderic I, Gehweiler D, Klos K, Gueorguiev B, Stoffel K.
Variations in non-locking screw insertion conditions generate unpredictable changes to achieved fixation tightness and stripping rates.
Clin Biomech. 2020;80:105201
Fletcher JWA, Neumann V, Wenzel L, Gueorguiev B, Richards RG, Gill HS, Whitehouse MR, Preatoni E.
Antimicrobial resistance, the COVID-19 pandemic, and lessons for the orthopaedic community.
J Bone Joint Surg Am. 2020;epub Dec 2
Metsemakers W-J, Zalavras C, Schwarz EM, Chen AF, Trampuz A, Moriarty TF.
Identification and characterization of serum microRNAs as biomarkers for human disc degeneration: An RNA sequencing analysis.
Diagnostics. 2020;10(12):1063
Cui S, Zhou Z, Liu X, Richards RG, Alini M, Peng S, Liu S, Zou X, Li Z, Grad S.
Development of bone seeker-functionalised microspheres as a targeted local antibiotic delivery system for bone infections.
J Orthop Translat. 2020;21:136-45
Rotman SG, Thompson K, Grijpma DW, Richards RG, Moriarty TF, Eglin D, Guillaume O.
The alveolar ridge splitting technique on maxillae: A biomechanical human cadaveric investigation.
Biomed Res Int. 2020;8894471
Duttenhoefer F, Varga P, Jenni D, Grünwald L, Thiemann L, Gueorguiev B, Stricker A.
Asymmetry of the pelvic ring evaluated by CT-based 3D statistical modeling.
J Anat. 2020;epub Dec 31
Handrich K, Kamer L, Mayo K, Sawaguchi T, Noser H, Arand C, Wagner D, Rommens PM.
Single-stage revision of MRSA orthopedic device-related infection in sheep with an antibiotic-loaded hydrogel.
J Orthop Res. 2020;epub Dec 11
Foster AL, Boot W, Stenger V, D'Este M, Jaiprakash A, Eglin D, Zeiter S, RG, Moriarty TF.
Stripping torques in human bone can be reliably predicted prior to screw insertion with optimum tightness being found between 70% and 80% of the maximum.
Bone Joint Res. 2020;9(8):493-500
Fletcher JWA, Zderic I, Gueorguiev B, Richards RG, Gill HS, Whitehouse MR, Preatoni E.
Impact of low bone mass and antiresorptive therapy on antibiotic efficacy in a rat model of orthopedic device-related infection.
J Orthop Res. 2020;epub Dec 15
Thompson K, Freitag L, Styger U, Camenisch K, Zeiter S, Arens D, Richards RG, Moriarty TF, Stadelmann VA.
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Theses and dissertations
Preclinical testing of TNF-α inhibitor Etanercept in a bovine organ culture model of active discopathy.
2020 Albert-Ludwigs-Universität, Freiburg i. Br. (G. Lang, S. Grad, Z. Li) – MD / Dr. med.Heizmann F.
Minimally invasive surgery in displaced intraarticular fractures of the calcaneus.
2020 Medical University of Varna (I. Raykov, B. Gueorguiev) – PhDIvanov S.
Medication related osteonecrosis of the jaw in minipig model: parameters to develop a macroscopic, radiologic and microscopic grading scheme.
2020 Universität Zürich (Kircher P, Zeiter S) – DVM / Dr med vetNowicki BH.
Biological therapy and tissue engineering approaches for the treatment of osteoarthritis.
2020 Universität Basel (I. Martin, S. Grad) – PhDZiadlou R.
Das Renin-Angiotensin-System der humanen Bandscheibe.
2020 Albert-Ludwigs-Universität Freiburg i. Br. (G. Lang, S. Grad) – MD / Dr medWystrach LWG.
Treating Discogenic Pain by Reducing Dorsal Root Ganglion Cell Sensitization using the COX-2 Inhibitor Celecoxib – An in vitro Study with Inflammatory Cytokine Treated Annulus Fibrosus Cells.
2020 ETH Zürich (Z. Li, J. Ma) – MSc ETHHäne SI.
3D Printed Multi-Scale Scaffolds with Topographical Guidance for Annulus Fibrosus Regeneration.
2020 ETH Zürich (A. Vernengo, S. Grad, S. Ferguson) – MSc ETH HSTKluser N.
Identification of a suitable RNA extraction method and stable reference genes for qRT-PCR in 3D osteogenic cultures of mesenchymal stromal cells
2020 ETH Zürich (MJ. Stoddart, A.R. Armiento, SJ. Ferguson) - MSc ETH HSTHasler J.
Stem cell homing towards degenerative intervertebral discs: characterization of the migrating subpopulation and its regenerative potential.
2020 Universität Bern (M. Alini, L.M. Benneker, M. Peroglio) – MD & PhDWangler S.
Transdermal Fentanyl uptake at two different patch locations in Swiss white alpine sheep.
2020 Universität Bern (C. Spadadvecchia, S. Zeiter) – DVM / Dr med vetBuchholz T.
Biomaterial approaches for the treatment and prevention of orthopaedic infections.
2020 University of Twente (D.W. Grijpma, D. Eglin) – PhDRotman SG.
2019
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Abstracts published in journals
2019 Preclinical Testing of Anti-Inflammatory Compounds Using a Whole Intervertebral Disc Organ Culture Model.
Global Spine J. 2019;9(2 Suppl ):97S-8S
(Global Spine Congress)Lang G, Li Z, Gehlen Y, Heizmann F, Kubosch D, Südkamp N, Alini M, Grad S. 2019 Homing of Mesenchymal Stem Cells Into Degenerated Intervertebral Discs: An Alternative to Stem Cell Injection?
Global Spine J. 2019;9(2 Suppl):198S-9S
(Global Spine Congress / poster)Wangler S, Peroglio M, Li Z, Menzel U, Benneker LM, Richards RG, Alini M, Grad S. 2019 One-Way Street Disc Degeneration? An Investigation of Hydrogel and Fibroblast Growth Factor 18 (FGF-18) for Intervertebral Disc Regeneration.
Global Spine J. 2019;9(2 Suppl):341S-2S
(Global Spine Congress / poster)Haeckel S, Li Z, Yayon A, Hoppe S, Benneker L, Alini M, Grad S. 2019 Ethnical variation in pelvic anatomy – a cohort analysis of European and Japanese pelves based on a 3D statistical CT model.
Eur J Trauma Emerg Surg. 2019;45(Suppl 1):S40-1 (ECTES)Arand C, Wagner D, Noser H, Kamer L, Richards RG, Sawaguchi T, Rommens PM. 2019 The effect of subtalar motion on calcaneal osteotomies.
Swiss Med Wkly. 2019;149(Suppl 236):9S
(Swiss Orthopaedics)Krause F, Zderic I, Gueorguiev B, Schmid T. 2019 One-way Street Disc Degeneration? An Investigation of Hydrogel and Fibroblast Growth Factor 18 (FGF-18) for Intervertebral Disc Regeneration.
Swiss Med Wkly. 2019;149(Suppl 236):25-6S
(Swiss Orthopaedics)Häckel S, Li Z, Yayon A, Zolfaghar M, Hoppe S, Benneker LM, Alini M, Grad S. 2019 Grad S, Wangler S, Peroglio M, Menzel U, Benneker LM, Haglund L, Sakai D, Alini M. 2019 Lackington W, Gomez M, Hildebrand M, Alini M, Zeiter S, Thompson K, . 2019 Pützler J, Alexander M, Everding J, Raschke MJ, Arens D, Zeiter S, Richards RG, Moriarty TF. 2019 Burch M-A, Zeiter S, Richards RG, Moriarty TF, Thompson K. 2019 Boot W, Foster AL, Zeiter S, Schmid T, D'Este M, Eglin D, Richards RG, Moriarty TF. 2019 Arens D, Zeiter S, Paulin T, Ranjan N, Alt V. 2019 In vitro analysis of the protective effect of Losartan in the treatment of degenerative disc disease.
Eur Spine J. 2019;28(11):2666 (DWK / oral)Pfannkuche J, Kubosch D, Südkamp N, Alini M, Grad S, Li Z, Lang G. -
Books and book chapters
2019 Bacterial Interactions With PEEK.
In: Kurtz SM (ed.). PEEK Biomaterials Handbook (Second Edition)
Elsevier 2019; p. 121-45Hickok NJ, Rochford ETJ, Jaekel DJ, Richards RG, Moriarty TF, Poulsson AHC. 2019 Surface Modification Techniques of PEEK, Including Plasma Surface Treatment.
In: Kurtz SM (ed.). PEEK Biomaterials Handbook (Second Edition)
Elsevier 2019; p. 179-201Poulsson AHC, Eglin D, Richards RG. 2019 Developing Bioreactors to Host Joint-Derived Tissues That Require Mechanical Stimulation.
in:Reis RL (ed.). Encyclopedia of Tissue Engineering and Regenerative Medicine, Elsevier 2019; p. 261-280Gantenbein B, Frauchiger DA, May RD, Bakirci E, Rohrer U, Grad S. 2019 Osseointegration of Permanent and Temporary Orthopedic Implants
in: Narayan R.(ed.). Encyclopedia of Biomedical Engineering. Elsevier 2019, pp. 257-269
Hayes J.S., Richards R.G. -
Conference presentations
2019 Long Term Outcomes of Biomaterial-Mediated Repair of Focal Cartilage Defects in a Large Animal Model.
2019 ORSSennett ML, Friedman JM, Ashley BS, Stoeckl BD, Patel JM, Alini M, Cucchiarini M, Eglin D, Madry H, Mata A, Semino C, Stoddart M, Moutos FT, Estes BT, Guilak F, Mauck RL, Dodge GR. 2019 Antibiotic-Eluting Collagen-Hydroxyapatite Scaffolds Eradicate Infection and Facilitate Bone Healing in a Rabbit Model of Osteomyelitis.
2019 ORSSheehy EJ, von Diemling C, Moriarty TF, O'Brien FJ. 2019 Highly tunable hyaluronan-derived hydrogel to study mechanoregulated chondrogenesis of human MSCs.
2019 ORS (poster)Behrendt P, Ladner Y, Stoddart MJ, Lippross S, Alini M, Eglin D, Armiento AR. 2019 Impact of NSAID administration on Staphylococcus epidermidis implant-related infection and response to antibiotic treatment.
2019 ORS (poster)Thompson K, Arens D, Eberli U, Richards RG, Stadelmann VA, Moriarty TF. 2019 Effects of mechanical stimulation combined with FGF-18 on bovine chondrocytes embedded in a novel Fibrin:Hyaluronan hydrogel.
2019 ORS (poster)Antunes BP, Vainieri ML, Monsonego-Ornan E, Alini M, Grad S, Yayon A. 2019 BMP2 and TGF-ß differentially cooperate during synovial derived stem cell chondrogenesis in a dexamethasone dependant manner.
