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Fax:    +41 44 200 24 60

AOCID Resources

Useful resources to help you conduct clinical research.

Classification Tool

The AOCOIAC (Comprehensive Injury Automatic Classifier) is a PC-based software developed at AO Clinical Investigation and Documentation for AOTrauma and AOCMF in the context of the activities of the AO Classification Advisory Group. AO COIAC helps surgeons learn and use AO classification systems for clinical diagnosis and simple local case documentation. The current version includes the Müller AO Classification of Fractures – Long Bones for adults, the AO pediatric long bone classification system, as well as a newly developed AO craniomaxillofacial system for injury location. More than 5,000 downloads demonstrate the worldwide interest in the AO COIAC as a software solution. More...


This FREE pocket reference for Good Clinical Practice guidelines is a helpful tool to make your job easier, courtesy of ACRP.

Android and iPhone versions are available. For more information please click here.

Webinars and Videos


Spanish language webinar
Paula Sotelo de Chile y el Dr. Shandher Tovar de Perú revisaron los aspectos fundamentales a tener en cuenta para la realización de una investigación clínica.
Running time 60 minutes.


How to write a good clinical study grant application.
Presented by Beate Hanson, AOCID Director, and Dr Stephen Kates. Running time 60 minutes.


The Clinical Research Casino – Statistical concepts found in gambling and clinical studies.
Presented by Beate Hanson, AOCID Director. Running time 62 minutes.


Evidence-based practice in the operating room.
Lecture to ORP by Beate Hanson, AOCID Director. Running time 23 minutes.


AOCID's Services

Müller AO Classification of Fractures – Long Bones

AO Pediatric Comprehensive Classification of Long-Bone Fractures


The TEFTOM (Trauma Expectation Factor / Trauma Outcome Measure) tools will assist you in identifying patient expectations prior to surgery, and measuring how successful you were in fulfilling them post-surgery.

TEF Questionnaire

TOM Questionnaire


Site feasibility checklist

Are you interested in seeing what the requirements are for a clinic to take part on an AOCID study? For information purposes only, please see the site feasibility checklist developed for a clinical investigation.


TMT Fusion RCT feasibility questionnaire for sites_v1.0.pdfTMT Fusion RCT feasibility questionnaire



Ethical Principles for Medical Research Involving Human Subjects
WMA Declaration of Helsinki

WHO – Research ethics

Clinical Research

Oxford Centre for Evidence-Based Medicine. Great resources like critical appraisal checklists.

Presentation on the history of clinical research.

Free to download books

A practical guide for health researchers by Mahmoud F. Fathalla and Mohamed M.F. Fathalla.
p. (WHO Regional Publications, Eastern Mediterranean Series; 30).

Freely downloadable texts of the 2006 and 2011 editions of the book Testing Treatments, together with reviews and translations of the first edition, are available at

This handbook from Quintiles is a collaborative effort between academia and industry and serves as an introductory guide to Investigator Initiated Trials (IIT). It provides theoretical and practical foundation for researchers who wish to conduct their own clinical trials. To download, please click here.

Freely downloadable text of both volumes of the book Registries for Evaluating Patient Outcomes: A User's Guide: 3rd Edition is available from the Agency for Healthcare Research and Quality (AHRQ).


International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use

U.S. Food and Drug Administration – Medical Devices

European Parliament and Council Directive on medical devices
European Parliament and Council DIRECTIVE 2007/47/EC

Implementation of good clinical practice in the conduct of clinical trials on medicinal products for human use
European Parliament and Council DIRECTIVE 2001/20/EC


Uniform Requirements for Manuscripts Submitted to Biomedical Journals
International Committee of Medical Journal Editors

Citations for biomedical literature from MEDLINE, life science journals, and online books.

The Cochrane Library
Independent high-quality evidence for health care decision making


Handbook – Statistics and Data Management
A Practical Guide for Orthopedic Surgeons. Sample chapter: How to analyze your data

Basics of Medical Statistics
A web-based course in medical statistics designed for students of medicine and those working in the medical professions. In English, French and German. Free registration.

Stata – Data Analysis and Statistical Software
Convenient web-based courses for learning Stata.

Free online sample size calculators

Electronic Data Capture

REDCap – Research Electronic Data Capture
A secure web application which supports electronic data capture for research studies.​