2019 ORS (ICORS best posters)Basoli V, Kovermann N, Della Bella E, Alini M, Lischer C, Schmal H, Kubosch EJ, Stoddart MJ. 2019 The Tissue-Renin-Angiotensin-System of the Human Intervertebral Disc.
2019 ORS (DGOU best poster)Lang G, Wystrach L, Kubosch D, Südkamp N, Bernstein A, Alini M, Grad S, Li Z. 2019 Delaminierung der Hydroxylapatit-Beschichtung des Schaftes 14 Monate nach Implantation einer Hüft-Totalendoprothese.
2019 Endoprothetik (poster)Wahl P, Meier C, Dommann A, Neels A, Sprecher CM. 2019 Cone-Beam computed tomography as a fast alternative for high-resolution peripheral computed tomography.
2019 QMSKIMys K, Varga P, Stockmans F, Gueorguiev B, Wyers CE, van den Bergh JPW, van Lenthe GH. 2019 X-ray scattering is limited in cone-beam computed tomography of extremities.
2019 QMSKIMys K, Zhang G, Stockmans F, Wyers CE, van den Bergh JPW, van Lenthe GH. 2019 Influence of the analysis software to calculate direct bone structural parameters.
2019 QMSKI (poster)Mys K, Varga P, Stockmans F, Gueorguiev B, Wyers CE, van den Bergh JPW, van Lenthe GH. 2019 A sound-induced technology for multiscale organization of perfusable micro-vessels networks.
2019 EMBO/ EMBL Symposium (poster)Serra T. 2019 Hydroxyapatite coating delamination – A case report 14 months after total hip arthroplasty.
2019 Meet the Expert (poster)Wahl P, Meier C, Milz S, Dommann A, Neels A, Sprecher CM. 2019 Pre-clinical testing of anti-inflammatory compounds in an intervertebral disc organ culture model.
2019 BioSpineLang G, Gehlen Y, Heizmann F, Kubosch D, Südkamp N, Alini M, Grad S, Li Z. 2019 MSC homing facilitates IVD cell survival, proliferation and enhances the Tie2 positive IVD progenitor cell subpopulation.
2019 BioSpineWangler S, Peroglio M, Menzel U, Benneker LM, Haglund L, Sakai D, Alini M, Grad S. 2019 Development and characterization of 3D printed scaffolds for annulus fibrosus regeneration.
2019 BioSpine (poster)Vernengo A, Li Z, Grad S, Eglin D, Alini M. 2019 Different isolation methods for nucleus pulposus progenitor cells.
2019 BioSpine (poster)Frauchiger DA, Tekari A, May R, Džafo E, Chan SCW, Stoyanov J, Bertolo A, Zhang X, Sakai D, Schol J, Grad S, Tryfonidou M, Benneker LM, Gantenbein B. 2019 Einfluss verschiedener Verletzungen des Lisfranc-Komplexes - Eine CT basierte Kadaverstudie.
2019 DAF (poster)Klos K, Simons P, Gueorguiev B, Richards RG, Krause F, Knobe M, Penev P. 2019 A novel 3-dimensional multicellular in vitro model for Staphylococcus aureus microcolony interaction with neutrophils.
2019 WIRM (poster)Hofstee M, Richards RG, Moriarty TF, Zaat SAJ. 2019 The influence of microbial-derived metabolites on bone health.
2019 WIRM (poster)Wallimann A, Thompson K, Moriarty TF, Akdis CA, O'Mahony L. 2019 Investigation of Traditional Chinese Medicine (TCM) Bioactive Compounds Towards Treatment of Osteoarthritis.
2019 Day of Life Sciences (poster)Ziadlou R, Grad S, Stoddart M, Wang X, Qin L, Barbero A, Martin I, Alini M. 2019 Hypoxic stress enhances extension and branching of sensory neuronal outgrowth: a comparison between in vitro and ex vivo model.
2019 NeuPSIG (poster)Ma J, Stefanoska D, Grad S, Alini M, Peroglio M. 2019 Low pH culture of dorsal root ganglion cells as an in vitro model to study pathological changes involved in the development of neuropathic pain.
2019 NeuPSIG (poster)Ma J, Stefanoska D, Grad S, Alini M, Peroglio M. 2019 Ligamentous Lisfranc injuries. CT study with weightbearing on cadavers.
2019 BFASPenev P, Simons P, Qawasmi F, Gueorguiev B, Richards RG, Krause F, Knobe M, Klos K. 2019 Novel dynamic plating concept to improve the biomechanics of internal fixation.
2019 AOTAP (Best paper award)Gurung R, Windolf M, Schwyn R, Zeiter S, Epari D, Hofmann-Fliri L. 2019 Serra T, Pellicciotta D, Basoli V, Della Bella E, Armiento AR, Richards RG, Alini M, Eglin D. 2019 Surface modification of drug delivery microspheres to enhance affinity to bone.
2019 SSB+RM (poster)Rotman SG, Grijpma DW, Richards RG, Moriarty TF, Eglin D, Guillaume O. 2019 Schwab A, Ambrosio L, Alini M, Eglin D, D'Este M. 2019 Vernengo AJ, Li Z, Grad S, Eglin D, Alini M. 2019 Dal Fabbro LT, Lerf R, Schmid B, Baumgartner D, Vainieri L. 2019 Alini M. 2019 Eglin D. 2019 Role of kinematic load on cell behavior.
2019 TERMIS EUStoddart MJ. 2019 Basoli V, Della Bella E, Alini M, Stoddart MJ. 2019 Della Bella E, Basoli V, Alini M, Stoddart MJ. 2019 Du J, Long RG, Sakai D, Benneker LM, Iatridis JC, Alini M, Grad S, Li Z. 2019 Controlled delivery of IL-1Ra to enhance long bone healing.
2019 TERMIS EULackington W, Hildebrand M, Alini M, Zeiter S, Stoddart M, Thompson K. 2019 Monaco G, Alini M, El Haj A, Stoddart MJ. 2019 Pellicciotta D, Richards RG, Eglin D, Alini M, Serra T. 2019 Rotman S, Wang M, Yang S, Grijpma DW, Richards RG, Moriarty TF, Eglin D, Tang TT, Guillaume O. 2019 Vainieri ML, Lolli A, Sivasubramaniyan K, Eglin D, Yayon A, Alini M, Grad S, van Osch G. 2019 Ziadlou R, Grad S, Stoddart M, Wang X, Qin L, Barbero A, Martin I, Alini M. 2019 Schwab A, Ambrosio L, Alini M, Eglin D, D'Este M. 2019 Dasen B, Guerrero J, Scherberich A, Verrier S, Martin I, Philippova M. 2019 Lolli A, Sivasubramaniyan K, Vainieri ML, Kops N, Yayon A, van Osch GJVM. 2019 Pereira AR, Gehweiler D, Trivanovic D, Kreuzahler T, Herrmann M. 2019 Frauchiger DA, May RD, Džafo E, Zhang X, Stoyanov J, Bertolo A, Benneker LM, Sakai D, Grad S, Tryfonidou M, Gantenbein B. 2019 Wangler S, Peroglio M, Menzel U, Benneker L, Haglund L, Sakai D, Alini M, Grad S. 2019 High-fidelity orbital floor repair using patient specific osteoinductive implant made by stereolithography.
2019 IS2MEglin D. 2019 Healing of large bone defects.
2019 GTRMVerrier S. 2019 The effect of subtalar motion on calcaneal osteotomies.
2019 EFORTKrause F, Zderic I, Gueorguiev B, Schmid T. 2019 Externalized locked plating of unstable proximal tibia fractures can provide sufficient stability under partial weightbearing. A finite element study.
2019 EFORTMakelov B, Silva JD, Apivatthakakul T, Gueorguiev B, Varga P. 2019 The effect of different insertion variables on achieved screw tightness and stripping rates for non-locking screws.
2019 EFORTNeumann V, Fletcher J, Wenzel L, Gueorguiev B, Richards RG, Whitehouse M, Gill H, Preatoni E. 2019 Evidence-based generic Asian pelvic bone models for research, development and teaching using CT-based 3D statistical modeling.
2019 EFORT (poster)Ahrend M-D, Noser H, Shanmugam R, Kamer L, Burr F, Hügli H, Zaman TK, Richards RG, Gueorguiev B. 2019 Antimicrobial silver-modification for locking plates shows uneventful fracture healing and good biocompatibility – Results of an experimental study in rabbits.
2019 EFORT (poster)Arens D, Zeiter S, Ranjan N, Paulin T, Alt V. 2019 Assessing screw tightness and stripping rates achieved by orthopaedic surgeons and researchers, including using an augmented screwdriver.
2019 EFORT (poster)Fletcher J, Neumann V, Wenzel L, Gueorguiev B, Richards RG, Whitehouse M, Gill H, Preatoni E. 2019 Microcirculation after trochanteric femur fractures: A prospective cohort study using non-invasive laser-doppler spectrophotometry.
2019 EFORT (poster)Ganse B, Böhle F, Pastor T, Gueorguiev B, Altgassen S, Gradl G, Kim B-S, Modabber A, Nebelung S, Hildebrand F, Knobe M. 2019 The effect of grip configuration on achieved non-locking screw tightness.
2019 EFORT (poster)Jorge-Mora A, Keltz E, Neumann V, Richards RG, Gueorguiev B, Gill H, Whitehouse M, Preatoni E, Fletcher J. 2019 Influence of different Lisfranc ligament injuries on CT Findings – A human cadaver study.
2019 EFORT (poster)Penev P, Qawasmi F, Mosheiff R, Knobe M, Krause F, Richards RG, Gueorguiev B, Klos K. 2019 Bone mass along pedicle screw S1 depends on the correct pathway: The Superior Articular Process Screw is a valuable alternative.
2019 EFORT (poster)Wagner D, Kamer L, Noser H, Rommens PM. 2019 SystemFix – Using computer simulations to optimise proximal humeral fracture fixation.
2019 ICORSFletcher J, Windolf M, Gueorguiev B, Richards RG, Varga P. 2019 Does supplemental dorsal plating increase stability of distal radius fractures after volar plating?
2019 ICORSHadzhinikolova M, Zderic I, Ciric D, Enchev D, Baltov A, Rusimov L, Richards RG, Rashkov M, Gueorguiev B. 2019 The effects of different insertion variables on achieved screw tightness.
2019 ICORSNeumann V, Wenzel L, Gueorguiev B, Richards RG, Gill H, Whitehouse M, Preatoni E, Fletcher J. 2019 Antibiotic-eluting scaffolds eliminate infection and facilitate bone tissue.
2019 ICORSSheehy EJ, von Diemling C, Moriarty TF, O'Brien FJ. 2019 Personalised bioactive implant made by stereolithography for orbital floor.
2019 ICORSEglin D. 2019 From wearables to smart implants: The AO Fracture Monitor to assess bone healing.
2019 ICORSGueorguiev B, Ernst M, Windolf M. 2019 Annulus fibrosus repair with endogenous cell activation and function inducing cell transplantation.
2019 ICORSLi Z. 2019 How to publish in eCM - a journal founded and run by scientists for the benefit of science rather than profit.
2019 ICORSStoddart M, Alini M. 2019 Evidence-based generic Asian pelvic bone models for research, development and teaching using CT-based 3D statistical modeling.
2019 ICORS (poster)Ahrend M-D, Noser H, Shanmugam R, Kamer L, Burr F, Hügli H, Zaman T, Richards RG, Gueorguiev B. 2019 Assessing screw tightness achieved by orthopaedic surgeons and researchers.
2019 ICORS (poster)Fletcher J, Wenzel L, Gueorguiev B, Richards RG, Gill H, Whitehouse M, Preatoni E. 2019 Does supplemental intramedullary grafting increase stability of plated proximal humerus fractures?
2019 ICORS (poster)Rusimov L, Zderic I, Ciric D, Barcik J, Enchev D, Rashkov M, Hadzhinikolova M, Richards RG, Baltov A, Gueorguiev B. 2019 Investigation into the prevention of BRONJ in the minipig large animal model – is there a role of drug holiday?
2019 ICORS (poster)Otto S, Pautke C, Arens D, Poxleitner P, Eberli U, Nehrbass D, Zeiter S, Stoddart MJ. 2019 3D statistisches Modell des Beckenrings – CT basierte Analyse interindividueller anatomischer Variabilität.
2019 VSOUArand C, Wagner D, Noser H, Kamer L, Richards RG, Sawaguchi T, Rommens PM. 2019 Anzahl möglicher trans-sakraler Implantate im Becken anhand virtueller Implantatpositionierung.
2019 VSOUNowak T, Wagner D, Kamer L, Noser H, Rommens PM. 2019 Die Länge und Knochenmasse der Pedikelschraube in S1 in Abhängigkeit des Verlaufes.
2019 VSOUWagner D, Kamer L, Noser H, Rommens PM. 2019 Boot W, Schmid T, Guillaume O, D'Este M, Foster A, Eglin D, Richards RG, Zeiter S, Moriarty TF. 2019 Thompson K, Burch M-A, Milstrey A, Eberli U, Arens D, Richards RG, Stadelmann VA, Moriarty TF. 2019 Puetzler J, Milstrey A, Everding J, Raschke M, Arens D, Zeiter S, Richards RG, Moriarty TF. 2019 Lee CC, Muthukrishnan G, Owen JR, Kates SL, Beck CA, Daiss JL, Post V, Moriarty TF, Zeiter S, Schwarz EM. 2019 Sheehy EJ, von Diemling C, Moriarty TF, O'Brien FJ. 2019 Burch M-A, Kühl R, Morgenstern M, Metsemakers W-J. 2019 Chen Y, Post V, Moriarty TF, Richards RG, Boot W. 2019 Harris LG, Mageiros L, Post V, Mack D, Rohde H, Moriarty TF, Wilkinson TS. 2019 Hofstee M, Riool M, Zaat SAJ, Richards RG, Moriarty TF. 2019 Rotman SG, Wang M, Yang S, Grijpma DW, Richards RG, Moriarty TF, Eglin D. 2019 Stadelmann VA, Thompson K, Eberli U, Arens D, Richards RG, Moriarty TF. 2019 The influence of microbial-derived metabolites on bone health.
2019 eCM (poster)Wallimann A, Thompson K, Stanic B, O'Mahony L, Akdis CA, Moriarty TF. 2019 Ciric D, Mischler D, Qawasmi F, Wenzel L, Windolf M, Gueorguiev B, Varga P. 2019 Ciric D, Mischler D, Qawasmi F, Windolf M, Gueorguiev B, Varga P. 2019 Escalante I, Zderic I, Schopper C, Richards RG, Gueorguiev B, Kfuri M. 2019 Mischler D, Windolf M, Varga P. 2019 Mys K, Varga P, Stockmans F, Gueorguiev B, Neumann V, Vanovermeire O, Wyers CE, van den Bergh JPW, van Lenthe GH. 2019 Penev P, Klos K, Qawasmi F, Mosheiff R, Knobe M, Krause F, Richards RG, Gueorguiev B. 2019 Silva-Henao J, Ovesy M, Fletcher JWA, Gueorguiev B, Zysset PK, Varga P. 2019 Yanev P, Zderic I, Pukalski Y, Enchev D, Rashkov M, Richards RG, Gueorguiev B, Baltov A. 2019 Breden S, Chamseddine M, Varga P, Müller PE, Pietschmann MF, Chevalier J. 2019 Barcik J, Ernst M, Freitag L, Dlaska C, Drenchev L, Gueorguiev B, Skulev H, Mys K, Epari D, Windolf M. 2019 Pukalski Y, Yanev P, Baltov A, Rashkov M, Schmidutz F, Zderic I, Sprecher C, Richards RG, Gueorguiev B, Enchev D. 2019 3D Printing of a Hyaluronan Bioink With Double Gelation Mechanism for Independent Tuning of Shear-Thinning and Shape Fixation.
2019 Royan SCBTPetta D, Grijpma DW, Alini M, Eglin D, D'Este M. 2019 Towards Clinical Translation: Patents and Intellectual Property in Biomaterials Science.
2019 Royan SCBTD'Este M. 2019 Validation of cell line models to study intervertebral disc neo-innervation associated with discogenic pain.
2019 Swiss 3Rs Day (poster)Ma J, Stefanoska D, Hildebrand M, Zeiter S, Alini M, Peroglio M. 2019 A Vancomycin and Gentamicin-Loaded Thermo-responsive Hydrogel Successfully Treats Chronic MRSA Implant-Associated Osteomyelitis in a Sheep Model.
2019 SGM – SSM (poster)Boot W, Zeiter S, D'Este M, Eglin D, Foster A, Schmid T, Guillaume O, Richards RG, Moriarty TF. 2019 The influence of microbial-derived metabolites on bone health.
2019 SGM – SSM (poster)Wallimann A, Thompson K, Stanic B, O'Mahony L, Akdis CA, Moriarty TF. 2019 Effect of pH and oxygen tension on dorsal root ganglion calcium response to bradykinin and neurite sprouting.
2019 Pain (poster)Ma J, Stefanoska D, Grad S, Alini M, Peroglio M. 2019 Effects of glucose concentration and pH on dorsal root ganglion neurite outgrowth.
2019 Pain (poster)Stefanoska D, Ma J, Grad S, Alini M, Peroglio M. 2019 Local antibiotics delivery with hydrogels: from infection prevention to infection eradication in orthpedic trauma.
2019 ESBioMatD'Este M, Moriarty TF. 2019 From bench science to clinical translation: patents in biomaterials.
2019 ESBioMatD'Este M. 2019 Microparticles with enhanced bone affinity for efficient antibiotic delivery to infected bone fractures.
2019 ESBioMatRotman S, Wang M, Yang S, Grijpma D, Richards RG, Eglin D, Moriarty TF, Tang TT, Guillaume O. 2019 Joint mimicking mechanical loading activates endogenous TGF- ß 1 in a cellularized bioadhesive hydrogel eligible for cartilage regeneration.
2019 AGA (poster)Behrendt P, Ladner Y, Lippross S, Alini M, Stoddart M, Eglin D, Armiento A. 2019 Influence of titanium elastic nail pre-contouring on the fixation of paediatric diaphyseal forearm fractures.
2019 Osteosynthese InternationalPukalski Y, Yanev P, Rashkov M, Schmidutz F, Zderic I, Sprecher C, Richards RG, Gueorguiev B, Baltov A, Enchev D. 2019 Development of tailor-made equipment for experimental preclinical surgeries using computer simulations and 3D printing.
2019 ICMCCBarcik J, Ernst M, Schwyn R, Freitag L, Dlaska C, Drenchev L, Todorov S, Gueorguiev B, Skulev H, Epari D, Windolf M. 2019 AO translational research and development.
2019 ICMCCGueorguiev B, Stoddart M, Zeiter S, Richards RG. 2019 Delamination of the Hydroxyapatite Coating from the Stem 14 Months after Total Hip Arthroplasty.
2019 IMORSchönweger F, Sprecher CM, Neels A, Dommann A, Meier C, Wahl P. 2019 Evidence-based generic Asian pelvic bone models for research, development and teaching using CT-based 3D statistical modeling.
2019 EORSAhrend M-D, Zderic I, Noser H, Shanmugam R, Kamer L, Burr F, Hügli H, Kamarul T, Richards RG, Gueorguiev B. 2019 Automated electromechanical system designed to investigate the effect of local mechanical conditions on fracture healing progression.
2019 EORSBarcik J, Ernst M, Freitag L, Dlaska C, Drenchev L, Todorov D, Gueorguiev B, Skulev H, Zeiter S, Epari D, Windolf M. 2019 Continuous monitoring of fracture healing to analyze short-term response of bone repair tissue to mechanical stimulation.
2019 EORSBarcik J, Ernst M, Balligand M, Dlaska C, Drenchev L, Todorov D, Gueorguiev B, Skulev H, Zeiter S, Epari D, Windolf M. 2019 Local non-viral gene delivery to immunomodulate and enhance fracture healing.
2019 EORSGomez-Sierra MA, Lackington WA, Alini M, Thompson K. 2019 Biphasic Plating – In vivo study on a novel fixation concept to enhance mechanobiological fracture healing.
2019 EORS (oral)Hofmann-Fliri L, Epari D, Schwyn R, Zeiter S, Windolf M. 2019 A novel 3-dimensional in vitro model for osteomyelitis associated staphylococcal abscess communities.
2019 EORSHofstee M, Riool M, Thompson K, Stoddart MJ, Zaat SAJ, Moriarty TF. 2019 Externalized locked plating of unstable proximal tibia fractures can provide sufficient stability under partial weightbearing – a finite element study.
2019 EORSMakelov B, Zderic I, Silva JD, Apivatthakakul T, Gueorguiev B, Varga P. 2019 Improving fixation techniques of proximal humerus fractures by means of finite element analysis.
2019 EORSMischler D, Schader J, Windolf M, Varga P. 2019 Influence of different Lisfranc ligament injuries on CT findings.
2019 EORSPenev P, Zderic I, Qawasmi F, Mosheiff R, Knobe M, Krause F, Richards RG, Raykov D, Gueorguiev B, Klos K. 2019 Better Stability and More Predictive Fixation of the Femoral Neck System versus Two Hansson Pins in Pauwels II Femoral Neck Fractures – A Biomechanical Study.
2019 EORSSchopper C, Zderic I, Menze J, Müller D, Rocci M, Knobe M, Shoda E, Richards RG, Gue B. 2019 Impact of titanium elastic nail pre-contouring on the fixation of paediatric diaphyseal forearm fractures.
2019 EORS (poster)Pukalski Y, Yanev P, Rashkov M, Schmidutz F, Zderic I, Sprecher C, Richards RG, Gueorguiev B, Baltov A, Enchev D. 2019 Is double plating of displaced midshaft clavicle fractures advantageous over single plate fixation?
2019 EORS (poster)Yanev P, Pukalski Y, Zderic I, Rashkov M, Richards RG, Gueorguiev B, Enchev D, Baltov A. 2019 AO preclinical research and development.
2019 BOTAGueorguiev B, Stoddart M, Zeiter S, Richards RG. 2019 Does supplemental dorsal locked plating increase stability of complex distal radius fractures after volar locked plating?
2019 BOTAHadzhinikolova M, Zderic I, Ciric D, Barcik J, Enchev D, Rusimov L, Richards RG, Gueorguiev B, Baltov A, Rashkov M. 2019 Ligamentous Lisfranc injury – analysis of CT findings under weightbearing
2019 BOTAPenev P, Klos K, Qawasmi F, Mosheiff R, Knobe M, Krause F, Richards RG, Gueorguiev B. 2019 Impact of titanium elastic nail prebending in the treatment of AO PCCF 22D/4.1 pediatric forearm fractures.
2019 BOTAPukalski Y, Yanev P, Rashkov M, Schmidutz F, Zderic I, Sprecher C, Richards RG, Gueorguiev B, Baltov A, Enchev D. 2019 Unstable proximal humerus fractures: Benefits of using intramedullary graft in locked plate fixation.
2019 BOTARusimov L, Zderic I, Ciric D, Barcik J, Rashkov M, Hadzhinikolova M, Richards RG, Gueorguiev B, Enchev D, Baltov A. 2019 Two reconstruction plates provide superior stability of displaced midshaft clavicle fractures in comparison to single plating.
2019 BOTAYanev P, Zderic I, Pukalski Y, Rashkov M, Richards RG, Gueorguiev B, Enchev D, Baltov A. 2019 External one-staged locked plating of unstable proximal tibia fractures can provide callus formation and sufficient stability under partial weightbearing. A finite element study.
2019 BOTA (poster)Makelov B, Silva JD, Apivatthakakul T, Gueorguiev B, Varga P. 2019 Analysis of the short-term response of fracture repair tissue to mechanical stimulation.
2019 TERMIS AP (poster)Barcik J, Ernst M, Balligand M, Dlaska CE, Drenchev L, Todorov D, Skulev H, Zeiter S, Epari D, Windolf M. 2019 Automated active fixation system designed to investigate the influence of local mechanical environment on fracture healing.
2019 TERMIS AP (poster)Barcik J, Ernst M, Freitag L, Dlaska C, Drenchev L, Todorov D, Skulev H, Zeiter S, Epari D, Windolf M. 2019 Optimising proximal humerus fracture plating – discoveries from computer simulations.
2019 LSM (poster)Fletcher J, Windolf M, Richards RG, Gueorguiev B, Varga P. 2019 TightRight: augmenting screwdrivers to reduce bone stripping rates and optimise tightness when inserting non-locking screws.
2019 BRS & BORSFletcher J, Neumann V, Silva J, Mys K, Panagiotopoulou V, Verschueren A, Gueorguiev B,
Richards RG, Whitehouse M, Preatoni E, Gill H.2019 What is the optimum tightness for non-locking cortical screws, and how can this be predicted prior to insertion?
2019 BRS & BORS (poster)Fletcher J, Zderic I, Gueorguiev B, Richards RG, Gill H, Whitehouse M, Preatoni E. 2019 Augmented screwdrivers greatly reduce bone stripping rates and optimise tightness when used to insert non-locking screws.
2019 BOA (poster)Fletcher J, Neumann V, Silva J, Mys K, Panagiotopoulou V, Gueorguiev B, Richards RG,
Whitehouse M, Preatoni E, Gill H.2019 Percutane retrograde transpubische Schraubenosteosynthese - anatomische Analyse des Schraubenkorridors basierend auf einem 3D statistischen Modell des Beckenrings.
2019 DKOU (oral)Arand C, Wagner D, Noser H, Kamer L, Gehweiler D, Richards RG, Rommens P. 2019 Silber-beschichtete winkelstabile Platten zeigen ungestörte Frakturheilung und gute Biokompatibilität im Kaninchenmodell.
2019 DKOU (oral)Arens D, Zeiter S, Ranjan N, Paulin T, Alt V. 2019 One-way Street Disc Degeneration? An Investigation of Hydrogel and Fibroblast Growth Factor 18 (FGF-18) for Intervertebral Disc Regeneration.
2019 DKOU (oral)Häckel S, Li Z, Zolfaghar M, Yayon A, Hoppe S, Benneker L, Alini M, Grad S. 2019 Präoperatives klinisches Scoring als prädiktiver Faktor für die Überlebensrate nach valgisierender open wedge HTO.
2019 DKOU (oral)Klink J, Ihle C, Ateschrang A, Gueorguiev B, Stöckle U, Schreiner AJ, Schröter S. 2019 Mikrozirkulation bei der intraartikulären Kalkaneusfraktur: Können wir Wundheilungsstörungen vorhersagen?
2019 DKOU (oral)Knobe M, Link B, Beeres F, Gueorguiev B, Modabber A, Horst K, Lichte P, Klos K. 2019 Fokussierte hochenergetische Stosswellentherapie (fhESWT) reduziert Staph. aureus Biofilm in vitro.
2019 DKOU (oral)Milstrey A, Pützler J, Everding J, Richards RG, Moriarty TF, Raschke M. 2019 Biomechanical investigation of the effect of screw length on screw perforation in unstable 3-part osteoporotic proximal humerus fractures.
2019 DKOU (oral)Wenzel L, Ciric D, Mischler D, Qawasmi F, Gueorguiev B, Richards RG, Windolf M, Varga P. 2019 Biomechanical evaluation of three different plating techniques for fixation of displaced midshaft clavicle factures.
2019 DKOU (oral)Zderic I, Yanev P, Pukalski Y, Enchev D, Rashkov M, Richards RG, Gueorguiev B, Baltov A. 2019 Fokussierte hochenergetische Stosswellentherapie (fhESWT) führt nicht zu septischer Streuung bei florider Infektion im Kaninchen Frakturmodell.
2019 DKOU (poster)Milstrey A, Pützler J, Everding J, Arens D, Zeiter S, Richards RG, Moriarty TF, Raschke M. 2019 Annulus fibrosus differentiation of human bone marrow stem cells on polycaprolactone scaffolds with 3D printed oriented ply structure.
2019 ORS PSRS (oral)Vernengo A, Li Z, Grad S, Alini M, Eglin D. 2019 Harmonization and Standardization of Intervertebral Disc Cell Culture Methods
2019 ORS PSRS (oral)Binch ALA, Basatvat S, Owen D, Snuggs J, Richardson S, Hoyland JA, Gansau J, Buckley CT, Glaeser JD, Sheyn D, Wang D, Vo N, Jacobsen T, Chahine NO, Presciutti SM, Drissi H,
Yoon T, Gawri R, Lang G, Hernandez PA, Fearing BV, Setton LA, Gullbrand SE, Dudli S,
Schol J, Sakai D, Guerrero J, Gantenbein B, Li Z, Peroglio M, Alini M, Grad S, Kraus P,
Lufkin T, O'Donnell GD, Dahia C, Takashi K, Kushioka J, Wachs RA, DiStefano T,
Panebiancho C, Illien-Junger S, Iatridis JC, Bowles RD, Sun Y, Leung VY, Haglund L,
Mizuno S, Huang C-Y, Alvarez-Garcia O, Silverman L, Li X, Garcia JP, Creemers LB, Ito K, Bach F, Tryfonidou M, LeMaitre CL.2019 Locally delivered mesenchymal stem cell homing enables intervertebral disc repair: A proof-of-concept study.
2019 ORS PSRS (oral)Schol J, Sakai D, Warita T, Peroglio M, Li Z, Zeiter S, Grad S, Alini M. 2019 Functional cell phenotype induction with TGFß1 and collagen-polyurethane scaffold for annulus fibrosus repair.
2019 ORS PSRS (poster)Li Z, Du J, Long RG, Sakai D, Benneker LM, Iatridis JC, Alini M, Grad S. 2019 Pre-clinical testing of anti-inflammatory and regenerative drug therapy in a bioreactor-guided intervertebral disc organ culture model.
2019 ORS PSRS (poster)Li Z, Gehlen Y, Heizmann F, Kubosch D, Südkamp N, Alini M, Grad S, Lang G. 2019 Hypoxia and low pH stressed disc conditioned medium promotes hypersensitivity of peripheral sensory neurons.
2019 ORS PSRS (poster)Ma J, Stefanoska D, Grad S, Alini M, Peroglio M. 2019 Fibrin-hyaluronic acid hydrogel and Fibroblast Growth Factor-18 for Intervertebral Disc Regeneration: an in vitro study on bovine and human nucleus pulposus cells.
2019 ORS PSRS (poster)Häckel S, Zolfaghar M, Du J, Hoppe S, Benneker LM, Peroglio M, Alini M, Grad S, Yayon A, Li Z. 2019 Stem Cells without the hype: What is the real science?
2019 ICRS (oral)Stoddart MJ. 2019 ¿Es la inserción de tornillos con 2 dedos más segura?
2019 SECOT (poster)Jorge Mora A, Keltz E, Fletcher J, Gueorguiev B, Cabrillo Estévez C, Viana Giorno C. 2019 A sound-induced technology for multiscale orchestration of functional vessels networks.
2019 ATSM (poster)Serra T. 2019 Smart surgery – translational research and development at the AO Research Institute Davos.
2019 HSS Exp Surg (oral)Varga P, Gueorguiev B, Richards RG, Windolf M. 2019 Local delivery of IL-1Ra as a strategy to enhance long bone healing.
2019 SBMS (oral)Lackington W, Hildebrand M, Alini M, Zeiter S, Thompson K. 2019 Local non-viral gene delivery to immunomodulate and enhance fracture healing.
2019 SBMS (oral)Gomez-Sierra MA, Lackington WA, Alini M, Thompson K. 2019 Calcium polyphosphate-nanoparticles act as an effective inorganic phosphate source during the in vitro osteogenic differentiation of human bone marrow-derived MSCs.
2019 SBMS (oral)Hatt LP, Thompson K, Müller WEG, Stoddart MJ, Armiento AR. 2019 Joint mimicking mechanical load activates endogenous TGF-β in a highly cellularized bioadhesive hydrogel for cartilage repair.
2019 SBMS (oral)Behrendt P, Ladner Y, Stoddart MJ, Lippross S, Alini M, Eglin D, Armiento AR. -
Peer-reviewed publications
2019 Chasing Chimeras – The elusive stable chondrogenic phenotype.
Biomaterials. 2019;192:199-225(epub 2018; Nov 9)Graceffa V, Vinatier C, Guicheux J, Stoddart M, Alini M, Zeugolis DI. 2019 Biomechanical properties of plate constructs for feline ilial fracture gap stabilization.
Vet Surg. 2019;48(1):88-95(epub 2018; Nov 13)Schmierer PA, Smolders LA, Zderic I, Gueorguiev B, Pozzi A, Knell SC. 2019 3D statistical model of the pelvic ring - a CT-based statistical evaluation of anatomical variation.
J Anat. 2019;234(3):376-83(epub 2018; Dec 21)Arand C, Wagner D, Richards RG, Noser H, Kamer L, Sawaguchi T, Rommens PM. 2019 General Assembly, Prevention, Local Antimicrobials: Proceedings of International Consensus on Orthopedic Infections.
J Arthroplasty. 2019;34(2 Suppl):S75-S84 (epub 2018;Oct 20)Baeza J, Cury MB, Fleischman A, Ferrando A, Fuertes M, Goswami K, Lidgre L, Linke P, Manrique J, Makar G, McLaren A, Moriarty TF, Ren Q, Vince K, Wahl P, Webb J, Winkler H, Witso E, Young SW. 2019 Osteogenic magnesium incorporated into PLGA/TCP porous scaffold by 3D printing for repairing challenging bone defect.
Biomaterials. 2019;197:207-19Lai Y, Li Y, Cao H, Long J, Wang X, Li L, Li C, Jia Q, Teng B, Tang T, Peng J, Eglin D, Alini M, Grijpma DW, Richards RG, Qin L. 2019 Ihle C, Maurer J, Ziegler P, Stöckle U, Ateschrang A, Ahrend MD, Schröter S. 2019 A Stimuli-Responsive Nanocomposite for 3D Anisotropic Cell-Guidance and Magnetic Soft Robotics.
Adv Funct Mater. 2019;29(9):10(epub 2018; Dec 18)Tognato R, Armiento AR, Bonfrate V, Levato R, Malda J, Alini M, Eglin D, Giancane G, Serra T. 2019 Clinical application of a minimally invasive cement-augmentable Schanz screw rod system to treat pelvic ring fractures.
Int Orthop. 2019;43(3):697-703(epub 2018; May 21)Schmitz P, Baumann F, Acklin YP, Gueorguiev B, Nerlich M, Grechenig S, Müller MB. 2019 Improved results of ACL primary repair in one-part tears with intact synovial coverage.
Knee Surg Sports Traumatol Arthrosc. 2019;27(1):37-43 (epub 2018; Oct 8)Ateschrang A, Schreiner AJ, Ahmad SS, Schröter S, Hirschmann MT, Körner D, Kohl S, Stöckle U, Ahrend MD. 2019 Is bone-cement augmentation of screw-anchor fixation systems superior in unstable femoral neck fractures? A biomechanical cadaveric study.
Injury. 2019;50(2):292-300(epub 2018; Oct 30)Knobe M, Bettag S, Kammerlander C, Altgassen S, Maier KJ, Nebelung S, Prescher A, Horst K, Pishnamaz M, Herren C, Mundt M, Stoffel M, Markert B, Gueorguiev B. 2019 The importance of locking plate positioning in proximal humeral fractures as predicted by computer simulations.
J Orthop Res. 2019;epub Jan 28Fletcher JWA, Windolf M, Richards RG, Gueorguiev B, Buschbaum J, Varga P. 2019 Kurutz M, Varga P, Jakab G. 2019 Shear and Dynamic Compression Modulates the Inflammatory Phenotype of Human Monocytes in vitro.
Front Immunol. 2019;10(383)Fahy N, Menzel U, Alini M, Stoddart MJ. 2019 Thompson K, Petkov S, Zeiter S, Sprecher CM, Richards RG, Moriarty TF, Eijer H. 2019 Recommendations for design and conduct of preclinical in vivo studies of orthopedic device-related infection.
J Orthop Res. 2019;37(2):271-87Moriarty TF, Harris LG, Mooney RA, Wenke JC, Riool M, Zaat SAJ, Moter A, Schaer TP, Khanna N, Kuehl R, Alt V, Montali A, Liu J, Zeiter S, Busscher HJ, Grainger DW, Richards RG. 2019 Busscher HJ, Alt V, van der Mei HC, Fagette PH, Zimmerli W, Moriarty TF, Parvizi J, Schmidmaier G, Raschke MJ, Gehrke T, Bayston R, Baddour LM, Winterton LC, Darouiche RO, Grainger DW. 2019 Long-term outcome after surgical treatment of intra-articular tibial plateau fractures in skiers.
Arch Orthop Trauma Surg. 2019;139:951-59Bäumlein M, Hanke A, Gueorguiev B, Nerlich M, Liodakis E, Perren T, Rillmann P, Ryf C, Loibl M. 2019 The influence of screw length on predicted cut-out failures for proximal humeral fracture fixations predicted by finite element simulations.
Arch Orthop Trauma Surg. 2019;139:1069-1074Fletcher JWA, Windolf M, Grünwald L, Richards RG, Gueorguiev B, Varga P. 2019 Does Riluzole Influence Bone Formation? An in vitro Study of Human Mesenchymal Stromal Cells and Osteoblast.
Spine (Phila Pa 1976). 2019;44:1107-1117Schroeder GD, Kepler CK, Grad S, Alini M, Fang T, Markova DZ, Koerner JD, Rajasekaran S, Chapman J, Kandziora F, Schnake KJ, Dvorak MF, Oner FC, Vaccaro AR. 2019 Ganse B, Böhle F, Pastor T, Gueorguiev B, Altgassen S, Gradl G, Kim B-S, Modabber A, Nebelung S, Hildebrand F, Knobe M. 2019 Computerized anatomy of the distal radius and its relevance to volar plating, research, and teaching.
Clin Anat. 2019;32(3):361-8
(epub 2018; Dec 23)Gehweiler D, Teunis T, Varjas V, Kerstan D, Gueorguiev B, Kamer L, Noser H. 2019 Does Supplemental Intramedullary Grafting Increase Stability of Plated Proximal Humerus Fractures?
J Orthop Trauma. 2019;33(4):196-202
(epub 2018; Dec 13)Rusimov L, Zderic I, Ciric D, Barcik JP, Enchev D, Rashkov M, Hadzhinikolova M, Richards RG, Gueorguiev B, Baltov A. 2019 Prevalence and quantification of contamination of knitted cotton outer gloves during hip and knee arthroplasty surgery.
Arch Orthop Trauma Surg. 2019;139(4):
451-9(epub 2018; Nov 7)Wichmann T, Moriarty TF, Keller I, Pfister S, Deggim-Messmer V, Gautier E, Kalberer F, Koch PP, Wahl P. 2019 Infection burden and immunological responses are equivalent for polymeric and metallic implant materials in vitro and in a murine model of fracture-related infection.
J Biomed Mater Res B Appl Biomater. 2019;107(4):1095-106
(epub 2018; Oct 17)Rochford ETJ, Sabate Bresco M, Poulsson AHC, Kluge K, Zeiter S, Ziegler M, O'Mahony L, Richards RG, Moriarty TF. 2019 Influence of reduced tip-apex distance on helical blade fixation-a biomechanical study.
J Orthop Res. 2019;37(3):649-54(epub 2018; Dec 13)Lenz M, Schwinn J, Hofmann-Fliri L, Schwyn R, Knobe M, Klos K, Kielstein H, Hofmann GO, Gueorguiev B. 2019 Relative effects of age on implant integration in a rat model: A longitudinal in vivo microct study.
J Orthop Res. 2019;37(3):541-52(epub 2018; Dec 21)Freitag L, Günther C, Eberli U, Fürst A, Zeiter S, Stadelmann VA. 2019 Introduction of the Anspach drill as a novel surgical driller for creating calvarial defects in animal models.
J Orthop Res. 2019;37:1183-91Guillaume O, Schmid T, Kluge K, Weber FE, Richards RG, Eberli U, Eglin D, Zeiter S. 2019 Medication-related osteonecrosis of the jaw in a minipig model: Parameters for developing a macroscopic, radiological, and microscopic grading scheme.
J Craniomaxillofac Surg. 2019;47:1162-1169Nowicki B, Nehrbass D, Arens D, Stadelmann VA, Zeiter S, Otto S, Kircher P, Stoddart MJ. 2019 Mys K, Varga P, Gueorguiev B, Hemmatian H, Stockmans F, van Lenthe GH. 2019 Human Umbilical Cord-derived Scaffolds for Cartilage Tissue Engineering.
J Biomed Mater Res A. 2019;
107:1793-1802Safari F, Fani N, Eglin D, Alini M, Stoddart MJ, Eslaminejad M.B. 2019 CD146/MCAM distinguishes stem cell subpopulations with distinct migration and regenerative potential in degenerative intervertebral discs.
Osteoarthritis Cartilage. 2019;27:1094-1105Wangler S, Menzel U, Li Z, Ma J, Hoppe S, Benneker LM, Alini M, Grad S, Peroglio M. 2019 Effect and mechanism of psoralidin on promoting osteogenesis and inhibiting adipogenesis.
Phytomedicine. 2019;61:152860Cao HJ, Li CR, Wang LY, Ziadlou R, Grad S, Zhang Y, Cheng Y, Lai YX, Yao XS, Alini M, Qin L, Wang XL. 2019 Puetzler J, Zalavras C, Moriarty TF, Verhofstad MHJ, Kates SL, Raschke MJ, Rosslenbroich S, Metsemakers WJ. 2019 Screw configuration in proximal humerus plating has a significant impact on fixation failure risk predicted by finite element models.
J Shoulder Elbow Surg. 2019;28:1816-23Fletcher JWA, Windolf M, Richards RG, Gueorguiev B, Varga P. 2019 Space available for trans-sacral implants to treat fractures of the pelvis assessed by virtual implant positioning.
Arch Orthop Trauma Surg. 2019;139(10):1385-91Wagner D, Kamer L, Sawaguchi T, Noser H, Uesugi M, Baranowski A, Gruszka D, Rommens PM. 2019 Ventral Surgical Approach for an Intervertebral Disc Degeneration and Regeneration Model in Sheep Cervical Spine: Anatomic Technical Description, Strengths and Limitations.
Vet Comp Orthop Traumatol. 2019;32(5):389-393Deml MC, Benneker LM, Schmid T, Sakai D, Albers CE, Hoppe S, Zeiter S. 2019 FACS is more potent to fish IVD progenitor cells than magnetic and bead-based methods.
Tissue Eng Part C Methods. 2019;25(10):571-580Frauchiger DA, Tekari A, May RD, Dzafo E, Chan SC, Stoyanov J, Bertolo A, Zhang X, Guerrero J, Sakai D, Schol J, Grad S, Tryfonidou MA, Benneker LM, Gantenbein B. 2019 Kovermann NJ, Basoli V, Della Bella E, Alini M, Lischer C, Schmal H, Kubosch EJ, Stoddart MJ. 2019 Undergraduate Curricular Training in Musculoskeletal Ultrasound by Student Teachers: The Impact of Peyton's Four-Step Approach.
Z Orthop Unfall. 2019;157(3):270-8 (epub 2018; Oct 12)Gradl-Dietsch G, Hitpass L, Gueorguiev B, Nebelung S, Schrading S, Knobe M. 2019 Regenerative rehabilitation: The role of mechanotransduction in orthopaedic regenerative medicine.
J Orthop Res. 2019;37(6):1263-9 (epub 2018;Dec 17)Glatt V, Evans CH, Stoddart MJ. 2019 Gieling F, Peters S, Erichsen C, Richards RG, Zeiter S, Moriarty TF. 2019 Hagen JE, Rausch S, Simons P, Richards RG, Lenz M, Knobe M, Gueorguiev B, Klos K. 2019 In vitro simulation of the early proinflammatory phase in fracture healing reveals strong immunomodulatory effects of CD146-positive mesenchymal stromal cells.
J Tissue Eng Regen Med. 2019;13:1466-81Herrmann M, Stanic B, Hildebrand M, Alini M, Verrier S. 2019 Herrmann M, Hildebrand M, Menzel U, Fahy N, Alini M, Lang S, Benneker L, Verrier S, Stoddart MJ, Bara JJ. 2019 Wangler S, Peroglio M, Menzel U, Benneker LM, Haglund L, Sakai D, Alini M, Grad S. 2019 Hydrogel-based delivery of antimiR-221 enhances cartilage regeneration by endogenous cells.
J Control Release. 2019;309:220-30Lolli A, Sivasubramaniyan K, Vainieri ML, Oieni J, Kops N, Yayon A, van Osch G.J.V.M. 2019 Zderic I, Willhuber GC, Ahrend M-D, Gras F, Barla J, Sancineto C, Windolf M, Richards RG, Gueorguiev B. 2019 Xu Y, Peng J, Richards RG, Lu S, Eglin D. 2019 Ciric D, Mischler D, Qawasmi F, Wenzel L, Richards RG, Gueorguiev B, Windolf M, Varga P. 2019 Targeted Cell Delivery for Articular Cartilage Regeneration and Osteoarthritis Treatment.
Drug Discov Today. 2019;24(11):2212-2224Nasiri N, Hosseini S, Alini M, Khademhosseini A, Eslaminejad MB. 2019 Development of a novel murine delayed secondary fracture healing in vivo model using periosteal cauterization.
Arch Orthop Trauma Surg. 2019;139(12):1743-1753Gröngröft I, Wissing S, Meesters DM, Poeze M, Matthys-Mark R, Ito K, Zeiter S. 2019 Editorial: Functionalization at Nanoscale to Enhance Specific Biological Activities.
Front Bioeng Biotechnol. 2019;7:178Gentile P, Alarcon EI, Alini M. 2019 Multi-Disciplinary Approaches for Cell-Based Cartilage Regeneration.
J Orthop Res. 2019;epub Sep 3Johnstone B, Stoddart MJ, Im GI. 2019 Interaction of gentamicin sulfate with alginate and consequences on the physico-chemical properties of alginate-containing biofilms.
Int J Biol Macromol. 2019;121:390-7 (epub 2018, Oct 7)Heriot M, Nottelet B, Garric X, D'Este M, Richards GR, Moriarty FT, Eglin D, Guillaume O. 2019 Decellularized matrix as a building block in bioprinting and electrospinning.
Curr Opin Biomed Eng. 2019;10:116-22Santschi M, Vernengo A, Eglin D, D'Este M, Wuertz-Kozak K. 2019 Electrospray-Based Microencapsulation of Epigallocatechin 3-Gallate for Local Delivery into the Intervertebral Disc.
Pharmaceutics. 2019;11(9):e435Loepfe M, Duss A, Zafeiropoulou KA, Bjorgvinsdottir O, D'Este M, Eglin D, Fortunato G, Klasen J, Ferguson SJ, Wuertz-Kozak K, Krupkova O. 2019 Mechanochemical Adhesion and Plasticity in Multifiber Hydrogel Networks.
Advanced Materials. 2019;epub Dec 18( ):e:1905719Davidson MD, Ban E, Schoonen ACM, Lee M-H, D'Este M, Shenoy VB, Burdick JA. 2019 A Multifunctional Nanocomposite Hydrogel for Endoscopic Tracking and Manipulation. Advanced Intelligent Systems. 2019;epub Dec 03
Augurio A, Cortelletti P, Tognato R, Rios A, Levato R, Malda J, Alini M, Eglin D, Giancane G, Speghini A, Serra T. 2019 Morphological and biomechanical effects of annulus fibrosus injury and repair in an ovine cervical model.
JOR SPINE. 2019;epub Dec 21Long RG, Ferguson SJ, Benneker LM, Sakai D, Li Z, Pandit A, Grijpma DW, Eglin D, Zeiter S, Schmid T, Eberli U, Nehrbass D, Di Pauli von Treuheim T, Alini M, Iatridis JC, Grad S. 2019 Definitive external plate stabilization with metaphyseal locking plate LISS-DF in multiple trauma patient with "floating knee" injury. A case report
Ortopediâ i travmatologiâ / Bul J Ortop Trauma. 2019;56(1):12-19Makelov B, Gueorguiev B, Apivatthakakul T. 2019 Cell detachment rapidly induces changes in noncoding RNA expression in human mesenchymal stromal cells.
BioTechniques. 2019;67(6):286-93Della Bella E, Stoddart MJ. 2019 Impact of surgical procedures on soft tissue microcirculation in calcaneal fractures: A prospective longitudinal cohort study.
Injury. 2019;50(12):2332-2338Bläsius FM, Link BC, Beeres FJP, Iselin LD, Leu BM, Gueorguiev B, Klos K, Ganse B, Nebelung S, Modabber A, Eschbach D, Weber CD, Horst K, Knobe M. 2019 Reply Letter to the Editor: Clinical in Vivo Assessment of Bone Microarchitecture With CT Scanners: An Enduring Challenge.
J Bone Miner Res. 2019;epub Dec 5Mys K, Varga P, Gueorguiev B, Hemmatian H, Stockmans F, van Lenthe GH. 2019 Externalized locked plating of unstable high energy proximal tibial fractures. A fea study.
Ortopediâ i travmatologiâ / Bul J Ortop Trauma. 2019;56(3):124-38Makelov B, Silva JD, Apivatthakakul T, Gueorguiev B, Varga P. 2019 Humoral factors from musculoskeletal polytrauma patients impair antibacterial responses of neutrophils in vitro.
J Bone Jt Infect. 2019;4(6):280-4Stylianaki A, Stanic B, Morgenstern M, Richards RG, Moriarty TF, Thompson K. 2019 Focused high-energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture related infection.
J Orthop Res. 2019;epub Dec 11Puetzler J, Milstrey A, Everding J, Raschke M, Arens D, Zeiter S, Richards RG, Moriarty TF. 2019 Local application of a gentamicin-loaded hydrogel early after injury is superior to peri-operative systemic prophylaxis in a rabbit open fracture model.
J Orthop Trauma. 2019;epub Dec 6Vallejo A, Deimling C, Morgenstern M, D'Este M, Puetzler J, Zeiter S, Arens D, Metsemakers WJ, Richards RG, Eglin D, Moriarty TF. 2019 Evaluation of preclinical models for the testing of bone tissue engineered constructs.
Tissue Eng Part C Methods. 2019;epub Dec 6Zeiter S, Koschitzki K, Alini M, Jakob F, Rudert M, Herrmann M. 2019 An ex vivo bone defect model to evaluate bone substitutes and associated bone regeneration processes.
Tissue Eng Part C Methods. 2019;epub Dec 5Klüter T, Hassan R, Rasch A, Naujokat H, Wang F, Behrendt P, Lippross S, Gerdesmeyer L, Eglin D, Seekamp A, Fuchs S. 2019 Nachweis von Cutibacterium in der Schulterchirurgie.
Trauma und Berufskrankheit. 2019;21:217-222Schader JF, Hudek R, Trampuz A, Scheibel M. 2019 The Effect of Zoledronic Acid on Serum Biomarkers among Patients with Chronic Low Back Pain and Modic Changes in Lumbar Magnetic Resonance Imaging.
Diagnostics. 2019;9(4):212Koivisto K, Karppinen J, Haapea M, Järvinen J, Kyllönen E, Tervonen O, Niinimäki J, Alini M, Lotz J, Dudli S, Samartzis D, Risteli J, Majuri M-L, Alenius H, Grad S. 2019 Development of generic Asian pelvic bone models using CT-based 3D statistical modelling.
J Orthop Translat. 2019;epub Nov 4Ahrend M-D, Noser H, Shanmugam R, Burr F, Kamer L, Zaman TK, Hügli H, Nagy A, Richards RG, Gueorguiev-Rüegg B. 2019 Efficacy of antimicrobial agents delivered to hernia meshes using an adaptable thermo-responsive hyaluronic acid-based coating.
Hernia. 2019;epub Nov 28Pérez-Köhler B, Linardi F, Pascual G, Bellon JM, Eglin D, Guillaume O. 2019 Evaluation of biomimetic hyaluronic-based hydrogels with enhanced endogenous cell recruitment and cartilage matrix formation. Acta Biomater. 2019;epub Nov 11
Vainieri ML, Lolli A, Kops N, D'Atri D, Eglin D, Yayon A, Alini M, Grad S, Sivasubramaniyan K, van Osch GJVM. 2019 Regulation of inflammatory response in human osteoarthritic chondrocytes by novel herbal small molecules.
Int J Mol Sci. 2019;20(22):E5745Ziadlou R, Barbero A, Stoddart MJ, Wirth M, Li Z, Martin I, Wang XL, Qin L, Alini M, Grad S. 2019 Calcium Polyphosphate Nanoparticles Act as an Effective Inorganic Phosphate Source during Osteogenic Differentiation of Human Mesenchymal Stem Cells.
Int J Mol Sci. 2019;20(22):E5801Hatt LP, Thompson K, Müller WEG, Stoddart MJ, Armiento AR. 2019 Late screw-related complications in locking plating of proximal humerus fractures: A systematic review.
Injury. 2019;50(12):2176-2195Panagiotopoulou VC, Varga P, Richards RG, Gueorguiev B, Giannoudis PV. 2019 Pathogenesis and management of fracture-related infection. Clin Microbiol Infect.
2019; epub Aug 22Depypere M, Morgenstern M, Kuehl R, Senneville E, Moriarty TF, Obremskey WT, Zimmerli W, Trampuz A, Lagrou K, Metsemakers WJ. 2019 Evidence-based recommendations for Local antimicrobial strategies and Dead space management in Fracture-Related Infection.
J Orthop Trauma. 2019; epub Aug 26Metsemakers WJ, Fragomen AT, Moriarty TF, Morgenstern M, Egol KA, Zalavras C, Obremskey WT, Raschke M, McNally MA. 2019 General treatment principles for fracture-related infection: recommendations from an international expert group.
Arch Orthop Trauma Surg. 2019;epub Oct 29Metsemakers WJ, Morgenstern M, Senneville E, Borens O, Govaert GAM, Onsea J, Depypere M, Richards RG, Trampuz A, Verhofstad MHJ, Kates SL, Raschke M, McNally MA, Obremskey WT, Fracture-Related Infection Group. 2019 Kartogenin hydrolysis product 4-aminobiphenyl distributes to cartilage and mediates cartilage regeneration.
Theranostics. 2019;9(24):7108-21Zhang S, Hu P, Liu T, Li Z, Huang Y, Liao J, Hamid MR, Wen L, Wang T, Mo C, Alini M, Grad S, Wang T, Chen D, Zhou G. 2019 Fibrin-Hyaluronic Acid Hydrogel (RegenoGel) with Fibroblast Growth Factor-18 for In Vitro 3D Culture of Human and Bovine Nucleus Pulposus Cells.
Int J Mol Sci. 2019;20(20):5036Häckel S, Zolfaghar M, Du J, Hoppe S, Benneker LM, Garstka N, Peroglio M, Alini M, Grad S, Yayon A, Li Z. 2019 Intervertebral disc organ culture for the investigation of disc pathology and regeneration - benefits, limitations, and future directions of bioreactors.
Connect Tissue Res. 2019;epub Sep 26Pfannkuche JJ, Guo W, Cui S, Ma J, Lang G, Peroglio M, Richards RG, Alini M, Grad S, Li Z. 2019 Articular fibrocartilage - Why does hyaline cartilage fail to repair?
Adv Drug Deliv Rev. 2019;146:289-305Armiento AR, Alini M, Stoddart MJ. 2019
Comparison of x-ray and ct methods for assessing sacral shape variants and identifying a secure sacroiliac screw fixation corridor.
J Musculoskelet Res. 2019;22:1950007
Radetzki F, Goehre F, Schwan S, Wienke A, Jansch L, Ullrich B, Noser H, Wohlrab D, Delank K-S, Ludtka C, Mendel T.
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Theses and dissertations
2019 Cone-beam computed tomography is a fast and promising technique for microstructural imaging in clinical practice.
2019 KU Leuven (van Lenthe GH, Stockmans F, Varga P) – PhDMys K. 2019 Management of acute paediatric Monteggia fracture-dislocation.
2019 Medical University Sofia (Baltov A, Gueorguiev B) – PhDPukalski Y. 2019 Analysis of the outcomes after minimally invasive locked plating of distal femoral fractures AO 33A/33C.
2019 Medical University Sofia (Enchev D, Gueorguiev B) – PhDTodorov D. 2019 Investigation of fentanyl plasma levels after application of a fentanyl patch in three different locations in order to refine postoperative pain management in rabbits.
2019 Universität Bern (Spadavecchia C, Zeiter S) – DVMRiehl V. 2019 On Virtual Surgical Planning in Cranio-Maxillofacial Surgery.
Acta Universitatis Upsaliensis
2019 Uppsala University (Thor A, Kamer L) - PhDNilsson J. 2019 Experimental and computational investigation of the risk of overdrilling on the biomechanical competence of proximal humerus plating.
2019 ETH Zürich (Ferguson S, Varga P.) – MSc ETH BMEBurkhard B. 2019 The risk of secondary screw perforation in plate osteosynthesis of unstable proximal humerus fractures: prediction and the effect of screw length.
2019 Flinders University (Costi J, Varga P.) - MEngCiric D. 2019 Prediction of Interfragmentary Movement, Loading, and Implant Strain based on Finite Element Modelling and Strain Measurements with the AO Fracture Monitor.
2019 ETH Zürich (Ferguson JS, Ernst M, Mischler D) – MSc ETH BMEComtesse S. 2019 Synthesis and characterisation of double network tough hydrogels based on natural extracellular matrix components.
2019 ETH Zürich (Ferguson SJ, Eglin D, D'Este M) – MSc ETH HSTJucker TA. 2019 Secretome characterization of human mesenchymal stem cells stimulated with intervertebral disc conditioned medium – a proteomic based approach.
2019 ETH Zürich (Grad S, Würtz-Kozak K) - MSc ETHWapp C.
2018
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Abstracts published in journals
2018 Hyaluronan-based hydrogel delivering antimiR-221 for the guidance of endogenous cartilage repair.
Osteoarthritis Cartilage. 2018;26(Suppl 1):S163(2018 OARSI / poster)Lolli A, Sivasubramaniyan K, Vainieri ML, Eglin D, Wexselblatt E, Yayon A, Grad S, Alini M, van Osch GJ. 2018 Influence of polymeric adjuvants on the properties of Platelet Rich Plasma gel.
Osteologie. 2018;27(2):A55- (SVGO / SBMS)Arabpour Z, Keller J, Serra T, Alini M, Eglin D, Verrier S. 2018 Investigation of hydrogel and growth factors for intervertebral disc regeneration.
Osteologie. 2018;27(2):A55- (SVGO / SBMS)Haeckel S, Li Z, Yayon A, Hoppe S, Benneker L, Alini M, Grad S. 2018 Early prediction of healing outcome in a large bone defect rodent model via microCT.
Osteologie. 2018;27(2):A55- (SVGO / SBMS)Hildebrand M, Herrmann M, Gieling F, Gehweiler D, Verrier S, Alini M, Zeiter S, Thompson K. 2018 Chondrogenic culture media supplemented with high molecular weight hyaluronan to mimic healthy synovial fluid of the human knee joint.
Osteologie. 2018;27(2):A55- (SVGO / SBMS)Monaco G, Alini M, El Haj AJ, Stoddart MJ. 2018 Percutaneous retrograde transpubic screw fixation – a statistical analysis of availability, length of the screw corridor and local bone stock based on a 3D statistical model of the pelvic ring.
Eur J Trauma Emerg Surg. 2018;44(2 Suppl):S315 (ECTES)Arand C, Gehweiler D, Wagner D, Noser H, Kamer L, Richards RG, Sawaguchi T, Rommens PM. 2018 Bone mass and length depending on screw pathway in pedicle screw fixation in S1.
Eur J Trauma Emerg Surg. 2018;44(2 Suppl):S285-S286 (ECTES)Wagner D, Kamer L, Sawaguchi T, Noser H, Rommens P.M. 2018 A refined and clinically more relevant, preclinical osteochondral defect model in rabbits.
Vet Comp Orthop Traumatol. 2018;31(S 02): A13 (VOS 2018)Schmid T, Nehrbass D, Zeiter S. 2018 Validation of anti-inflammatory and anti-degenerative drug therapy using a bioreactor-guided intervertebral disc organ culture model.
Eur Spine J. 2018;27(Suppl 5 ):S679 (EuroSpine / poster)Heizmann F, Lang G, Liu Y, Geries J, Kubosch D, Südkamp N, Alini M, Grad S, Li Z. 2018 In vivo preclinical application of an active external fixator to investigate the influence of local mechanical conditions on the fracture healing.
Biomed Tech (Berl)2018;63(s1):s161(BMT)Barcik J, Ernst M, Freitag L, Dlaska CE, Gueorguiev B, Epari D, Windolf M. 2018 Personalised bioactive implant made by stereolithography for orbital floor fracture repair.
Bone Joint J. 2018;100-B(Suppl 14):132
2018 EORSEglin D, Geven M, Schmid T, Grijpma D, Bos RRM, Richards RG, Alini M, Guillaume O. 2018 Pre-clinical testing of biological therapies for the intervertebral disc using whole organ bioreactors.
Bone Joint J. 2018;100-B(Suppl 16):113
2018 EORSGrad S. 2018 Gueorguiev B. 2018 The design and preclinical evaluation of antibiotic releasing biomaterials.
Bone Joint J. 2018;100-B(Suppl 16):33
2018 EORSMoriarty TF. 2018 Stoddart M. 2018 Development of collagen/hyaluronic acid-tyramine (COLL/THA) composite hydrogels with tunable gelling kinetic and THA content for the treatment of nucleus pulposus.
Bone Joint J. 2018;100-B(Suppl 14):96
2018 EORSFrayssinet A, Petta D, Eglin D, D'Este M, Mosser G, Helary C. 2018 A hyaluronan-based hydrogel system for annulus fibrosus repair.
Bone Joint J. 2018;100-B(Suppl 16):119
2018 EORSGünay B, Isa ILM, Conrad C, Scarcelli G, Grad S, Li Z, Pandit A. 2018 The complex loosening mechanisms of pedicle screws in human vertebrae of reduced bone density under physiological gait simulation: an in vitro study.
Eur Spine J. 2018;27(11):2918-9 (DWK)Schulze M, Wähnert D, Riesenbeck O, Evers J, Raschke MJ, Vordemvenne T, Hartensuer R, Gehweiler D. 2018 Prediction of the material properties of vertebral body spongiosa using quantitative computer tomography.
Eur Spine J. 2018;27(11):2938 (DWK poster)Gehweiler D, Schulze M, Schultz M, Wähnert D, Müller M, Hartensuer R, Raschke MJ. 2018 Short- and mid-term effect of TNF-a intradiscal injection and detrimental dynamic loading in intervertebral disc organ culture.
Global Spine J. 2018;8(3 Suppl):27S-8S
(AOSpine Masters Symposium 2017)Li Z, Lang G, Liu Y, Geries J, Zhou Z, Kubosch D, Südkamp N, Alini M, Grad S. 2018 CD146 positive mesenchymal stem cell possess a superior migration potential both in vitro and in whole organ culture.
Global Spine J. 2018;8(3 Suppl):26S-7S
(AOSpine Masters Symposium 2017)Wangler S, Peroglio M, Li Z, Menzel U, Benneker LM, Richards RG, Alini M, Grad S. 2018 Nucleus Pulposus Progenitor Cells: Isolation and Injection Into Degenerative Disc.
Global Spine J. 2018;8(3 Suppl):7S-8S
(AOSpine Masters Symposium 2017)Frauchiger DA, Tekari A, Benneker LM, Sakai D, Grad S, Stoyanov J, Bertolo A, Gantenbein B. 2018 The effect of local antibiotic prophylaxis in open limb fractures: A systematic review and meta-analysis.
Bone Joint J. 2018;100-B(Suppl 17, Orthop Proc):89- (EBJIS / oral)Morgenstern M, Vallejo A, McNally D, Moriarty TF, Ferguson J, Nijs S, Metsemakers W. 2018 Current practices in the managment of open fractures: A worldwide survey among orthopaedic trauma surgeons.
Bone Joint J. 2018;100-B(Suppl 17, Orthop Proc):24- (EBJIS / oral)Pützler J, Zalavras C, Moriarty TF, Verhofstad MHJ, Kates S. -
Books and book chapters
2018 Biology and biomechanics in bone healing.
In: Buckley R, Moran C, Apivatthakakul T (Eds.) 2018.
AO Principles of Fracture Management.
Third Edition.
Davos, Stuttgart: AO Trauma / Thieme, p. 9-26Gueorguiev-Rüegg B, Stoddart M. 2018 Implants and biotechnoloy.
In: Buckley R, Moran C, Apivatthakakul T (Eds.) 2018.
AO Principles of Fracture Management.
Third Edition.
Davos, Stuttgart: AO Trauma / Thieme, p. 27-38Richards RG. 2018 Trauma: Principles of fractures.
Chapter 23, 44 pages.
In: Blom A, Warwick D, Whitehouse M (Eds.) 2018.
Apley & Solomon’s System of Orthopaedics and Trauma 10th Edition. Boca Raton: CRC PressGueorguiev B, Moriarty TF, Stoddart M, Acklin YP, Richards RG, Whitehouse MR. 2018 Developmental Biology and Musculoskeletal Tissue Engineering. Principles and Applications.
Boston: Academic Press / Elsevier; 2018Stoddart MJ, Craft AM, Pattappa G, Gardner OFW (Eds.) 2018 Intervertebral Disc Whole Organ Cultures: How to Choose the Appropriate Model.
In: R. Goncalves, M. Barbosa (Eds.)
2018. Gene and Cell Delivery for Intervertebral Disc Degeneration. Boca Raton: CRC PressWangler S, Li Z, Grad S, Peroglio M. -
Conference presentations
2018 Bony integration of porous tantalum despite ongoing infection: histologic workup of an explanted shoulder prosthesis.
2018 Endoprothetik (poster)Wahl P, Sprecher CM, Brüning C, Meier C, Gautier E, Moriarty TF. 2018 New insights into the interplay between Runx2 and protein Rb during fate commitment of mesenchymal stromal cells.
2018 ORS (poster)Armiento A, Alini M, Stoddart MJ. 2018 Early prediction of healing outcome in a large bone defect rodent model via microCT.
2018 ORS (poster)Hildebrand M, Herrmann M, Thompson K, Gieling F, Gehweiler D, Verrier S, Alini M, Zeiter S. 2018 Hyaluronan supplemented chondrogenic culture media to mimic synovial fluid behavior of the human knee joint.
2018 ORS (poster)Monaco G, Alini M, El Haj AJ, Stoddart MJ. 2018 Immunological and tomographic characterization of a large bone defect model in rats.
2018 ORS (poster)Thompson K, Hildebrand M, Zeiter S, Gieling F, Gehweiler D, Verrier S, Alini M, Herrmann M. 2018 Homing of mesenchymal stem cells enhances Tie2+ progenitor cells and induces a proliferative response in intervertebral disc organ culture.
2018 ORS (poster)Wangler S, Peroglio M, Menzel U, Benneker LM, Sakai D, Alini M, Grad S. 2018 Staphylococcus epidermidis infection progression and associated immune response in a murine fracture model: role of IL-17A.
2018 WIRM (poster)
Sabaté Brescó M, Berset C, Zeiter S, Richards RG, Moriarty F, O'Mahony L. 2018 Severe musculoskeletal polytrauma induces reduced anti-bacterial responses in neutrophils.
2018 WIRM (poster)Stanic B, Hofstee M, Stylianaki A, Morgenstern M, Richards RG, Moriarty TF, Thompson K. 2018 Identification and validation of immunogenic peptides of Staphylococcus epidermidis in the patients with bone infection.
2018 WIRM (poster)Stanic B, Morgenstern M, Thöny S, Konta M, Mercep M, Daiss JL, Schwarz EM, Richards RG, Moriarty TF. 2018 Mechanically induced chondrogenesis differentiation & biomarker discovery.
2018 ICRSStoddart M. 2018 Bioreactors & bioactive cartilage repair constructs.
2018 ICRSStoddart M. 2018 Effect of hyaluronan supplemented culture media on human mesenchymal stem cell chondrogenesis.
2018 ICRS (poster)Stoddart MJ, Monaco G, Alini M. 2018 Hyaluronic acid-based hydrogels promote mesenchymal stem cell ingrowth and cartilage production in vitro and in vivo.
2018 ICRS (poster)Vainieri ML, Sivasubramaniyan K, Lolli A, Eglin D, Yayon A, Wexselblatt E, Alini M, Grad S, van Osch G 2018 TGFß1 induces a contractile CD146+ phenotype of human annulus fibrosus cells showing affinity to a collagen gel.
2018 ISL&TLong R, Nakai T, Sakai D, Benneker LM, Iatridis JC, Alini M, Grad S, Li Z. 2018 Virtual modelling and planning workflows for CMF surgery.
2018 BG SOMSGueorguiev B, Noser H, Nilsson J, Voss J, Varjas V, Eglin D, Stoddart M, Kamer L. 2018 Non-Unions: Just a biomechanical problem?
2018 MOAGueorguiev B, Ernst M, Schwyn R, Richards RG, Windolf M. 2018 Why and how do locking plates fail?
2018 MOAGueorguiev B, Lenz M. 2018 Serum biomarkers for Modic changes among chronic low back pain patients.
2018 ISSLSKarppinen J, Koivisto K, Ketola J, Haapea M, Paananen M, Herzig K-H, Alini M, Lotz J, Dudli S, Samartzis D, Risteli J, Majuri M-L, Alenius H, Kyllönen E, Järvinen J, Niinimäki J, Grad S. 2018 Autologous nucleus pulposus cell-seeded hydrogel implantation to isolated human intervertebral discs promotes tissue repair during physiological culture.
2018 ISSLSRosenzweig D, Fairag R, Eglin D, Mathieu A, Weber M, Quellet J, Steffen T, Haglund L. 2018 Validation of anti-inflammatory and regenerative drug therapy in a bioreactor-guided intervertebral disc organ culture model.
2018 ISSLS (poster)Grad S, Li Z, Heizmann F, Liu Y, Geries J, Kubosch DC, Südkamp N, Alini M, Lang GM. 2018 Stimuli Responsive Hydrogels for Cellular Microenvironment Engineering.
2018 AFPMEglin D. 2018 Does RIA diameter influence femoral bone strength, fracture geometry and amount of harvested bone graft?
2018 EFORTSchmitz N, Gehweiler D, Wähnert D, Zderic I, Grünwald L, Richards RG, Raschke M, Gueorguiev B. 2018 Does bone cement augmentation increase the fixation strength and cut-out resistance of TFNA helical blades and screws?
2018 EFORTSermon A, Zderic I, Gehweiler D, Wahl D, Khatchadourian R, Scherrer S, Gueorguiev B. 2018 A new gliding screw concept for plating of proximal humerus fractures.
2018 EFORT (poster)Acklin Y, Zderic I, Inzana J, Grechenig S, Schwyn R, Windolf M, Richards RG, Gueorguiev B. 2018 Does supplemental dorsal plating increase stability of distal radius fractures after volar plating?
2018 EFORT (poster)Hadzhinikolova M, Zderic I, Ciric D, Enchev D, Baltov A, Rusimov L, Richards RG, Gueorguiev B, Rashkov M. 2018 Does supplemental intramedullary grafting increase stability of plated proximal humerus fractures?
2018 EFORT (poster)Rusimov L, Zderic I, Ciric D, Barcik J, Enchev D, Rashkov M, Hadzhinikolova M, Richards RG, Gueorguiev B, Baltov A. 2018 Guillaume O, Geven M, Schmid T, Grijpma D, Bos RRM, Richards RG, Alini M, Eglin D. 2018 Vainieri L, Sivasubramaniyan K, Lolli A, Eglin D, Yayon A, Wexselblatt E, Alini M, Grad S, Van Osch G. 2018 Fortunato G, De Maria C, Eglin D, Serra T, Vozzi G. 2018 Hatt P, Serra T, Eglin D. 2018 Petta D, Armiento A, Grijpma DW, Alini M, Eglin D, D’Este M. 2018 Biodegradable and bone targeting drug delivery system for antibiotics.
2018 SSB+RM (poster)Rotman SG, Grijpma DW, Richards RG, Moriarty TF, Eglin D, Guillaume O. 2018 Sprecher CM, Thurner M, Büchler P, Richards RG, Eglin D. 2018 Wahl P, Meier C, Dommann A, Neels A, Sprecher CM. 2018 Degradation of magnesium alloy and bone formation in vivo: micro-CT.
2018 SSB+RM (poster)Xu Y, Meng H, Eglin D, Peng J, Lu S. 2018 Staphylococcus epidermidis infection progression and associated immune response in a murine fracture model: role of biomechanical stability.
2018 asm microbe (poster)Sabaté Bresco M, Berset C, Zeiter S, Richards RG, O'Mahony L, Moriarty TF. 2018 Varga P, Windolf M. 2018 Helfen T, Siebenbürger G, Fleischhacker E, Biermann N, Sprecher C, Böcker W, Ockert B. 2018 Ma J, Stefanoska D, van Donkelaar CC, Grad S, Alini M, Peroglio M. 2018 Stoddart MJ. 2018 Behrendt P, Ladner Y, Stoddart MJ, Lippross S, Alini M, Eglin D, Armiento AR. 2018 Kovermann N, Basoli V, Della Bella E, Alini M, Lischer C, Schmal H, Stoddart MJ, Kubosch EJ. 2018 Lang G, Gehlen Y, Heizmann F, Kubosch D, Südkamp NP, Alini M, Grad S, Li Z. 2018 Monaco G, Alini M, Stoddart MJ. 2018 Vainieri ML, Wahl D, van Osch G, Alini M, Grad S. 2018 Wangler S, Peroglio M, Li Z, Menzel U, Benneker LM, Richards RG, Alini M, Grad S. 2018 Ziadlou R, Grad S, Stoddart MJ, Wang X, Qin L, Barbero A, Martin I, Alini M. 2018 Antunes BP, Vainieri ML, Monsonego-Ornan E, Alini M, Grad S, Yayon A. 2018 Frauchiger DA, May RD, Zhang X, Stoyanov J, Bertolo A, Benneker LM, Sakai D, Grad S, Tryfonidou MA, Gantenbein B. 2018 Korch V, Armiento A, Stoddart M, Schmal H, Südkamp NP, Kubosch EJ. 2018 Leite Pereira C, Cunha C, Teixeira GQ, D'Este M, Eglin D, Alini M, Grad S, Barbosa MA, Goncalves RM. 2018 Biphasic bioabsorbale osteochondral scaffold.
2018 eCM (poster)Meng X, Li L, Lai Y, Grad S, Alini M, Qin L, Wang X. 2018 Rosenzweig DH, Fairag R, Mathieu AP, Li L, Eglin D, D'Este M, Steffen T, Weber MH, Quellet JA, Haglund L. 2018 Weitkamp JT, Benz K, Lippross S, Eglin D, Armiento A, Seekamp A, Kurz B, Behrendt P. 2018 Acklin Y, Zderic I, Inzana J, Grechenig S, Schwyn R, Windolf M, Richards RG, Gueorguiev B. 2018 Hadzhinikolova M, Zderic I, Ciric D, Enchev D, Baltov A, Rusimov L, Richards RG, Gueorguiev B, Rashkov M. 2018 Schmitz N, Gehweiler D, Wähnert D, Zderic I, Grünwald L, Richards RG, Raschke M, Gueorguiev B.